Possible link between the preferential unilateral chewing side and eruptive guidance of the maxillary canine germ : Cross-sectional study on panoramic radiographs.

Aim: To determine whether unilateral preferent chewing (UPC) affects the position and angulation of the permanent maxillary canine germ on the preferred side.

Materials And Methods: In a retrospective cross-sectional study, medical records from children 7.91(± 0.

Cross-Dehydrogenative Coupling of Secondary Amines with Silanes Catalyzed by Agostic Iridium-NSi Species.

An active catalytic system for the cross-dehydrogenative coupling (CDC) of a wide range of secondary amines with silanes is reported. The iridium(III) derivatives [Ir(H)(X)(κ-NSi)(L)] (NSi = {4,8-dimethylquinoline-2-yloxy}dimethylsilyl; L = coe, X = Cl, ; L = coe, X = OTf, ; L = PCy, X = Cl, ; L = PCy X = OTf, ), which are stabilized by a weak yet noticeable Ir···H-C agostic interaction between the iridium and one of the C-H bonds of the 8-Me substituent of the NSi ligand, have been prepared and fully characterized. These species have proven to be effective catalysts for the CDC of secondary amines with hydrosilanes.

An irreversible thermodynamic model of pre-biological small circular molecular dissipative structures inside vacuoles on the Archean Ocean surface.

A prebiotic model, based in the framework of thermodynamic efficiency loss from small dissipative eukaryote organisms [1-3], is developed to describe the maximum possible concentration of solar power to be dissipated on topological circular molecules structures encapsulated in lipid-walled vacuoles, which floated in the Archean oceans. By considering previously, the analysis of 71 species examined by covering 18 orders of mass magnitude from the Megapteranovaeangliae to Saccharomyces cerevisiae[2], suggest that in molecular structures of smaller masses than any living being known nowadays, the power dissipation must be directly proportional to the power of the photons of solar origin that impinge them to give rise to the formation of more complex self-assembled molecular structures at the prebiotic stage by a quantum mechanics model of resonant photon wavelength excitation. The analysis of 12 circular molecules (encapsulated in lipid-walled vacuoles) relevant to the evolution of life on planet Earth such as the five nucleobases, and some aromatic molecules as pyrimidine, porphyrin, chlorin, coumarin, xanthine, etc.

Macroplastic pollution in riparian corridors of urban and pristine mountain streams in Patagonia (Argentina).

Plastic pollution has garnered much more attention in marine environments, while scientific research on freshwater and terrestrial ecosystems has been relatively overlooked. Numerous studies worldwide have highlighted the presence of macroplastics (>2.5 cm) in mountain riverine environments, revealing that even these seemingly pristine ecosystems are not invulnerable to plastic contamination.

A long-term analysis, modeling and drivers of forest recovery in Central Mexico.

This study aims to evaluate the changes in forest cover from 1994 to 2015, identify the key drivers of forest recovery, and predict future trends. Using high-resolution remote sensing data, we mapped forest canopy density into detailed categories (closed > 50%, open 10-50%, and deforested < 10%) to differentiate processes like degradation, deforestation, densification, reforestation, and afforestation. A multinomial logistic regression was used to explore the relationship between the forest processes and socioeconomic, proximity, planning, and policy potential drivers.

Arsenic(V) and vanadium(V) fractionation after its incorporation into a sandy loam soil from Pampas region, Argentina.

Arsenic is a well-known toxic substance, widely distributed, whereas vanadium is a pollutant of emerging interest. Both have been found to correlate positively in groundwaters, thus concern arises on the effect of these pollutants on crops, if such waters are used for irrigation. We conducted a study on the effect of aging with a typical crop soil mimicking soils initially irrigated with water containing As and V.

Plate tectonics, cold adaptation and long-distance range expansion to remote archipelagos and the high Andes as drivers of a circumantarctic freshwater arthropod radiation.

Disjunct distributions, characterised by spatially separated populations of related species, offer insights into historical biogeographic patterns and evolutionary processes. This study investigates the evolutionary history of the diving beetle subfamily Lancetinae through a phylogenomic approach incorporating ultraconserved elements (UCEs) and heritage genetic markers. Our findings support an early Miocene origin for Lancetinae, with subsequent diversification influenced by historical vicariance events and long-distance dispersal.

Catalytic evaluation of microwave-assisted copper cobaltite oxide (CuCoO) for propane oxidation.

Attainment of a pristine copper cobaltite (CuCoO) phase by a fast and easy microwave (MW) assisted method is presented in this paper. The successful synthesis was supported by a series of characterization techniques, which confirmed the presence of a single phase and a possible inverted spinel crystal structure. Furthermore, catalytic performance evaluation of CuCoO in propane oxidation demonstrated its selectivity towards carbon dioxide (CO) formation, with negligible propanol production.

A practical method for the synthesis of small peptides using DCC and HOBt as activators in HO-THF while avoiding the use of protecting groups.

The synthesis of peptides in solution proceeds through successive steps involving the removal of a protecting group and the formation of the peptide bond. While most methodological efforts have focused on the development of new protecting groups and coupling agents, methodologies based on minimal protecting groups have been less explored. In this research, a peptide synthesis methodology was developed using DCC and HOBt in THF-HO, avoiding the use of protecting groups, reducing reaction times, and reusing HOBt during successive couplings.

Out-of-Equilibrium ceRNA Crosstalk.

Among non-coding RNAs, microRNAs are pivotal post-transcriptional regulators of gene expression in higher eukaryotes. Through a titration-based mechanism of interaction with their target RNAs, microRNAs can mediate a weak but pervasive form of RNA cross-regulation, as different endogenous RNAs can be effectively coupled by competing for microRNA binding (a phenomenon now known as "crosstalk"). Mathematical modeling has been proven of great help in unraveling many features of these competing endogenous RNA (ceRNA) interactions.

Disruption of cell wall and membrane integrity as antioomycete and antifungal mode of action by fusaric and 9,10-dehydrofusaric acids from endophytic fungus Fusarium lactis strain SME13-2.

Aims: This study aimed to assess the mode of action of fusaric and 9,10-dehydrofusaric acids on cell respiration by measuring the hyphal oxygen consumption rate, and the effects on cell membrane integrity by determining the electrical conductivity of the mycelium.

Methods And Results: Bioactivity-directed fractionation of the active culture medium and mycelium organic extracts from the Fusarium lactis strain SME13-2 isolated from Sapium macrocarpum, led to the isolation of two known alkylpicolinic acid derivatives: fusaric acid and 9,10-dehydrofusaric acid, along with the known polyketide bikaverin. Fusaric acid and 9,10-dehydrofusaric acid exhibited antioomycete and antifungal activities, significantly inhibiting the radial growth of Phytophthora capsici, Pythium aphanidermatum, Alternaria alternata and Fusarium oxysporum.

Oxidative Stress, Lysosomal Permeability, and Mitochondrial-Derived Vesicles Induced in NL-20 Human Bronchial Cells Exposed to Benzo[ghi]Perylene.

Benzo[ghi] perylene (b[ghi]p) is classified as non-carcinogenic to humans, and there are currently no occupational exposure models available to identify its effects. The aim of this work was to evaluate the effect of b[ghi]p on the lysosomes of NL-20 cells (a human bronchial cell line) exposed to 4.5 μM for 3 h.

Chronic cadmium exposure to minimal-risk doses causes dysfunction of epididymal adipose tissue and metabolic disorders.

Cadmium (Cd) is among the top seven most hazardous environmental contaminants. Minimal risk levels for daily exposure have been established, such as no observable adverse effect level (NOAEL) and lowest observable adverse effect level (LOAEL). Chronic exposure to Cd, at both NOAEL and LOAEL doses, causes toxicity in diverse tissues.

Cretaceous spreite-dominated ichnoassemblages in Antarctica.

This study investigates ichnoassemblages characterized by spreite trace fossils from the Upper Cretaceous Snow Hill Island Formation on Vega Island, Antarctica. The succession reveals alternating heterolithic beds of sandy siltstones to very fine- to fine-grained sandstones, suggestive of a deltaic depositional setting influenced by fluctuating energy conditions. The dominance of spreite structures, such as Paradictyodora antarctica and Euflabella, suggests the prevalence of a colonization window for deposit- or detritus-feeding activity.

Uterus transplants and Mexico's rule of law.

Uterus transplantation is a new fertility treatment for some women who lack a functioning uterus. The number of countries where these transplants are performed has steadily increased, and in Mexico, there is a growing interest in this procedure among patients, researchers, and clinicians. In this paper we look at Mexico and its legal system in order to determine what is the legal status of uterus transplants, and whether there is a right to them according to Mexican legislation.

Immature survival and female longevity of Aedes aegypti under natural winter conditions in the temperate region of Argentina.

The performance of Aedes aegypti was evaluated under natural winter nutritional and thermal conditions in the temperate region of Argentina. Immature stages were reared using leaf litter as a food source. The rearing was structured in three cohorts, the first started in late-fall, the second in early-winter and the last in mid-winter, and in each cohort two treatments were arranged according to solar exposure (sun and shade).

Characterization of the complete mitogenome data of collared peccary, (Linnaeus, 1758) (Suina: Tayassuidae) from Ucayali, Peru.

The collared peccary ( Linnaeus, 1758) is a vital resource for the subsistence and economy of the Amazonian inhabitants. Despite its importance, there is a notable lack of genetic information on Peruvian collared peccary populations. This study presents the complete mitogenome of from Peru, obtained by Illumina sequencing.

The Effect of μ-Limestone Additions on the Mechano-Chemical and Microstructural Properties of Slag and Binary Slag/Ground Fly Ash Alkaline-Activated Binders.

An alternative approach to reducing the clinker factor, i.e., worldwide CO emissions resulting from the production of composite cement, is to replace these materials with supplementary aluminosilicate-based materials that promote the formation of alkali-activated cements, whose elevated temperature resistance, limited permeability, strong binding properties, excellent durability, high chemical corrosion resistance, confinement of toxic waste, and environmentally low impact have attracted a lot of attention in the cement industry.

In Silico Hydrolysis of Lupin ( L.) Conglutins with Plant Proteases Releases Antihypertensive and Antidiabetic Peptides That Are Bioavailable, Non-Toxic, and Gastrointestinal Digestion Stable.

Lupin ( L.) proteins are potential sources of bioactive peptides (LBPs) that can inhibit dipeptidyl peptidase IV (DPP-IV) and angiotensin I-converting enzyme (ACE-I) activity. However, the capacity of different enzymes to release LBPs, the pharmacokinetic and bioactivities of the peptides released, and their binding affinities with the active sites of DPP-IV and ECA-I are topics scarcely addressed.

Antiprotozoal Activity Against and of Cyclopeptides Isolated from Saff.

Diseases caused by intestinal parasites such as protozoa represent a worldwide problem mainly for developing countries. From morbidity in different groups of people to cases of mortality in children and/or immunocompromised patients. In addition to the above, there is growing resistance to the drugs used in the treatment of these diseases, as well as undesirable side effects in patients.

Multiple Uses of Wild Edible Trees by a Nahua-Origin Community in Western Mexico.

Wild edible trees (WETs) play an important role in the diet of many rural communities. Therefore, research on their use and management is important to support both food sovereignty and local conservation of biocultural resources. We evaluated the different uses of WETs by the community of Zacualpan, Colima, in western Mexico, through 32 semi-structured interviews registering the species richness, plant parts consumed, and non-food uses.

Development, optimization and comparison of solid-liquid and liquid-liquid microextraction for the determination of four flavonols in Schinus molle L. using high-performance liquid chromatography coupled with second-order data modeling.

Flavonoids are particularly interesting because they have a broad spectrum of biological effects, including antioxidant and free radical scavenging activities. In this work, solid-liquid microextraction and dispersive liquid-liquid microextraction enhanced by ultrasound were developed and compared with the conventional method (Soxhlet extraction) to optimize the extraction of four flavonoids: rutin, quercitrin, quercetin, and myricetin in samples of Schinus molle (Aguaribay). During the development of the analytical method, different chemometric tools were used to optimize the microextraction procedure.

DensToolKit2: A comprehensive open-source package for analyzing the electron density and its derivative scalar and vector fields.

In this article, we provide details of the suite DensToolKit-v2, which consists of a set of cross-platform, optionally parallelized programs for analyzing the molecular electron density (ρ), as well as different fields and chemical indices derived from it. Notably, with this version, the user can compute the Non-Covalent Interaction index, the Density Overlap Regions Index, and fields related to single-spin-type molecular orbitals, such as the spin density. In addition, DensToolKit-v2 includes several programs for analyzing other less-known fields, such as the Density Matrix of order 1, the two-electron pair density function, and the Fourier transforms of these fields, that is, functionals in momentum space.