22 results match your criteria: "Clinical Orthopaedic Research Hvidovre (CORH)[Affiliation]"

Article Synopsis
  • This study analyzed the effects of age on outcomes for patients undergoing medial unicompartmental knee arthroplasty (mUKA), revealing that contemporary practices no longer limit eligibility based on age.
  • A total of 782 patients were evaluated, showing significant improvements in knee function across all age groups after surgery, with no notable differences in the overall outcomes based on age.
  • However, patients aged 55 to < 65 years experienced less improvement in specific measures of joint awareness and participation, but overall satisfaction was high across all age categories, supporting the current approach of not using age as a restriction for mUKA.
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Article Synopsis
  • The study aimed to understand how the distribution of knee arthroplasties performed by orthopaedic surgeons affects patient outcomes, specifically focusing on patient-reported outcome measures (PROMs) after surgery.
  • A total of 2,256 knee arthroplasties were analyzed, with PROMs assessed at various time points to compare outcomes based on surgical groups defined by their proportion of medial unicompartmental knee arthroplasties (UKAs).
  • Results showed that the group of surgeons performing at least 20% medial UKA had significantly better PROM improvements at 3 and 12 months post-surgery, suggesting that a higher proportion of this type of procedure is beneficial for patient outcomes.
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Genetics may affect the risk of undergoing surgery for rhizarthrosis.

J Orthop Res

May 2024

Clinical Orthopaedic Research Hvidovre (CORH), Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Article Synopsis
  • * A study involving 208,342 individuals explored how genetic variations affect the need for surgical versus nonsurgical treatment in patients with trapeziometacarpal osteoarthritis (rhizarthrosis), identifying 10 significant genetic variants related to treatment differences.
  • * The findings indicate that genetic associations in rhizarthrosis can differ based on treatment status, which could help in understanding the biology behind the disease and guiding future clinical decisions.
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Article Synopsis
  • - The study aimed to analyze the reasons for revision surgeries in unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) over the past 20 years and examine how surgical practices have evolved during this time.
  • - After reviewing data from knee surgeries in Denmark between 1997 and 2017, the researchers found that aseptic loosening was the top reason for revisions in both types of surgeries, while pain and disease progression were significant considerations for UKA revisions.
  • - The findings indicated a notable decrease in revisions due to pain and loosening in recent years, suggesting that changes in surgical techniques and practices led to better outcomes for UKA patients compared to previous trends.
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Objective: To describe 1) the proportion of patients with knee osteoarthritis (OA) undergoing guideline-adherent core treatments until six months after primary referral to an orthopaedic surgeon, 2) which specific treatment pathways these patients undertake and 3) the characteristics of patients choosing different treatment pathways.

Design: This prospective cohort study consecutively invited patients referred to an orthopaedic surgeon due to knee OA at two Danish hospitals from October 2018 to December 2020. Before and six months after consulting the surgeon, patients answered a questionnaire reporting which treatments they had received for knee OA.

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Use of a tourniquet is not associated with increased risk of venous thromboembolism after fast-track total knee arthroplasty: a prospective multicenter cohort study of 16,250 procedures.

Acta Orthop

July 2023

Lundbeck Foundation Centre for Fast-track Hip and Knee Arthroplasty, Rigshospitalet, Copenhagen; Department of Orthopaedic Surgery, Clinical Orthopaedic Research Hvidovre (CORH), Copenhagen University Hospital Hvidovre, Hvidovre.

Background And Purpose: Venous thromboembolism (VTE) is a serious postoperative complication after total knee arthroplasty (TKA). Use of a tourniquet has shown conflicting results for risk of VTE after TKA. We aimed to investigate the associated risk of VTE after TKA using tourniquet in a fast-track set-up as no previous data exists.

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Background And Purpose: In existing studies on fasttrack unicompartmental knee arthroplasty (UKA), the majority of surgeries are medial. There are substantial differences between lateral and medial UKA, which is why outcomes cannot automatically be compared. To gain information on the feasibility and safety of fast-track protocols in lateral UKAs, we investigated length of stay (LOS) and early complications after lateral UKA, performed using a fast-track protocol in well-established fast-track centers.

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Article Synopsis
  • Osteoarthritis is a common disease influenced by genetics, but its impact on disease progression and the need for joint replacement is not well understood.
  • * This study analyzed over 700,000 individuals, comparing genetic variants in patients with and without joint replacements for knee and hip osteoarthritis.
  • * Findings revealed 52 genetic variants linked to osteoarthritis, with variations in associations based on whether patients had surgery, suggesting distinct genetic influences on disease outcomes.*
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Background: In this study, we examined the association between obesity and patient-reported outcome measures after medial unicompartmental knee arthroplasty (MUKA), assessed through score changes, Patient Acceptable Symptom State (PASS), and minimal important change (MIC). Second, the association between obesity and early readmissions was examined.

Methods: A total of 450 MUKAs (mean body mass index [BMI] 30.

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Background And Purpose: Unicompartmental knee arthroplasty (UKA) has increased in use. We investigated changes to UKA revision risk over the last 20 years compared with total knee arthroplasty (TKA), examined external and patient factors for correlation to UKA revision risk, and described the survival probability for current UKA and TKA practice.

Patients And Methods: All knee arthroplasties reported to the Danish Knee Arthroplasty Register from 1997 to 2017 were linked to the National Patient Register and the Civil Registration System for comorbidity, emigration, and mortality information.

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Interpretation of the Achilles tendon Total Rupture Score (ATRS) is challenging because limited knowledge exists about at which score the patients consider the outcome of treatment as satisfactory. The aims of the study were (1) to describe the proportion of patients who find their symptom levels to be satisfactory, to reflect treatment failure or neither after acute Achilles tendon rupture (ATR), and (2) to estimate the Patient Acceptable Symptom State (PASS) and the Treatment Failure (TF) threshold values for the ATRS at 6 months, 1 year, and 2 years after ATR. The study was based on data extracted from the nationwide Danish Achilles tendon Database which includes patients treated operatively or nonoperatively after ATR.

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Introduction: Knee osteoarthritis (OA) is associated with chronic knee pain and functional disability that negatively affect the ability to carry out normal daily activities. Patients are offered a large variety of non-surgical treatments, often not in accordance with clinical guidelines. This observational study will provide a comprehensive overview of treatment pathways for knee OA during the first 2 years after consulting an orthopaedic surgeon, including timing and order of treatment modalities, predictors of treatment outcomes, cost-effectiveness of treatment pathways and patients' views on different treatment pathways.

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Background: Whether to use unicompartmental knee arthroplasty (UKA) or total knee arthroplasty (TKA) for appropriate osteoarthritis cases is a subject of debate. UKA potentially offers faster recovery and fewer short-term complications. However, reported differences in preoperative comorbidity between TKA and UKA-treated patients could affect outcomes.

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Objectives: The objective of the study was to create an interpretive categorical classification for the transition in the Oxford Knee Score (OKS) change score (ΔOKS) using the anchor-based method.

Study Design And Setting: Registry data from 46,094 total knee replacements from the year 2014/15, were accessed via the Health and Social Care Information Center official website. Data included preoperative and 6-month follow-up OKS and response to the transition anchor question.

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Background and purpose - Enhanced recovery programs have reduced length of stay (LOS) after hip and knee arthroplasty (THA/TKA). Although risk factors disposing to prolonged LOS are well documented, there is limited information on the role of weekday of surgery. This study analyzed the role of weekday of surgery and other potential risk factors for LOS > 2 days.

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Aims: The aim of this prospective multicentre study was to describe trends in length of stay and early complications and readmissions following unicompartmental knee arthroplasty (UKA) performed at eight different centres in Denmark using a fast-track protocol and to compare the length of stay between centres with high and low utilization of UKA.

Methods: We included data from eight dedicated fast-track centres, all reporting UKAs to the same database, between 2010 and 2018. Complete ( > 99%) data on length of stay, 90-day readmission, and mortality were obtained during the study period.

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Introduction: Unicompartmental knee arthroplasty (UKA) has increased due to potential favourable complication rates when compared to total knee arthroplasty (TKA). Although venous thromboembolism (VTE) is a well-documented complication after TKA limited data is available after UKA and mostly presented as secondary findings in observational comparisons to TKA. There is a lack of fast-track UKA VTE studies and no guidelines on thromboprophylaxis.

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Background and purpose - Using contemporary indications, up to 50% of patients undergoing knee arthroplasty are eligible for unicompartmental knee arthroplasty (UKA), and lower UKA use likely reflects a restrictive approach to patient selection. Since broader indications have been successfully introduced, and low surgical volume and UKA percentage (usage) are associated with higher revision rates, it is of interest whether the actual use of UKA has changed accordingly. We explored this by assessing time trends in patient demographics and whether these are associated with center UKA volume and usage.

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Background and purpose - Obesity is a rising issue worldwide and growing evidence supports poor outcome amongst obese patients following total knee arthroplasty (TKA). Using nationwide registries we investigated the association between bodyweight and risk of revision of primary TKA. Patients and methods - All primary TKA performed during 1997-2015, weight at time of primary TKA and subsequent TKA revisions were identified in the Danish Knee Arthroplasty Register (DKR).

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Background: Reduced lower extremity muscle strength as well as reduced lower extremity muscle pre-activity (defined as muscular activity just prior to initial ground contact) during high-risk movements are factors related to increased risk of non-contact ACL injury in adolescent female athletes. A strong relationship exists between muscle strength and muscle activity obtained during an isometric contraction, however, whether these two measures are related when muscle activity is obtained during a movement associated with a high risk of non-contact ACL injury is not known. Absence or presence of such a relationship may have implications for which training modalities to choose in the prevention of ACL injuries.

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