1 results match your criteria: "Chronic Disease Management Center of Hunan Provincial People's Hospital[Affiliation]"
Article Synopsis
- - Allergic rhinitis (AR) is caused by environmental allergens and involves inflammation of the nasal mucosa, with key focus on the IL-33/ST2 axis and ERK1/2 signaling pathways needing more research.
- - The study constructed an AR model using HNEpC cells treated with Der p1 and employed various techniques (qRT-PCR, Western blotting, ELISA, flow cytometry) to assess levels of inflammatory markers like IL-33, ST2, TNF-α, IL-6, and IL-8.
- - Results showed that levels of inflammatory markers increased significantly in the AR model but could be reversed by silencing IL-33 or ST2, indicating that IL-33