195 results match your criteria: "Chukwuemeka Odumegwu Ojukwu University; Imo State University[Affiliation]"

Objectives: This research explores the perceptions of medical students regarding self-assessment techniques in clinical studies at public universities in Anambra State, Nigeria. Specifically, it investigates the benefits of these techniques and their perceived alignment with formal evaluations conducted by supervisors.

Methods: Utilizing a descriptive cross-sectional study design, data were collected from 273 consenting medical students through an online questionnaire.

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Objectives: Transfusion-transmitted infections are a serious complication of blood transfusion. Devising a means of detecting at-risk blood donors may be beneficial in low- and middle-income countries such as Nigeria. We sought to determine the impact of ABO blood group on the prevalence of transfusion transmitted infections.

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Article Synopsis
  • The study compares outcomes of left atrial appendage closure combined with catheter ablation (LAACCA) vs. catheter ablation alone in patients with atrial fibrillation and heart failure.
  • Results show that LAACCA leads to longer hospital stays, higher mortality rates, and increased hospitalization costs compared to catheter ablation alone.
  • Post-procedure complications were also more common in the LAACCA group, including higher rates of myocardial ischemia and complete atrioventricular block.
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Nitrate contamination in drinking water poses significant health risks, particularly in rapidly urbanizing areas of developing countries. This study presents an integrated computational and graphical approach to evaluate the geochemistry and health risks of nitrate-contaminated water for six age groups in Southeast, Nigeria. The research employed a detailed methodology combining water nutrient pollution index (WNPI), nitrate pollution index (NPI), water pollution index (WPI), geochemical plotting techniques, stoichiometry, and health risk computations.

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Background: Colorectal cancer screening has been shown to be effective in reducing the burden of colorectal cancer. However, the screening rate has been suboptimal, and mortality due to colorectal cancer remains high. With the presence of proactive prevention strategies, low screening rates could still be due to individual factors.

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Bisphenol A (BPA) is a vital raw material used to manufacture various household and commercial goods. However, BPA is a contaminant of emerging concern (CEC) and an endocrine-disrupting chemical (EDC) capable of migrating and bio-accumulating in environmental and biological compartments. At threshold levels, they become toxic causing adverse health and environmental issues.

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  • Rapid population growth and industrialization in urban areas are significantly degrading water quality, particularly in the Doon Valley region of the Garhwal Himalaya.
  • Groundwater samples were tested for six toxic elements, with results indicating that although the levels were below safe limits, molybdenum and nickel were the most concentrated elements detected.
  • Machine learning models, especially the radial basis function neural network, showed strong accuracy in predicting various water quality indices related to heavy metals, although the multilayer perceptron model exhibited more variability in its predictions.
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Background This study analyzed the incidence, characteristics, and mortality risk associated with cryptogenic organizing pneumonia (COP) among hospitalizations for systemic lupus erythematosus (SLE) with lung involvement. Methods Adult hospitalizations from the 2016-2020 nationwide inpatient sample were analyzed using relevant International Classification of Diseases (ICD)-10 codes for SLE with lung involvement (M32.13) and COP (J84.

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Background: Cardiovascular diseases (CVDs), a significant global health concern, are responsible for 13% of all deaths particularly in Africa, where they contribute substantially to the global disease burden, taking several millions of lives globally and annually. Despite advancements in healthcare, the burden of CVDs continues to rise steadily. This comprehensive review critically examines the intersection of artificial intelligence (AI) and cardiovascular disease (CVD) management in Africa.

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Objective: Tenofovir alafenamide (TAF)-based antiretroviral therapy (ART) regimens have been associated with adverse changes in lipid and glucose profiles compared with tenofovir disoproxil fumarate (TDF)-based ART, but data in pregnancy is limited. We evaluated metabolic markers in pregnant women with HIV after starting TAF- vs TDF-based ART.

Methods: We analyzed data within the IMPAACT 2010/VESTED trial, which demonstrated better pregnancy outcomes in pregnant women randomized to initiate TAF/Emtricitabine/Dolutegravir (TAF/FTC+DTG; n=217) or TDF/FTC+DTG (n=215).

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Background: Construct validation of cognitive batteries across Africa is imperative to understanding dementia in the region. We examined construct validity and internal consistency of the neuropsychological battery of Uniform Data Set version 3 (UDSNB 3.0) of the Alzheimer Coordinating Center in Nigeria older adults.

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Article Synopsis
  • * Out of 293 children, most cases were found to be cancerous, with non-Hodgkin lymphoma being the most common type, and the average age of diagnosis was 12 years.
  • * The research showed that many kids with malignant tumors stopped their treatment compared to those with benign ones, and it suggests that better strategies are needed to help kids stick to their treatment, taking into account their age and gender.
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  • Carbamazepine, an antiepileptic drug, can cause hiccups in some patients, with incidence rates between 2.5% and 40%, despite being a relatively uncommon side effect.
  • This side effect can significantly disrupt sleep, social functioning, and overall quality of life, highlighting its importance in clinical practice.
  • Effective management involves a team approach with neurologists and pharmacists, focusing on strategies like dose adjustments and alternative therapies to alleviate the hiccups and improve patient well-being.
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Oxidative stress-related pathologies have guided the scientific community into delving into natural product-based research on plant-based metabolites. Plant secondary metabolites serve as a valid alternative in managing oxidative stress-related pathologies. In this study, we present the secondary metabolite constituents of the polar extract (PE) and nonpolar extract (NPE) from the leaves of .

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Objective: To assess the uptake of a multidisciplinary team approach in obstetric disseminated intravascular coagulopathy (DIC) management in a low- to middle-income country.

Methods: A cross-sectional observational study, in which a semi-structured and pre-tested questionnaire was used to collect data on the uptake by Nigerian obstetricians of the multidisciplinary team approach to obstetric DIC management.

Results: A total of 171 obstetricians responded, 82 (48.

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Background: Sickle cell anaemia (SCA) imposes a substantial healthcare burden, affecting millions of people worldwide. Understanding the determinants influencing SCA severity is crucial for enhanced disease management and optimized patient outcomes. This study aimed to investigate the relationship between Neutrophil-Lymphocyte Ratio (NLR), Platelet-Neutrophil Ratio (PNR), Platelet-Lymphocyte Ratio (PLR), and SCA severity.

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The potentials of mesoporous TiO-ZnO (3TiZn) were explored on photocatalytic degradation of doxycycline (DOX) antibiotic, likewise the influence of adsorption on the photocatalytic process. The 3TiZn was characterized for physical and chemical properties. Stability, reusability, kinetic and the ability of 3TiZn to degrade high concentration of pollutant under different operating conditions were investigated.

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Water resources are constantly threatened by pollution of potentially toxic elements (PTEs). In efforts to monitor and mitigate PTEs pollution in water resources, machine learning (ML) algorithms have been utilized to predict them. However, review studies have not paid attention to the suitability of input variables utilized for PTE prediction.

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Objective: To examine the prevalence, perinatal outcomes and factors associated with neonatal sepsis in referral-level facilities across Nigeria.

Design: Secondary analysis of data from the Maternal and Perinatal Database for Quality, Equity and Dignity Programme in 54 referral-level hospitals across Nigeria.

Setting: Records covering the period from 1 September 2019 to 31 August 2020.

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Groundwater, a predominant reservoir of freshwater, plays a critical role in providing a sustainable potable water and water for agricultural and industry uses in the In Salah desert region of Algeria. This research collected 82 underground water samples from Albian aquifers to assess water quality and identify hydrogeochemical processes influencing mineralization. To achieve this objective, various methods were employed to evaluate water quality based on its intended uses.

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Objective: To determine the incidence and sociodemographic and clinical risk factors associated with birth asphyxia and the immediate neonatal outcomes of birth asphyxia in Nigeria.

Design: Secondary analysis of data from the Maternal and Perinatal Database for Quality, Equity and Dignity Programme.

Setting: Fifty-four consenting referral-level hospitals (48 public and six private) across the six geopolitical zones of Nigeria.

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