1 results match your criteria: "Clinical Pharmaceutical Research Institute of Second Xiangya Hospital of Central South University[Affiliation]"
Simultaneous determination of clozapine, olanzapine, risperidone and quetiapine in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
April 2004
Clinical Pharmaceutical Research Institute of Second Xiangya Hospital of Central South University, Changsha 410011, PR China.
Unlabelled: Clozapine (CLZ), olanzapine (OLZ), risperidone (RIP) and quetiapine (QTP) have been widely used in the treatment of schizophrenia. However, no study (or little study) has been conducted to determine the four drugs simultaneously by the use of high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-MS/ESI).
Objective: To develop a sensitive method for simultaneous determination of CLZ, OLZ, RIP and QTP in human plasma by HPLC-MS/ESI.