3 results match your criteria: "Clinic Center Hera[Affiliation]"

Could Kallikrein-Related Serine Peptidase 3 Be an Early Biomarker of Environmental Exposure in Young Women?

Int J Environ Res Public Health

August 2021

Andrology Unit and Service of Lifestyle Medicine in UroAndrology, Local Health Authority (ASL) Salerno, Coordination Unit of the network for Environmental and Reproductive Health (Eco-FoodFertility Project), "Ospedale San Francesco D'Assisi", Oliveto Citra, 84020 Salerni, Italy.

Article Synopsis
  • Bisphenols and phthalates impact androgen receptor signaling, which influences KLK3 secretion, suggesting environmental factors may affect this process.
  • A study measured serum KLK3 levels in healthy women from high and low environmental impact areas, finding higher levels in the high impact group, especially during ovulation.
  • Significant differences in KLK3 levels corresponded with lower progesterone levels in the high impact group during the luteal phase, indicating a potential link between environmental pollution and female reproductive health.
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Male infertility and the poor quality of sperm seem to be influenced by oxidative stress. In particular, the reactive oxygen species (ROS) mainly produced by morphologically altered spermatozoa affect sperm motility, morphology, and integrity. The aim of this study was to evaluate the efficacy of Myo-Inositol (Myo-Ins) on a number of parameters such as viscosity and total and progressive motility of spermatozoa, in order to better validate its possible practical application in vitro, in order to improve the capacitation protocols commonly used in Assisted Reproductive Technology (ART).

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