121 results match your criteria: "Clinic of Diagnostic and Interventional Radiology[Affiliation]"

The aim of this study was to evaluate patients with hereditary hemorrhagic telangiectasia (HHT) for the potential reperfusion of pulmonary arteriovenous malformations (PAVM) treated by catheter embolization using coils or embolization plugs and to analyze causes of possible reperfusion in order to further improve treatment. This retrospective study analyzed the data of 345 patients who underwent screening for pulmonary arteriovenous malformations in cases of suspected or confirmed HHT (Osler's disease). Of these, 118 patients with PAVM that underwent catheter embolization and had at least one follow-up study were included in our study and evaluated for potential reperfusion.

View Article and Find Full Text PDF

Interventional oncology (IO) employs various techniques to enable minimally invasive, image-guided treatment of tumor diseases with both curative and palliative goals. Additionally, it significantly contributes to managing tumor-related and perioperative complications, offering diverse supportive procedures for patients at all stages of their diseases. The execution of IO procedures places unique demands on the equipment, personnel, and structural organization of radiological clinics, necessitating specific expertise from interventional radiologists.

View Article and Find Full Text PDF

The influence of contrast media on calcium-based imaging of the spine in dual-layer CT.

Sci Rep

August 2024

Clinic of Diagnostic and Interventional Radiology (DIR), Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.

This study aimed to evaluate the impact of contrast media application on CT attenuation of the bone using a novel calcium-only imaging technique (VCa) from dual-layer spectral detector CT (DLCT), which enables CT-based bone mineral density measurement unimpeded by soft tissue components. For this, true non-contrast (TNC) and venous phase images (VP) of n = 97 patients were acquired. CT attenuation of the first lumbar vertebra (L1) was measured in TNC-VCa, VP-VCa, and in virtual non-contrast images (VNC).

View Article and Find Full Text PDF

Purpose: To evaluate the prediction of vertebral fractures in plasma cell dyscrasias using dual-layer CT (DLCT) with quantitative assessment of conventional CT image data (CI), calcium suppressed image data (CaSupp), and calculation of virtual calcium-only (VCa) image data.

Material And Methods: Patients ( = 81) with the diagnosis of a plasma cell dyscrasia and whole-body DLCT at the time of diagnosis and follow-up were retrospectively enrolled. CI, CaSupp25, and CaSupp100 were quantitatively analyzed using regions of interest in the lumbar vertebral bodies and fractured vertebral bodies on baseline or follow-up imaging.

View Article and Find Full Text PDF

Reduced iodine loads for computed tomography (CT)-based vascular assessment prior to transcatheter aortic valve implantation (TAVI) may be feasible in conjunction with a spectral detector CT scanner. This prospective single-center study considered 100 consecutive patients clinically referred for pre-TAVI CT. They were examined on a dual-layer detector CT scanner to obtain an ECG-gated cardiac scan and a non-ECG-gated aortoiliofemoral scan.

View Article and Find Full Text PDF

The rapid evolution of artificial intelligence (AI), particularly in deep learning, has significantly impacted radiology, introducing an array of AI solutions for interpretative tasks. This paper provides radiology departments with a practical guide for selecting and integrating AI solutions, focusing on interpretative tasks that require the active involvement of radiologists. Our approach is not to list available applications or review scientific evidence, as this information is readily available in previous studies; instead, we concentrate on the essential factors radiology departments must consider when choosing AI solutions.

View Article and Find Full Text PDF
Article Synopsis
  • Congenital mesoblastic nephroma is the most common solid kidney tumor in newborns, and MRI is the preferred method for diagnosis, especially in differentiating it from Wilms tumor.
  • This study involved a review of MRI scans from 52 confirmed cases of congenital mesoblastic nephroma, categorizing them into classic, cellular, and mixed types, with a focus on their distinct MRI characteristics.
  • Key findings revealed that the classic type was more homogeneous and smaller, while cellular and mixed types were larger and more heterogeneous, with specific MRI signaling patterns noted across all cases.
View Article and Find Full Text PDF

Purpose: Several studies report occupational orthopedic problems among interventional cardiologists. These health problems are usually multifactorial. However, the personal protective equipment used should play a major role.

View Article and Find Full Text PDF

The management of fractured bones is a key domain within orthopedic trauma surgery, with the prevention of delayed healing and non-unions forming a core challenge. This study evaluates the efficacy of the AO Fracture Monitor in conjunction with biomechanical simulations to better understand the local mechanics of fracture gaps, which is crucial for comprehending mechanotransduction, a key factor in bone healing. Through a series of experiments and corresponding simulations, the study tests four hypotheses to determine the relationship between physical measurements and the predictive power of biomechanical models.

View Article and Find Full Text PDF

Purpose: Recent advancements in medical imaging have transformed diagnostic assessments, offering exciting possibilities for extracting biomarker-based information. This study aims to investigate the capabilities of a machine learning classifier that incorporates dual-energy computed tomography (DECT) radiomics. The primary focus is on discerning and predicting outcomes related to pulmonary embolism (PE).

View Article and Find Full Text PDF

Metabolic dysfunction-associated steatotic liver disease is a growing global public health concern. Quantitative ultrasound measurements, such as ultrasound-derived fat fraction (UDFF), could provide noninvasive, cost-effective, and portable steatosis evaluation. The purpose of this article was to evaluate utility of UDFF for steatosis assessment using proton density fat fraction (PDFF) as reference in patients undergoing liver MRI for heterogeneous indications and to assess UDFF variability.

View Article and Find Full Text PDF

Indicators for Hospitalization in Acute Pulmonary Embolism: Uncover the Association Between D-dimer Levels, Thrombus Volume and Radiomics.

Acad Radiol

June 2024

Goethe University Hospital Frankfurt, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany (J.G., L.D.G., T.G., K.E., S.S.M., S.M., C.B., T.B., P.R., J.J., T.J.V., V.K.).

Background: The advent of advanced computed tomography (CT) technology and the field of radiomics has opened up new avenues in diagnostic assessments. Increasingly, there is substantial evidence advocating for the incorporation of quantitative imaging biomarkers in the clinical decision-making process. This study aimed to examine the correlation between D-dimer levels and thrombus size in acute pulmonary embolism (PE) combining dual-energy CT (DECT) and radiomics and to investigate the diagnostic utility of a machine learning classifier based on dual-energy computed tomography (DECT) radiomics for identifying patients with a complicated course, defined as at least hospitalization at IMC.

View Article and Find Full Text PDF

A New Iterative Metal Artifact Reduction Algorithm for Both Energy-Integrating and Photon-Counting CT Systems.

Invest Radiol

July 2024

From the Siemens Healthineers, CT Physics, Forchheim, Germany (J.A.A., M.H., C.H.); Clinic of Diagnostic and Interventional Radiology, Philipps-University Marburg, Marburg, Germany (J.A.A., A.H.M.); and Infoteam Software AG, Bubenreuth, Germany (P.K.).

Article Synopsis
  • The study introduces a new metal artifact reduction framework called iMARv2, designed to improve image quality by addressing the limitations of the current iMAR method.
  • iMARv2 combines existing techniques with modular components for better artifact removal and allows users to adjust image strength settings for preferred quality.
  • Results showed that iMARv2 significantly increased diagnostic confidence, especially in cases with dental fillings, while only minor improvements were noted for spine cases, highlighting its potential for routine clinical use.
View Article and Find Full Text PDF

Incident fractures of the distal radius: Dual-energy CT-derived metrics for opportunistic risk stratification.

Eur J Radiol

February 2024

Goethe University Frankfurt, University Hospital, Department of Diagnostic and Interventional Radiology, Frankfurt am Main, Germany.

Background: Dual-energy CT (DECT)-derived bone mineral density (BMD) of the distal radius and other CT-derived metrics related to bone health have been suggested for opportunistic osteoporosis screening and risk evaluation for sustaining distal radius fractures (DRFs).

Methods: The distal radius of patients who underwent DECT between 01/2016 and 08/2021 was retrospectively analyzed. Cortical Hounsfield Unit (HU), trabecular HU, cortical thickness, and DECT-based BMD were acquired from a non-fractured, metaphyseal area in all examinations.

View Article and Find Full Text PDF

Background: This study aimed to evaluate the clinical utility of modern single and dual-energy computed tomography (CT) for assessing the integrity of the cruciate ligaments in patients that sustained acute trauma.

Methods: Patients who underwent single- or dual-energy CT followed by 3 Tesla magnetic resonance imaging (MRI) or knee joint arthroscopy between 01/2016 and 12/2022 were included in this retrospective, monocentric study. Three radiologists specialized in musculoskeletal imaging independently evaluated all CT images for the presence of injury to the cruciate ligaments.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate bone health index (BHI) changes in short-statured children receiving growth hormone (GH) treatment over a long period.
  • A total of 256 children with various conditions related to short stature were assessed using radiographs to track their bone health before and after starting GH therapy from 2010 to 2018.
  • The results showed that while BHI was initially low in these children, it improved significantly after one year of GH treatment and continued to show sustained improvement over time, indicating better bone health.
View Article and Find Full Text PDF
Article Synopsis
  • Cancer patients are at a higher risk for venous thromboembolism (VTE), but traditional D-dimer testing combined with clinical assessment may not be as effective in this group.
  • D-dimer levels can help rule out VTE, and if elevated beyond ten times the normal limit, may indicate a high probability of VTE with over 80% positive predictive value, while also providing prognostic information about cancer severity and potential outcomes.
  • There is a need for standardizing D-dimer testing protocols and creating tailored models for assessing cancer patients to improve diagnostic accuracy for VTE.
View Article and Find Full Text PDF

Feasibility and safety of ADAPT in acute distal posterior cerebral artery occlusions.

Eur J Radiol

August 2023

Department of Radiology and Neuroradiology, Sana Kliniken Duisburg, Duisburg, Germany.

Purpose: The direct aspiration first pass technique (ADAPT) is an effective and safe endovascular treatment for distal medium vessel occlusions (DMVO) of the anterior circulation. Clinical experience with ADAPT in the distal posterior circulation, however, is still limited and published data is scarce. In this original work, feasibility, safety and efficacy of ADAPT with distal access catheters (DAC) for treatment of acute distal posterior cerebral artery occlusions (DPCAOs) is evaluated.

View Article and Find Full Text PDF
Article Synopsis
  • Nonspecific chest pain in patients with heart devices, like pacemakers, should make doctors think about possible issues with the device, even if tests look normal.
  • A 77-year-old woman had chest pain a year after getting her pacemaker, which turned out to be due to a serious problem with the device's lead.
  • It's important for doctors and patients to be aware that problems with heart devices can happen long after they are put in, so any unusual pain should be checked out carefully.
View Article and Find Full Text PDF

Objective: The objective of this study is to examine the performance of new generation protection aprons as alternative to conventional lead aprons regarding their radiation protection effectiveness.

Method And Materials: Radiation protection aprons made of lead-containing and lead-free materials from a total of seven companies were compared. Furthermore, different lead equivalent values of 0.

View Article and Find Full Text PDF

Associations of SLC6A4 methylation with salivary cortisol, salivary alpha-amylase, and subjective stress in everyday life.

Psychoneuroendocrinology

July 2023

Institute of Medical Psychology, Center for Psychosocial Medicine, Heidelberg University Hospital, Ruprecht-Karls University Heidelberg, Bergheimer Straße 20, 69115 Heidelberg, Germany. Electronic address:

Dysregulations of the hypothalamic-pituitary-adrenal (HPA) and sympatho-adrenal medullary (SAM) axis are associated with mental and somatic illness. However, there is lack of knowledge regarding the molecular mechanisms underlying these effects. Epigenetic states in the serotonin transporter gene (SLC6A4) were shown to be associated with stress in various forms.

View Article and Find Full Text PDF

Background: The advent of next-generation computed tomography (CT)- and magnetic resonance imaging (MRI) opened many new perspectives in the evaluation of tumor characteristics. An increasing body of evidence suggests the incorporation of quantitative imaging biomarkers into clinical decision-making to provide mineable tissue information. The present study sought to evaluate the diagnostic and predictive value of a multiparametric approach involving radiomics texture analysis, dual-energy CT-derived iodine concentration (DECT-IC), and diffusion-weighted MRI (DWI) in participants with histologically proven pancreatic cancer.

View Article and Find Full Text PDF

Purpose: To present a preclinical in vivo approach for standardization and training of lymphangiography and lymphatic interventions using a pictorial review.

Materials And Methods: Different lipiodol- and gadolinium-based lymphangiography and lymphatic interventions were performed in twelve (12) landrace pigs with a mean bodyweight of 34 ± 2 kg using various imaging and guiding modalities, similar to the procedures used in humans. The techniques used were explicitly introduced and illustrated.

View Article and Find Full Text PDF

Purpose: Re-entry devices contribute to the high success rate of subintimal recanalization of chronic total occlusions (CTO). However, to date, there are no studies comparing the available conventional re-entry devices concerning the impact of their technical success on economic aspects, as these devices differ greatly in their acquisition costs. This prospective observational study intends to contribute to this question.

View Article and Find Full Text PDF

Purpose: To investigate the effect of the ongoing COVID-19 pandemic on interventional radiology (IR) in Germany in 2020 and 2021.

Materials Und Methods: This retrospective study is based on the nationwide interventional radiology procedures documented in the quality register of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR-QS-Register). The nationwide volume of interventions in the pandemic years 2020 and 2021 was compared with the pre-pandemic period (Poisson-test, Mann-Whitney test).

View Article and Find Full Text PDF