1,245 results match your criteria: "Christ Hospital[Affiliation]"

Article Synopsis
  • The Society for Cardiovascular Angiography & Interventions (SCAI) focuses on supporting interventional cardiology professionals and patients through various initiatives.
  • The SCAI Scientific Oversight Committee reviews the scientific needs of its members annually, utilizing survey-based research to understand practice patterns and perspectives.
  • This document serves as a guide for developing relevant surveys, ensures transparency in the survey process, establishes evaluation criteria, and encourages collaboration among SCAI members to enhance the impact of findings within the cardiology community.
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This consensus document for the performance of cardiovascular computed tomography (CCT) to guide intervention in the right ventricular outflow tract (RVOT) in patients with congenital disease (CHD) was developed collaboratively by pediatric and adult interventionalists, surgeons and cardiac imagers with expertise specific to this patient subset. The document summarizes definitions of RVOT dysfunction as assessed by multi-modality imaging techniques and reviews existing consensus statements and guideline documents pertaining to indications for intervention. In the context of this background information, recommendations for CCT scan acquisition and a standardized approach for reporting prior to surgical or transcatheter pulmonary valve replacement are proposed and presented.

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Left main coronary artery disease subtends a large area of potentially jeopardized myocardium. Percutaneous coronary intervention for severe left main coronary artery disease is a reasonable treatment option for select patients. Severe coronary artery calcium of the left main artery increases the complexity of percutaneous coronary intervention and is associated with increased risk of periprocedural complications and worse long-term clinical outcomes.

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Coronary Intravascular Lithotripsy for Treatment of Severely Calcified Lesions: Long-Term Sex-Specific Outcomes.

J Soc Cardiovasc Angiogr Interv

November 2023

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

Article Synopsis
  • Intravascular lithotripsy (IVL) is effective and safe for preparing calcified lesions before drug-eluting stent placement, particularly in women, compared to other treatment options which can lead to more complications.
  • A study analyzing data from 448 patients found that women were generally older, less likely to smoke, and had smaller and shorter lesions than men, yet resulted in similar angiographic outcomes and complication rates post-procedure.
  • Long-term results showed no significant differences in major adverse cardiac events or target lesion failure between women and men at 1 year, indicating that IVL has comparable safety and effectiveness across sexes.
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Background: Severe calcific aortic stenosis (AS) can be successfully treated with transcatheter aortic valve replacement (TAVR) using both balloon-expandable valves (BEV) and self-expanding valves. Challenges remain for treatment of AS with TAVR in relation to the severity of calcification involving valve leaflets, aortic annulus, and/or left ventricular outflow tract. Severe calcification presents challenges to TAVR with respect to aortic root/annular rupture and risk for peri-valve leak (PVL).

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Objectives: Assess temporal changes, intercenter variability, and birthing person (BP) factors relating to interventions for extremely early deliveries.

Methods: Retrospective study of BPs and newborns delivered from 22-24 completed weeks at 13 US centers from 2011-2020. Rates of neonatology consultation, antenatal corticosteroids, cesarean delivery, live birth, attempted resuscitation (AR), and survival were assessed by epoch, center, and gestational age.

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This case report discusses the functional outcomes and multidisciplinary coordination of care for a patient with hemiplegia due to stroke complicated by a migrated inferior vena cava (IVC) filter embedded in the right side of the heart. The patient suffered an acute right-sided stroke with hemorrhagic transformation requiring hemicraniectomy with left hemiplegia. The patient developed a subsequent pulmonary embolism requiring IVC filter placement as anticoagulation was contraindicated due to risk of further intracranial hemorrhage.

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Background: In patients with angina and non-obstructive coronary artery disease (ANOCA), diagnosis of coronary microvascular dysfunction (CMD) remains an unmet need. Magnetocardiography (MCG), is a rest-based, non-invasive scan that can detect weak electrophysiological changes that occur at the early phase of ischemia.

Objective: This study assessed the ability of MCG to detect CMD in ANOCA patients as compared to reference standard, invasive coronary flow reserve (CFR).

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Background: This study aimed to evaluate the impact of race on in-hospital outcomes of Takotsubo cardiomyopathy using the National Inpatient Sample.

Methods And Results: We conducted a retrospective study using data from the National Inpatient Sample database 2006 to 2018. We focused on Takotsubo cardiomyopathy hospitalizations, excluding those with acute coronary syndrome as the primary diagnosis.

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Continuum of Preshock to Classic Cardiogenic Shock in the Critical Care Cardiology Trials Network Registry.

JACC Heart Fail

September 2024

Levine Cardiac Intensive Care Unit, TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Article Synopsis
  • This study examines different patient phenotypes along the transition from preshock to cardiogenic shock (CS) to understand their prognostic implications and outcomes.* -
  • It classifies nearly 2,500 admissions into four categories and finds that in-hospital mortality rates vary significantly, from 3.6% for isolated low cardiac output to 24.0% for SCAI stage C CS.* -
  • Results indicate that patients in the earlier stages of shock can still experience a high risk of deteriorating, suggesting the need for improved definitions and severity assessments in CS.*
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Background: Implantable cardioverter-defibrillators are used globally and are reliable, but complications related to transvenous leads remain a concern. Evidence related to the incidence and costs of those complications is heterogeneous with respect to scope and healthcare system. This analysis aims to create estimates of the incidence and costs of tricuspid valve (TV) complications, lead failures, and lead extractions from a single large real-world data set.

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Introduction: In-Hospital Cardiac Arrest (IHCA) after ST-segment Elevation Myocardial Infarction (STEMI) is a subset of IHCA with high morbidity. While information on this selected group of patients is limited, closer inspection reveals that this is a challenging patient population with certain risk factors for IHCA following treatment of STEMI.

Areas Covered: In this review article, strategies for prevention of IHCA post STEMI are reviewed, as well as best-practices for the care of STEMI patients post-IHCA.

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The Role of Psychosocial Stress on Cardiovascular Disease in Women: JACC State-of-the-Art Review.

J Am Coll Cardiol

July 2024

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA. Electronic address:

Psychosocial stress can affect cardiovascular health through multiple pathways. Certain stressors, such as socioeconomic disadvantage, childhood adversity, intimate partner violence, and caregiving stress, are especially common among women. The consequences of stress begin at a young age and persist throughout the life course.

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Article Synopsis
  • A study was conducted to evaluate the impact of the adaptive pacing algorithm (aCRT) on clinical and economic outcomes for patients receiving cardiac resynchronization therapy (CRT).
  • Previous trials showed mixed results regarding the effectiveness of aCRT, highlighting the need for further real-world analysis.
  • The results indicated that patients using aCRT experienced lower mortality rates, fewer hospital readmissions, reduced healthcare visits, and lower healthcare costs compared to those on standard CRT.
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Papillary fibroelastomas (PFEs) are rare benign cardiac tumors typically arising from the valvular endocardium, often affecting the aortic and mitral valves. They can range from asymptomatic to causing severe thromboembolic complications like stroke. This article presents a case of a tricuspid valve PFE in an 81-year-old patient with severe multi-vessel coronary artery disease.

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Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries.

Heart Lung

October 2024

Division of Neuroscience Critical Care, Departments of Neurology, Neurosurgery, and Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Article Synopsis
  • A study was conducted to compare stroke incidences and mortality rates in critically ill COVID-19 patients from low-and middle-income countries (LMICs) and high-income countries (HICs).
  • The results showed that stroke incidence was significantly higher in LMICs (35.7 per 1000 admitted-days) compared to HICs (17.6 per 1000 admitted-days), with patients from LMICs also facing higher mortality rates (43.6% vs. 29.2%).
  • The findings highlight the need for better stroke diagnosis and healthcare resource allocation in LMICs, as both higher income status and the presence of stroke are associated with increased risk of death
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Lambl's excrescence is a rare valvular finding of uncertain pathologic significance. This case describes a previously healthy 42-year-old woman experiencing a sudden onset of word-finding difficulty. MRI of the brain demonstrated acute and chronic infarcts, prompting echocardiography, which revealed Lambl's excrescence of the aortic valve.

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Coronary arteriovenous fistulas (CAVFs) are congenital or acquired communications between the coronary arteries and coronary venous system, and they can also include other cardiac structures or vasculature. We discuss a case of a large fistula between the left main coronary artery and the right atrium in a geriatric patient with a history of gastrointestinal arteriovenous malformations (AVM). The occurrence of CAVFs, an uncommon cardiac irregularity, is particularly infrequent among older adults.

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Article Synopsis
  • Maternal mortality in the U.S. is a significant public health issue, with cardiovascular disease (CVD) being a leading cause of related deaths and health complications.
  • Labor and delivery pose heightened risks for pregnant individuals with CVD, yet there is varied approach to management due to a lack of high-quality randomized studies.
  • To address this, a panel of experts including cardiologists and obstetricians has come together to create practical guidelines for managing labor and delivery for high-risk patients with CVD, covering aspects like delivery method, timing, and use of medical devices.
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Article Synopsis
  • - The CLEAR SYNERGY trial is investigating the safety and effectiveness of low-dose colchicine and spironolactone in reducing major cardiovascular events in patients recovering from a heart attack (myocardial infarction).
  • - This large, randomized controlled study includes 7,062 participants from 104 centers across 14 countries and uses a factorial design to compare the treatments against placebos, focusing on specific cardiovascular outcomes.
  • - Results are expected to be presented in fall 2024, and the study aims to provide valuable data on these medications' impact on post-MI patients who have undergone a procedure called percutaneous coronary intervention.
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Article Synopsis
  • - The
  • REDUCE LAP-HF II
  • trial showed that the
  • Corvia Atrial Shunt
  • did not improve heart failure outcomes compared to a sham procedure, despite identifying "responders" who exhibited better exercise-related metrics after 12 months.
  • - This study aimed to assess the
  • long-term efficacy and safety
  • of the atrial shunt over 2 years, focusing on both overall patient outcomes and distinctions between responders and nonresponders.
  • - Results from
  • 621 patients
  • indicated no significant difference in major health events between the shunt and sham groups, but those with shunts experienced a higher rate of major adverse cardiac events and increased right ventricular volume; however, responders showed improved outcomes compared to the sham
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