39 results match your criteria: "Clinic of Biochemistry[Affiliation]"
J Turk Ger Gynecol Assoc
December 2024
Clinic of Obstetrics and Gynecology, University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.
Objective: The question of whether severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection influences ovarian function and oocyte quality has arisen as angiotensin converting enzyme-2 receptors, which facilitates viral infection, are found on reproductive system tissues, including the vagina, placenta, uterus, and ovaries. The primary objective of this prospective study was to evaluate the impact of SARS-CoV-2, on ovarian function, with a focus on anti-Mullerian hormone (AMH) and acute phase reactant levels in patients well after recovery from coronavirus disease-2019 (COVID-19).
Material And Methods: This prospective cohort study was conducted in the department of obstetrics and gynecology at a single center between October 2020 and June 2021.
J Turk Ger Gynecol Assoc
December 2024
Department of Obstetrics and Gynecology, Mediliv Medical Center, Samsun, Turkey
Objective: The aim of this study was to investigate the developmental potential of immature oocytes and evaluate whether unstimulated in vitro maturation (IVM) could serve as a treatment option for women with oocyte maturation abnormalities (OMAs).
Material And Methods: This cohort study was conducted between September 2019 and December 2022, and included women who underwent unstimulated, non-human chorionic gonadotropin (hCG) priming IVM. Oocytes were incubated with IVM medium for 26-48 hours and evaluated to compare their maturation profiles with the immature oocytes retrieved from the same patients in their previous in vitro fertilization cycles.
J Clin Res Pediatr Endocrinol
May 2024
Govind Ballabh Pant Institute of Post-graduate Medical Training and Research, Clinic of Cardiology, New Delhi, India
Objective: To estimate the proportion and risk factors of non-thyroidal illness (NTI) in children with congenital heart disease (CHD) with congestive heart failure (CHF).
Methods: This study enrolled children (6 weeks to 60 months age) with CHD and CHF. The clinical profile and disease severity, derived from the Pediatric Early Warning Score (PEWS) was recorded.
J Clin Res Pediatr Endocrinol
May 2024
University of Health Sciences Turkey, Antalya Training and Research Hospital, Clinic of Biochemistry, Antalya, Turkey
Objective: Prader-Willi syndrome (PWS) and Bardet-Biedl syndrome (BBS) are causes of pediatric syndromic obesity. We aimed to investigate a possible role for ghrelin and glucagon-like peptide-1 (GLP-1) in the pathophysiology of PWS and BBS.
Methods: The study included 12 children with PWS, 12 children with BBS, 13 pediatric obese controls (OC) and 12 pediatric lean controls (LC).
J Infect Dev Ctries
October 2023
Department of Internal Medicine, Intensive Care Unit, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey.
Int J Clin Pract
March 2023
Department of Critical Care, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey.
/. Coronavirus disease 2019 (COVID-19) is a life-threatening disease characterized by a prothrombotic state. Because homocysteine (Hcy) is a potential biomarker in thrombotic disease, this article aims to highlight the role of Hcy in the prognosis of COVID-19 pneumonia.
View Article and Find Full Text PDFTuberk Toraks
December 2022
Clinic of Biochemistry, Health Sciences University Tepecik Research and Training Hospital, İzmir, Türkiye.
Introduction: Respiratory abnormalities in obstructive sleep apnea syndrome (OSAS) are corrected with positive pressure ventilation treatments. We investigated the effect of positive airway pressure (PAP) treatment on the serum level of ischemia-modified albumin (IMA), an oxidative stress product, in OSAS patients with higher body mass index (BMI) and indication for PAP treatment.
Materials And Methods: Seven consecutive female and 23 male patients with a BMI of ≥30 kg/m2 who were diagnosed as having OSAS according to ICSD3 criteria and were planned for PAP, were included.
Medeni Med J
September 2022
Recep Tayyip Erdogan University Faculty of Medicine, Department of Pathology, Rize, Turkey.
Objective: Endometrioid endometrial carcinomas (EEC) are the most commonly diagnosed malignancies of the female genital tract. Myometrial invasion depth is one of the most significant pathological prognostic parameters. Different morphological invasion patterns have been characterized.
View Article and Find Full Text PDFJ Obstet Gynaecol
August 2022
Clinic of Obstetrics and Gynecology, University of Health Sciences, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
This study was conducted to examine the levels of vitamin D in postterm pregnancy. The study consisted of two groups: Group 1: women with postterm pregnancy in whom labour has not started ( = 40). Group 2: pregnant women with spontaneous labour between 37 and 41 weeks of gestation ( = 40).
View Article and Find Full Text PDFTurk J Obstet Gynecol
September 2021
University of Health Sciences Turkey, Konya City Hospital, Clinic of Obstetrics and Gynecology, Konya, Turkey
Objective: We aim to study the relationship between atherosclerosis and serum sclerostin levels in different phenotypes of polycystic ovary syndrome (PCOS).
Materials And Methods: A total of 134 women with PCOS and 33 age-matched controls participated in this study. Women with PCOS were further divided into subgroups based on their PCOS phenotypes: phenotype A (n=35), phenotype B (n=33), phenotype C (n=31), and phenotype D (n=35).
Turk Thorac J
January 2020
Clinic of Biochemistry, Yenimahalle State Hospital, Ankara, Turkey.
Objectives: Emphysema and chronic bronchitis have different pathophysiologies but both are significant components of chronic obstructive lung disease (COPD). The levels of Matrix metalloproteinase (MMP)-9 in the bronchoalveloar lavage fluid (BALF) and in serum indicate the presence of emphysema. Intratracheal administration of elastase has been used to create a rat model of emphysema.
View Article and Find Full Text PDFJ Turk Ger Gynecol Assoc
June 2020
Department of Obstetrics and Gynecology, Acıbadem University Faculty of Medicine, İstanbul, Turkey
Objective: To investigate whether prior testis magnetic resonance spectroscopy predicts the success or failure of micro-dissection testicular sperm extraction (micro-TESE) in patients with non-obstructive azoospermia (NOA).
Material And Methods: Nine men with NOA who were scheduled for micro-TESE for the first time, 9 NOA men with a history of previous micro-TESE and 5 fertile men were enrolled. All NOA patients and fertile controls underwent testis spectroscopy.
J Clin Res Pediatr Endocrinol
March 2020
Katip Çelebi University Faculty of Medicine, Department of Pediatric Endocrinology, İzmir, Turkey
Objective: Turner syndrome (TS) is one of the most common chromosomal abnormalities and an important cause of short stature and infertility due to ovarian failure in females. The aim was to evaluate the knowledge of TS among physicians and parents of children with TS and to enhance awareness about this subject.
Methods: One hundred and forty physicians were included in the study.
Eurasian J Med
June 2019
Department of Microbiology, Mustafa Kemal University School of Medicine, Hatay, Turkey.
Objective: The aim of this study was to investigate the protective effects of the combined use of probiotic strains on the development of bacterial translocation in addition to liver and intestinal tissue damage due to biliary obstruction in rats.
Materials And Methods: Here, 3 groups each consisting of 10 rats were created:group 1 (sham group), group 2 (obstructive jaundice), and group 3 (obstructive jaundice+probiotic). Groups 1 and 2 were given 1 cc physiological saline solution by oral gavage twice a day; group 3 was given a probiotic solution that included Lactobacillus acidophilus, and microorganisms by oral gavage twice a day.
J Clin Res Pediatr Endocrinol
May 2019
İstanbul University İstanbul Faculty of Medicine, Department of Pediatric Nephrology, İstanbul, Turkey
Objective: Histopathological changes in the kidney in type 1 diabetes mellitus (T1DM) begin before detection of microalbuminuria. Therefore, there is interest in finding a better biomarker for the early detection of diabetic kidney injury. The aim of this present study was to determine whether urinary indicators of fibrosis are detectable early in the development of T1DM in children and if they may predict progressive renal injury.
View Article and Find Full Text PDFTurk J Obstet Gynecol
September 2018
University of Health Sciences, Antalya Training and Research Hospital, Clinic of Biochemistry, Antalya, Turkey.
Turk J Haematol
November 2018
Yıldırım Beyazıt University Faculty of Medicine, Department of Biochemistry, Ankara, Turkey
Objective: Sickle cell disease (SCD), described as a group of inherited blood disorders, affects millions of people throughout the world and is particularly common in the southern part of Turkey. We aimed to determine the relationship between ischemia-modified albumin (IMA) and the dynamic thiol/disulfide balance in SCD.
Materials And Methods: Fifty-four adult SCD patients and 30 healthy controls were included in the study.
Turk J Haematol
August 2018
Koç University Faculty of Medicine, Laboratory of Hemorheology, Hemodynamics, and Vascular Biology, İstanbul, Turkey
Objective: Hemorrhage is the leading cause of injury-related prehospital mortality. We investigated worst-case scenarios and possible requirements of the Turkish military. As we plan to use blood resources during casualty transport, the impact of transport-related mechanical stress on packed red blood cells (PRBCs) was analyzed.
View Article and Find Full Text PDFBalkan Med J
July 2018
Department of Biochemistry, Yıldırım Beyazıt University School of Medicine, Ankara, Turkey
Background: Oxidative stress has been proposed as a potential trigger in the etiopathogenesis of polycystic ovary syndrome-related infertility. Thiol/disulphide homeostasis, a recently identified oxidative stress marker, is one of the antioxidant mechanism in humans with critical roles in folliculogenesis and ovulation.
Aims: To investigate follicular fluid thiol/disulphide homeostasis in the etiopathogenesis of polycystic ovary syndrome and to determine its association with in vitro fertilization outcome.
J Turk Ger Gynecol Assoc
December 2017
Department of Obstetrics and Gynecology, Acıbadem University Faculty of Medicine, İstanbul, Turkey.
Objective: The study was planned to investigate whether DHEA supplementation had an impact on endometrial receptivity in women who were poor responders (POR).
Material And Methods: Twenty-eight POR women who were undergoing hysteroscopy and five fertile control subjects were included. The POR women were equally subdivided into two separate groups as patients who were currently using DHEA and those who were not.
Turk J Pharm Sci
December 2017
Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.
Objectives: Pycnogenol (PYC), a standardized extract from the bark of , consists of different phenolic compounds. PYC has shown to have protective effects on chronic diseases such as diabetes, asthma, cancer, and immune disorders. The aim of this study was to determine the effects of PYC against the DNA damage and biochemical changes in blood, liver, and lung tissues of ischemia-reperfusion (IR)-induced Wistar albino rats.
View Article and Find Full Text PDFTuberk Toraks
September 2017
Department of Chest Diseases, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
Introduction: To the best of our knowledge, no previous study regarding the serum telomerase levels in Maras powder users (MPUs) has been founded. The aim of the current study was to investigate serum telomerase levels in smokers and MPUs.
Materials And Methods: The study was carried out with 98 patients (36 MPUs, 32 smokers and 30 non-smokers).
Turk J Obstet Gynecol
March 2017
Selçuk University Faculty of Medicine, Department of Biochemistry, Konya, Turkey.
Objective: The two-step approach recommended by the National Diabetes Data Group (NDDG), Carpenter and Coustan (C&C), and O'Sullivan, and the single-step approach recommended by the International Association of Diabetes and Pregnancy Study Group (IADPSG) are used to diagnose gestational diabetes mellitus (GDM). We aimed to determine GDM prevalence and to compare the two-step and single-step approaches used in the southeastern region of Turkey.
Materials And Methods: In total, 3048 records of pregnant women screened for GDM between 2008 and 2014 were retrospectively extracted from our laboratory information system.
Acta Inform Med
June 2017
University of Pristine, Department of Nuclear medicine, Clinic of Biochemistry, Faculty of Medicine, Pristine, Kosovo.
Aim: The aim of this study was determination of validity of TcDTPA estimation of GFR for early detection of chronic kidney failure.
Material And Methods: There were 110 patients (54 males and 56 females) with kidney disease referred for evaluation of renal function at UCC of Kosovo. All patients were included in two groups.
J Craniofac Surg
October 2017
*Sisli Hamidiye Etfal Training and Research Hospital, Clinic of Otorhinolaryngology & Head and Neck Surgery †Sisli Hamidiye Etfal Training and Research Hospital, Clinic of Biochemistry, Istanbul, Turkey.
The relationship between intermittent nocturnal hypoxia and albuminuria in pediatric patients with adenotonsillar hypertrophy was evaluated in this prospective study. Fifty children with grade 3 to 4 adenotonsillar hypertrophy scheduled for adenoidectomy and/or adenotonsillectomy were selected for study group. Fifteen patients with adenotonsillar grade 1 to 2 or adenotonsillectomized subjects in a similar range of sex, age, and body mass index scheduled for other surgeries were selected for control group.
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