Effects of heat stress on growth performance, physiological responses, and carcass traits in broilers.

High environmental temperatures lead to metabolic changes, body weight reduction, and high mortality in chickens, affecting poultry production worldwide. This study aimed to evaluate the effects of heat stress, assessed by the temperature-humidity index (THI), on the growth performance, physiological response, carcasses, and hematological traits of broilers. A total of 200 broilers (between 17 and 31 days old) were kept in thermoneutral conditions (21 °C; 60% relative humidity, RH) for 3 days during the adaptation period, followed by 14 days of exposure to the experimental treatments.

Dietary Polycan, a β-glucan originating from SM-2001, attenuates high-fat-diet-induced intestinal barrier damage in obese mice by modulating gut microbiota dysbiosis.

Various metabolic diseases caused by a high-fat diet (HFD) are closely related to gut microbiota dysbiosis and epithelial barrier dysfunction. Polycan, a type of β-glucan, is effective in treating anti-obesity and metabolic diseases caused by HFD. However, the effect of Polycan on dysbiosis and epithelial barrier damage is still unknown.

Analysis of the impact and moderating effect of high-density development on urban flooding.

Although previous studies have posited that the high-density development of urban buildings and infrastructure contributes to urban flooding, empirical analyses and in-depth investigations into the interaction factors have remained limited. This study aims to analyze the influence and moderating effect of high-density development on urban flooding. Thus far, various land-use and interaction factors related to urban development density have been explored.

Synthesis and evaluation of tirbanibulin derivatives: a detailed exploration of the structure-activity relationship for anticancer activity.

Tirbanibulin, an FDA-approved microtubule-targeting agent (MTA) introduced in 2020, represents a pioneering treatment for precancerous actinic keratosis. Despite its failure to gain approval as an anticancer agent due to insufficient efficacy, there remains potential value in extending its application into malignancy treatment through tirbanibulin-based derivatives. Tirbanibulin possesses a distinctive dual mechanism of action involving microtubule and Src inhibition, distinguishing it from other MTAs.

Successful treatment of facet joint synovial cyst through percutaneous rupture: a case report.

Facet joint synovial cysts can cause significant back pain and radiculopathy. Treatment options for symptomatic facet joint synovial cysts include surgical excision, facet joint steroid injections, and cyst aspiration. Herein, we report our experience of successfully rupturing a lumbar facet joint synovial cyst through a percutaneous approach with two needles using forceful pressure under C-arm fluoroscopic guidance.

Nationwide Trends in Osteoporosis in Koreans With Disabilities From 2008 to 2017.

This study examined the 10-year trends in the prevalence of osteoporosis according to disability grade and type compared with those without disabilities in South Korea. We linked national disability registration data with the National Health Insurance claims data. Age- and sex-standardized prevalence of osteoporosis were analyzed from 2008 to 2017 according to sex, disability type, and disability grade.

Morphology-dependent adsorption energetics of Ru nanoparticles on hcp-boron nitride (001) surface - a first-principles study.

Active B-sites on Ru catalysts can be exploited for various catalytic applications; in particular, the epitaxial formation of Ru nanoparticles with hexagonal planar morphologies on hexagonal boron nitride sheets increases the number of active B-sites along the nanoparticle edges. The energetics of adsorption of Ru nanoparticles on hexagonal boron nitride were investigated using density functional theory calculations. Then, to understand the fundamental reason for this morphology control, adsorption studies and charge density analysis were performed on fcc and hcp Ru nanoparticles heteroepitaxially formed on a hexagonal boron nitride support.

Severity of myxomatous mitral valve disease in dogs may be predicted using neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratio.

Objective: To investigate the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) in dogs with myxomatous mitral valve disease (MMVD).

Animals: 106 dogs with MMVD and 22 healthy dogs were included in the study.

Procedures: CBC data were obtained retrospectively, and NLR, MLR, and PLR were compared between dogs with MMVD and healthy dogs.

Magnetocaloric effect and Griffiths phase analysis in a nanocrystalline HoNiMnO and HoCoMnO double perovskite.

Rare-earth double perovskite oxides have intriguing magnetocaloric properties at cryogenic temperatures. In this study, HoNiMnO and HoCoMnO were synthesized using the sol-gel method, which crystallized in a monoclinic structure in the 2/ space group. The magnetic phase transition was observed at 81.

Towards hard-magnetic behavior of CoFeO nanoparticles: a detailed study of crystalline and electronic structures, and magnetic properties.

We have used the coprecipitation and mechanical-milling methods to fabricate CoFeO nanoparticles with an average crystallite size () varying from 81 to ∼12 nm when changing the milling time ( ) up to 180 min. X-ray diffraction and Raman-scattering studies have proved the samples crystalizing in the spinel structure. Both the lattice constant and residual strain tend to increase when () increases (decreases).

 (Balsaminaceae), a new species from South Korea.

A new species from Gangwon-do, South Korea, is described and illustrated, based on its morphology and distribution. is different from , another similar species in South Korea, in some ways: possesses a serrate leaf margin with flat tooth tip, while possesses a crenate leaf margin with erect tooth tip; it has an erect inflorescence, while has a pendulous inflorescence; it has a smaller flower which is 2-2.6 cm long, while has a flower of 2.

Two new endemic species, and (Apiaceae), from Korea.

Two new species of (Apiaceae), and , from Gangwon Province, South Korea, are described. Both species are most similar to and because of their linear ultimate leaf segments. was found on crevices of rocks in mountain summits and can be distinguished by its pubescent ovary, purple anthers, oblong schizocarp, and 1 or (2) vittae per vallecula and 4 on the commissural face.

Impact of aza-substitutions on the preference of helix handedness for β-peptide oligomers: a DFT study.

We studied the helix preference of the heterochiral pentamers of -2-aminocyclohexanecarboxylic acid (-ACHC) and -2-aminocyclopentanecarboxylic acid (-ACPC) with alternating backbone configurations by replacing C-aza- or C-aza-peptide residues using DFT methods in solution. The helix-handedness preferences of two pentamers were strongly affected by the replacement positions (, chiralities) but not depending on the solvent polarity.

Flavone-associated resistance of two species to duckweed weevil attack.

and are free-floating plants that often live in the same habitat. However, little is known about how they differ in response to herbivore attacks. In this study, we examined the species-specific resistance of two species to the duckweed weevil, .

Biological activities of sweet potato ( L.) tips and tubers.

This study was conducted to evaluate the biological activities of sweet potato tips and tubers. Antioxidant activity of 2,2-azino-bis 93-ethlbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities had the highest value of 32.45 mg, AAE/g, and 15.

Jejuketomycins A and B, polyketide glycosides with cancer cell migration inhibitory activity from sp. KCB15JA151.

Two new polyketide glycosides jejuketomycins A (1) and B (2), were isolated from a culture of sp. KCB15JA151. Their chemical structures including the absolute configurations were determined by detailed analyses of the NMR and HRMS data and ECD calculations and spectral data.

Genetic differentiation that is exceptionally high and unexpectedly sensitive to geographic distance in the absence of gene flow: Insights from the genus in East Asian regions.

Genetic differentiation between populations is determined by various factors, including gene flow, selection, mutation, and genetic drift. Among these, gene flow is known to counter genetic differentiation. The genus , an early flowering perennial herb, can serve as a good model to study genetic differentiation and gene flow due to its easily detectable population characteristics and known reproductive strategies, which can be associated with gene flow patterns.

One-pot, ligand-free, room-temperature synthesis of Au/Pd/ZnO nanoclusters with ultra-low noble metal loading and synergistically improved photocatalytic performances.

Au/Pd/ZnO nanoclusters with ultra-low noble metal loadings were prepared by a one-step and ligand-free method at room temperature. HRTEM, ICP-MS, XPS, and elemental mapping analysis confirmed that the obtained Au/Pd/ZnO nanoclusters were composed of ZnO nanoclusters decorated with well-dispersed AuPd nanoparticles. Au/Pd/ZnO nanoclusters exhibited higher photocatalytic activity compared with those of pristine ZnO, Au/ZnO and Pd/ZnO.

Jejucarbazoles A-C, carbazole glycosides with indoleamine 2,3-dioxygenase 1 inhibitory activity from sp. KCB15JA151.

A bioassay-guided investigation led to the isolation of three new carbazole glycosides, jejucarbazoles A-C (1-3), from sp. KCB15JA151. Their planar structures were elucidated by detailed NMR and MS spectroscopic analysis with a literature study.

Development of curcumin-loaded gum nanoparticles: Synthesis, characterization, control release behavior, and evaluation of anticancer and antimicrobial properties.

The present work was conducted to develop a new polysaccharide-based encapsulation system via electrostatic interactions between  gum exudates (PAGE) and Ca ions to enhance the biological activity and bioavailability of curcumin. The effects of different levels of pH (6, 7, and 8) and ion concentrations (1, 3, and 5) on the particle diameter and surface charge of the samples were examined. The encapsulation efficiency in the PAGE-based nanoparticles was realized to be 86.

L. flower extract inhibits cell growth and metastatic properties in human colon and lung cancer cell lines.

Snapdragon L.) flowers are one of the most frequently used edible flowers in different preparations of foods and drinks. In this study, we examined inhibitory effects of snapdragon flower extract (SFE) against distinctive properties of cancer cells, stimulated growth, and activated metastasis, using H1299 lung cancer and HCT116 colon cancer cell lines.

Strong correlation between flux pinning and epitaxial strain in the GdBaCuO /LaSrMnO nanocrystalline heterostructure.

The effect of magnetic flux pinning is investigated in GdBaCuO (GdBCO) thin films with two different types of ferromagnetic LaSrMnO (LSMO) buffers (nanoparticles and a layer) deposited on an STO substrate. Magnetization analyses reveal the presence of multiple flux pinning mechanisms responsible for the improvement in the critical current density of GdBCO films. While core pinning becomes a dominant pinning mechanism in GdBCO films with LSMO nanoparticles, a hybrid effect of magnetic-volume and core-point pinning is observed in GdBCO films with LSMO layers.

(Saxifragaceae), a new species from South Korea.

A new species B.U.Oh & H.