[Research Progress of Tumor-associated Neutrophils in the Occurrence and Development of Lung Cancer].

Lung cancer is the malignant tumor with the highest mortality rate worldwide. The tumor microenvironment (TME) is a key factor in the progression of lung cancer, composed of tumor cells, signaling molecules, fibroblasts, immune cells, etc. Among them, tumor associated neutrophil (TAN), as an important component of immune cells in the TME, plays multiple roles in tumor cell proliferation, invasion, angiogenesis, and metastasis due to its aberrant function, and is closely associated with poor prognosis.

Integration of small needle knife in treating inflammatory factors, Th17 cell function, and magnetic resonance imaging evaluation in osteoporosis complicated by compression fractures in elderly patients.

Objective: The incidence of osteoporosis complicated by vertebral compression fractures (OVCF) has been increasing annually, and percutaneous vertebroplasty (PVP) is the main surgical approach for it. It was to evaluate the use of a small needle knife (SNF) in conjunction with PVP to assess changes in inflammatory response, Th17 cell function, and magnetic resonance imaging (MRI) parameters in OVCF patients.

Methods: A retrospective analysis was conducted using the clinical data of 138 patients with OVCF, who were categorized into PVP group (n = 65) and PVP + SNF group (n = 73).

Contradictory Mechanisms of rheumatoid arthritis and hepatitis B virus infection activation.

Rheumatoid arthritis (RA) is associated with a high rate of hepatitis B virus (HBV) infection. A large proportion of HBV reactivation may occur in RA patients after immunosuppression treatment, while fulminant hepatitis may occur in severe cases. Immunosuppressants are fundamental medications for the treatment of RA but carry the risk of inducing HBV reactivation.