A New Design of a Lead-Acrylic Shield for Staff Dose Reduction in Radial and Femoral Access Coronary Catheterization.

Purpose: Today's standard radiation protection during coronary angiography and percutaneous coronary interventions is the combined use of lead acrylic shields and table-mounted lower body protection. Ambient dose measurements, however, have shown that these protection devices need improvement.

Materials And Methods: Using an anthropomorphic physical phantom, various scenarios were investigated with respect to personnel exposure: a) enlarging the shield b) adding a flexible protective curtain to the bottom side of the shield, and c) application of radioprotective patient drapes.

Effect of glucagon-like peptide-1 receptor antagonism on appetite and food intake in healthy men.

Background: Exogenous glucagon-like peptide-1 (GLP-1) inhibits eating in healthy, overweight, and diabetic subjects.

Objective: The GLP-1 receptor antagonist exendin(9-39)NH2 (ex9-39) was used to further explore the role of GLP-1 as an endogenous satiation signal.

Design: Two double-blind, 4-way crossover studies were performed, each of which included 10 healthy men.

Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade.

Understanding the incretin pathway has led to significant advancements in the treatment of type 2 diabetes (T2D). Still, the exact mechanisms are not fully understood. In a randomized, placebo-controlled, four-period, crossover study in 24 patients with T2D, dipeptidyl peptidase-4 (DPP-4) inhibition and its glucose-lowering actions were tested after an oral glucose tolerance test (OGTT).

The role of endogenous incretin secretion as amplifier of glucose-stimulated insulin secretion in healthy subjects and patients with type 2 diabetes.

In order to quantify the role of incretins in first- and second-phase insulin secretion (ISR) in type 2 diabetes mellitus (T2DM), a double-blind, randomized study with 12 T2DM subjects and 12 healthy subjects (HS) was conducted using the hyperglycemic clamp technique together with duodenal nutrition perfusion and intravenous infusion of the glucagon-like peptide 1 (GLP-1) receptor antagonist exendin(9-39). Intravenous glucose alone resulted in a significantly greater first- and second-phase ISR in HS compared with T2DM subjects. Duodenal nutrition perfusion augmented both first- and second-phase ISR but first-phase ISR more in T2DM subjects (approximately eight- vs.

Successful antibiotic treatment of severe staphylococcal infection of a long stent graft in the superficial femoral artery with graft preservation in the long term.

Introduction: Bacterial infection of endovascular stent grafts is a serious condition, regularly leading to graft replacement by open bypass surgery.

Case Report: We describe the case of a staphylococcal infection of a 150-mm covered stent graft (Gore Viabahn), placed in the superficial femoral artery. Stent graft infection was successfully treated by oral administration of penicillinase-resistant flucloxacillin and the lipopeptide daptomycin with complete graft preservation, not requiring surgical treatment.

Rotational thrombectomy of acute peripheral vascular occlusions using the ThromCat XT device: techniques, indications and initial results.

Purpose: To gather initial procedural experiences with the ThromCat XT, a new rotational thrombectomy catheter primarily developed for coronary interventions.

Materials And Methods: The ThromCat XT is a 150-cm rapid exchange thrombectomy device consisting of an atraumatic tip and a steel helix with a kink-resistant covering. It was employed in native arteries, veins, grafts and stents in ten patients presenting with acute and subacute thrombembolic occlusions.

Assessment of renal vasoconstriction in vivo after intra-arterial administration of the isosmotic contrast medium iodixanol compared to the low-osmotic contrast medium iopamidol.

Background: Low-osmotic contrast media (LOCM) such as iopamidol are known to increase the renal resistance index (RRI). The aim of our study was to evaluate in vivo the different effects of intra-arterial administration of LOCM in comparison to isosmotic contrast medium (IOCM) such as iodixanol on the human RRI.

Methods: Twenty patients (16 males, 4 females; 66 years on average) with normal renal function (mean creatinine 1.

Assessment of the vessel lumen diameter and degree of stenosis in the superficial femoral artery before intervention: comparison of different algorithms.

Purpose: To determine which angiography-based algorithm delivers the most precise results in comparison with direct measurements at intravascular ultrasonography (US) and evaluate their influence on the resulting balloon size for treatment.

Materials And Methods: Thirty patients with untreated superficial femoral artery stenosis underwent digital subtraction angiography (DSA) and intravascular US before intervention. Two experienced radiologists measured twice the native vessel lumen diameter and the degree of stenosis with all algorithms and modalities in a predefined vessel segment that was perceived to be unaffected.

IT services in a completely digitized radiological department: value and benefit of an in-house departmental IT group.

To analyze the benefit of a departmental IT group in comparison to support by hospital IT groups or system manufacturers in a completely digitized radiological department. The departmental IT group comprises a fulltime IT specialist, two student assistants and four clinical employees participating 1 day/week. For 18 months IT problems were quantified and specified according to urgency, responsibility and affected system by use of an intranet-based reporting system.