4,001 results match your criteria: "Chung-ang University College of Medicine[Affiliation]"

Strain CAU 1644 was isolated from sea sand at Ganghwa Island, Republic of Korea. The bacterium is aerobic, Gram-staining negative, yellow-colored, non-motile, catalase-positive, and rod-shaped. Cells of strain CAU 1644 grew at 20-40 °C and pH 6.

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Introduction: Pulmonary vein isolation (PVI) by cryoballoon ablation (CBA) is considered an effective primary strategy for early persistent atrial fibrillation (AF). However, data regarding CBA for long-standing persistent AF (PeAF) are limited. We evaluated the efficacy and safety of CBA for long-standing PeAF compared to PeAF.

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Purpose: To compare clinical and radiologic outcomes between biceps anchor tenodesis (AT), biceps soft-tissue tenodesis (ST), and biceps tenotomy (TT) for patients with concomitant rotator cuff repair (RCR).

Methods: This retrospective study reviewed patients who underwent arthroscopic RCR for full-thickness rotator cuff tears with AT, ST, or TT with minimum 2-year follow-up. All biceps procedures were performed arthroscopically, and ST consisted of fixation to the transverse humeral ligament.

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Article Synopsis
  • A study investigated the risk factors for anterior knee pain (AKP) after total knee arthroplasty (TKA) in 284 patients, focusing on various preoperative measurements to understand their impact on surgical outcomes.
  • The research found significant differences in key radiographic angles, particularly the patellar tilt and trochlear dysplasia indexes, between patients with and without AKP after TKA.
  • Researchers concluded that attention should be given to certain preoperative measurements, as they may increase the risk of experiencing AKP post-surgery.
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Evolution of characteristics of MASLD with and without diabetes: a meta-analysis of placebo arms.

Sci Rep

November 2024

Department of Internal Medicine, College of Medicine, Ewha Womans University, 1071 Anyangcheon-ro, Yangcheon-gu, Seoul, 07985, Korea.

Background: We explored the changes in metabolic dysfunction-associated steatotic liver disease (MASLD) severity over time by analyzing data from the placebo arms of randomized controlled trials (RCTs), focusing on the presence of diabetes.

Methods: RCTs on MASLD that included a placebo arm were identified using a systematic search of the literature. Primary outcomes were changes in hepatic steatosis and fibrosis.

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Objectives: This study evaluated the association between serum albumin levels and coronary artery calcification (CAC) progression in asymptomatic adults without hypoalbuminaemia at baseline.

Design: Observational cohort study.

Setting: Data from the Korea Initiatives on Coronary Artery Calcification (KOICA) which is a retrospective, single ethnicity, multicentre and observational registry were analysed.

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Article Synopsis
  • - A study was conducted to assess the effectiveness and safety of single-port transoral robotic surgery (SP TORS) for treating tongue base resection in patients with obstructive sleep apnea (OSA), involving 25 patients over 16 months.
  • - The results showed a 76% success rate in reducing apnea-hypopnea index (AHI) scores from an average of 58.56 down to 18.19, with improvements in symptoms like foreign body sensation and taste dysfunction within three months.
  • - Although there were some major complications, including hemorrhage in 8% of patients, the procedure demonstrated significant benefits compared to traditional methods, suggesting the need for more research in this area.
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Sex difference in the risk of coronary artery calcification progression related to hyperuricemia among asymptomatic 12,316 Korean adults.

Sci Rep

November 2024

Division of Cardiology, Severance Cardiovascular Hospital, Yonsei-Cedars-Sinai Integrative Cardiovascular Imaging Research Center, Yonsei University College of Medicine, Yonsei University Health System, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Data on hyperuricemia-related changes in coronary atherosclerosis are limited, especially in sex difference. This study evaluated the association between hyperuricemia and coronary artery calcification (CAC) progression in asymptomatic Korean men and women. We analysed the data of 12,316 asymptomatic adults (51.

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Background: Both insulin resistance and hyperglycemia are important risk factors for atherosclerosis. While the characteristics of atherosclerosis are obviously different according to established diabetes, little has been known regarding the risk of coronary artery calcification (CAC) progression related to the biomarkers of atherogenic index of plasma (AIP), triglyceride glucose (TyG) index, and hemoglobin A1C (HbA1C) in conditions with and without diabetes.

Methods: We analyzed 12,326 asymptomatic Korean adults (mean age 51.

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Corneal steep island formation after primary pterygium surgery.

PLoS One

November 2024

Department of Ophthalmology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Republic of Korea.

Article Synopsis
  • The study investigates the formation of corneal steep island (CSI) after primary pterygium surgery and seeks to identify preoperative features of pterygium that may predict CSI likelihood.
  • A total of 93 eyes from 84 subjects undergoing combined pterygium excision and conjunctival-limbal autograft were analyzed to compare outcomes between those with and without postoperative CSI.
  • Results indicated that CSI occurred in 28% of cases, with significant differences in preoperative corneal astigmatism and pterygium morphology, suggesting that certain characteristics may increase the risk for CSI post-surgery.
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Background: Red blood cells (RBCs) are a limited resource, and the adverse effects of transfusion must be considered. Multiple randomized controlled trials on transfusion thresholds have been conducted, leading to the establishment of a restrictive transfusion strategy. This study aimed to investigate the status of RBC transfusions in critically ill patients.

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Calcium channel blockers (CCBs) are frequently co-administered with clopidogrel in cardiovascular disease. Although an inhibitory drug interaction exists between them, comprehensive large-scale studies for its validation are lacking. We investigated interactions between CCBs and clopidogrel using a large-scale national registry of patients who underwent percutaneous coronary intervention (PCI).

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Background: Cumulative evidence consistently shows that anthropometric and body composition measurements are strongly linked to the risk of incident diabetes, typically based on baseline measurements. This study aims to assess whether repeated measurements enhance the prediction of diabetes risk beyond baseline assessments alone.

Methods: We utilized data from a 16-year population-based follow-up cohort within the Korean Genome and Epidemiology Study, comprising 6,030 individuals aged 40 to 69 years at baseline.

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The optimal energy level of virtual monochromatic imaging in dual-energy CT arthrography of the wrist.

Br J Radiol

February 2025

Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, 06973, Republic of Korea.

Objectives: To suggest an optimal energy level of virtual monochromatic images (VMIs) in dual-energy CT (DECT) arthrography of the wrist.

Methods: This retrospective study included 53 patients with wrist CT arthrography. Conventional polychromatic images and VMIs at 4 energy levels (40-70 keV at 10 keV intervals) were obtained.

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Article Synopsis
  • The study focuses on the increasing use of the DIEP flap for breast reconstruction and highlights the development of 3D models to aid in the surgical dissection process.
  • Collaboration among surgeons, radiologists, and 3D model makers was crucial in creating an accurate and user-friendly 3D DIEP model that can be accessed online via mobile devices.
  • The resulting 3D model improved visual clarity of vascular structures and allowed for personalized adjustments, ultimately making surgeries safer and easier, especially for less experienced surgeons.
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Background: Recently, cough reflex hypersensitivity has been proposed as a common underlying feature of chronic cough in adults. However, symptoms and clinical characteristics of cough hypersensitivity have not been studied amongst phenotypes of chronic cough. This study aimed to compare symptom features, such as cough triggers and associated throat sensations, of cough hypersensitivity in patients with asthmatic chronic cough and those with refractory chronic cough (RCC).

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Neural network-based automated proptosis measurement using computed tomography images for patients with thyroid-associated orbitopathy.

Sci Rep

November 2024

Department of Ophthalmology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, 102 Heukseok-ro, Dongjak-gu, Seoul, 06973, South Korea.

The purpose of this study was to evaluate the clinical feasibility and reliability of a neural network (NN)-based automated proptosis measurement system using computed tomography (CT) images. An automated proptosis measurement system was developed using the CT images of 200 eyes from 100 patients diagnosed with thyroid-associated orbitopathy. We compared the proptosis value obtained from the proposed automated system with the values obtained from the Hertel exophthalmometer and manual measurements of CT slices.

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Background: The incidence of hypotension in parturients with coronavirus disease (COVID-19) undergoing regional anesthesia remains controversial. This study aimed to investigate the incidence of hypotension during spinal anesthesia in parturients infected with COVID-19, as well as to identify associated risk factors.

Methods: This retrospective study compared COVID-19-positive parturients who underwent cesarean section under spinal anesthesia (COVID-19 group) with a control group between January 2017 and June 2022.

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The LabGenius C-CT/NG-BMX assay (LabGenius CT/NG; BIOMEDUX, Gyeonggi, Republic of Korea) is a recently developed real-time PCR assay that can simultaneously detect the sexually transmitted pathogens (CT) and (NG) in genitourinary specimens. We evaluated the analytical performance of this assay in comparison with BD MAX CT/GC/TV (Becton Dickinson, Franklin Lakes, NJ, USA). The results of both assays were in nearly perfect agreement for the detection of CT and NG.

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Article Synopsis
  • * Out of 170,226 patients, only 3361 (1.97%) received APDs, and overall findings showed that APD use was linked to higher mortality rates among these patients, including those without metastasis.
  • * Interestingly, patients with a prior psychiatric history and long-term APD use had lower mortality, while those starting APDs during radiotherapy experienced higher mortality, indicating that the reasons for APD use may play a significant role in patient outcomes.
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Background And Purpose: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted people's lifestyles, changing sleep patterns. This study investigated changes in sleep patterns and disturbances in South Koreans over the past decade, including during the pandemic.

Methods: We compared data from the Korean Sleep Headache Society Phase I survey (n = 2484; conducted in 2010) and the National Sleep Survey of South Korea 2022 (n = 3729; conducted in 2022), involving participants aged 20-69 years.

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Background/aims: We previously reported that patients with moderate-to-severe ulcerative colitis (UC) often experience common mental disorders (CMDs) such as anxiety and depression, necessitating immediate psychological interventions within the first 4 weeks of diagnosis. In this 3-year follow-up study of the MOSAIK cohort in Korea, we examined the effects of CMDs at initial diagnosis on clinical outcomes and health-related quality of life (HRQoL).

Methods: We examined differences in clinical outcomes (evaluated based on clinical response, relapse, hospitalization, and medication use) and HRQoL (assessed using the Inflammatory Bowel Disease Questionnaire [IBDQ] and Short Form 12 [SF-12]) according to Hospital Anxiety and Depression Scale (HADS) scores at diagnosis.

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Backgruound: Medullary thyroid carcinoma (MTC) has a poorer prognosis than differentiated thyroid cancers; however, comprehensive data on the long-term outcomes of MTC remain scarce. This study investigated the extended clinical outcomes of MTC and aimed to identify prognostic factors.

Methods: Patients diagnosed with MTC between 1980 and 2020 were retrospectively reviewed.

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