Lisch corneal dystrophy is genetically distinct from Meesmann corneal dystrophy and maps to xp22.3.

Purpose: There is an ongoing discussion whether Lisch corneal dystrophy (band-shaped and whorled microcystic dystrophy of the corneal epithelium) represents a disorder that is different from Meesmann corneal dystrophy. The purpose of this study was to evaluate at the molecular level if Lisch and Meesmann corneal dystrophies are genetically distinct.

Methods: We examined at the slit lamp a total of 48 members of a family with an aggregation of Lisch corneal dystrophy.