9,126 results match your criteria: "Chronic Granulomatous Disease"
J Am Dent Assoc
December 2024
Background: The authors reviewed a case involving the orofacial manifestations of Crohn disease (CD) in an adolescent whose treatment was ultimately managed with a newer class of biologic drug agent, ustekinumab (Stelara, Janssen Biotech). CD is a chronic inflammatory condition affecting the gastrointestinal tract that often causes extraintestinal complications. The underlying etiology of CD involves genetic, environmental, and local factors.
View Article and Find Full Text PDFIr J Med Sci
December 2024
Rheumatology Department, Gülhane Training and Research Hospital, University of Health Sciences Turkey, Ankara, Turkey.
Background: Idiopathic granulomatous mastitis (IGM) is a benign and rare chronic inflammatory disease of the breast. Although there are various treatment modalities, an ideal treatment algorithm has not been defined.
Aims: We designed this study to evaluate the clinical status, duration of remission, remission rates, and treatment algorithm in patients with IGM during a 5-year follow-up period after immunosuppressive therapy.
Cureus
November 2024
Dermatology, University of California Davis Medical Center, Sacramento, USA.
Chromoblastomycosis is an uncommon, chronic granulomatous fungal infection of the skin and subcutaneous tissue. Chromoblastomycosis is most commonly caused by the traumatic inoculation of dematiaceous (pigmented) fungi, most commonly species, species, and species. Chromoblastomycosis usually affects agricultural workers in tropical and subtropical climates.
View Article and Find Full Text PDFJ Surg Case Rep
December 2024
Department of Otolaryngology Head and Neck Surgery, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is a type of invasive fungal rhinosinusitis that is characterized by the presence of pathologic findings of non-caseating granulomas in the paranasal sinuses. This article describes two cases of CGIFRS with fatal outcomes. The first case was for a 36-year-old man who presented with headache, dizziness, and vomiting for 1 month.
View Article and Find Full Text PDFBackground: The transition to adult health care is challenging for adolescents and young adults (AYA) with Chronic Granulomatous Disease (CGD). This pilot study aimed to facilitate the learning of AYA with CGD about their health care and to aid in the development of life skills to enhance self-care.
Methods: AYA and caregivers (for participants <18 years of age) completed an adapted Transition Readiness Assessment.
Front Vet Sci
November 2024
Departamento de Sanidad Animal, Instituto de Ganadería de Montaña (IGM) CSIC-ULE, León, Spain.
Paratuberculosis is a chronic granulomatous enteritis, caused by subspecies (), that affects ruminants worldwide. Vaccination has been considered the most cost-effective method for the control of this disease in infected dairy herds. However, currently available vaccines do not provide complete protection and interfere with the diagnosis of both paratuberculosis and bovine tuberculosis, limiting its use.
View Article and Find Full Text PDFJ Rhinol
July 2024
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Tuberculosis of the paranasal sinus is a rare disease caused by infection with Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis. Although the worldwide incidence of tuberculosis is declining, the diagnosis of primary paranasal tuberculosis remains challenging and cannot be ruled out in patients presenting with refractory chronic rhinosinusitis after adequate surgical and medical treatment. We experienced a case of paranasal tuberculosis with no evidence of previous tuberculosis infection.
View Article and Find Full Text PDFFukushima J Med Sci
December 2024
Department of Pediatrics, Japan Self Defense Forces Central Hospital.
Acute pancreatitis in children in Japan is often caused by an anatomical abnormality of the pancreatic and bile duct, resulting in fever, abdominal pain, vomiting, diarrhea, and other symptoms. Crohn's disease, however, is a chronic granulomatous inflammatory bowel disease with ulcerative lesions of the intestinal tract of unknown cause that occurs mainly in young people, with symptoms similar to those of acute pancreatitis. We report a case of acute pancreatitis diagnosed in a patient not only with incomplete fusion of the pancreatic duct but also with Crohn's disease.
View Article and Find Full Text PDFInfez Med
December 2024
Infectious Disease Division, Department of Internal Medicine, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, & King Fahad hospital of the University, Al-Khobar, Saudi Arabia.
Leprosy, a chronic infectious disease caused by complex, remains a significant global health concern despite being curable with multidrug therapy. Delayed diagnosis is common, particularly in non-endemic regions or when presenting with atypical symptoms. This can lead to missed opportunities for early intervention, potential disabilities, and increased transmission.
View Article and Find Full Text PDFSarcoidosis Vasc Diffuse Lung Dis
December 2024
Pulmonology department, Hedi Chaker university hospital, Faculty of Medicine of Sfax. Sfax University.
Background And Aim: Sarcoidosis is a systemic disease of unknown cause characterized by the formation of non-caseating granulomatous inflammation in various organs, mainly lungs and intrathoracic lymph nodes. Its clinical and paraclinical presentation can vary from mild to life-threatening. Our objective is to study the clinical, paraclinical and evolution profile of mediastino-pulmonary sarcoidosis.
View Article and Find Full Text PDFPediatr Allergy Immunol
December 2024
Division of Immunology and the Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
J Investig Med High Impact Case Rep
December 2024
College of Medicine, University of Baghdad, Baghdad, Iraq.
This case report underlines the diagnostic and therapeutic dilemmas in a 19-day-old neonate who had presented with features suggestive of chronic granulomatous disease (CGD). The baby had a history of fever, lethargy, and masses on the skin, for which an extensive diagnostic workup was needed to rule out infective etiology given no improvement with initial empiric therapy. Laboratory investigations, including imaging and genetic studies, confirmed the diagnosis of CGD.
View Article and Find Full Text PDFBladder (San Franc)
November 2024
Department of Pathology and Laboratory Medicine, Brantford General Hospital, Brantford, Ontario N3R 1G9, Canada.
Background: Malakoplakia is a rare granulomatous disease that commonly involves the genitourinary tract with the urinary bladder being the most frequently affected site. It is characterized by histiocytes containing distinct basophilic calcified inclusions called Michaelis-Gutmann bodies. It is believed to result from abnormally functioning macrophages, with inclusions representing calcifications around incompletely digested bacteria.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2024
Anhui Province Key Laboratory of Animal Nutritional Regulation and Health, Anhui Science and Technology University, Fengyang, China.
BMC Vet Res
December 2024
Chemical and Veterinary Investigation Office Westphalia, Arnsberg, Germany.
Background: Paratuberculosis, caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic granulomatous enteritis that affects domestic and wild ruminants and camelids. The disease has rarely been reported in alpacas in Germany. This publication describes epidemiologically independent cases of paratuberculosis in two alpacas in Germany.
View Article and Find Full Text PDFCureus
October 2024
Radiodiagnosis, All India Institute of Medical Sciences, Deoghar, Deoghar, IND.
Curr Opin Hematol
January 2025
Instituto de Pesquisa Pele Pequeno Principe/Faculdades Pequeno Principe, Hospital de Clinicas da Universidade Federal do Parana, Curitiba, Brazil.
Purpose Of Review: Hematopoietic stem cell transplantation (HSCT) and inborn errors of immunity (IEI) have been closely linked since transplantation was first used to cure severe combined immunodeficiency (SCID) in 1968. Since then, novel genes and diseases have been continually added to the ongoing list of IEI, and new data on indications and outcomes have emerged. We review recent data and progress in the field of hematopoietic cell transplantation (HCT) for IEI including new diseases and complications.
View Article and Find Full Text PDFJ Cutan Pathol
November 2024
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
Ocul Immunol Inflamm
November 2024
Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Clin Case Rep
November 2024
Clinical Research Development Unit, Afzalipour Hospital Kerman University of Medical Sciences Kerman Iran.
World J Surg
November 2024
Department of General Surgery, Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
Background: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory, and benign breast disease. Its unclear etiology may involve autoimmune reactions, secretion-related factors, and microorganisms.
Aim: To analyze data from our IGM patient series and compare potential etiological factors.
J Allergy Clin Immunol
November 2024
Department of Medicine, DIMED, University of Padova, Padova, Italy; Internal Medicine 1, Ca' Foncello University Hospital, AULSS2, Treviso, Italy.
Background: Respiratory disease is a frequent cause of morbidity and mortality in common variable immunodeficiencies (CVIDs); however, lung function trajectories are poorly understood.
Objective: We sought to determine lung physiology measurements in CVIDs, their temporal trajectory, and their association with clinical and immunologic parameters.
Methods: This retrospective study from 5 Italian centers included patients with CVIDs who had longitudinal pulmonary function tests (PFTs) and chest computed tomography scan available.
Tunis Med
November 2024
Department of Internal Medicine, Rabta University Hospital Center, Tunisia.
Introduction: Sarcoidosis is a chronic inflammatory disease characterized by non-caseous necrotizing epithelial cell granulomas that can affect any organ. Ear, nose, and throat (ENT) involvement is rare. We report two cases of systemic sarcoidosis with ENT onset.
View Article and Find Full Text PDFMed Mycol Case Rep
December 2024
Université Paris Cité, Faculté de Médecine, APHP, Hôpital Necker Enfants malades, Service de Maladies Infectieuses et Tropicales, 149 rue de Sèvres, 75015, Paris, France.
is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
December 2024
Department of ENT, Sree Mookambika Medical College, Kulashekaram, Kanyakumari, India.
Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidium seeberi, typically involving nasal cavity and nasopharynx. They usually present with epistaxis, nasal obstruction, anosmia, and headache. In India, it is endemic in coastal areas of Orissa, Tamil Nadu, Kerala, Karnataka and Pondicherry states.
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