1,553 results match your criteria: "Choanal Atresia"

This article reports a case of congenital choanal atresia with additional nostril and nasal deformities admitted to Henan Children's Hospital. A 43-day-old female patient was admitted to the hospital because of wheezing with mouth opening breathing and restricted feeding after birth'. The patient was diagnosis as bilateral congenital posterior nostril membranous atresia, congenital extra nostril nasal deformity and nasal stenosis by fiberoptic nasopharyngoscopy, CT, gene detection, and physical examination results.

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Desanto-Shinawi syndrome (DESSHS) is a rare autosomal dominant disorder caused by a loss of function variant or deletion of the WAC gene. DESSHS is characterized by dysmorphic features and global developmental delay. In this report, we discuss three boys with DESSHS.

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Bilateral Choanal Atresia in 24 Years Old Woman: A Case Report.

Indian J Otolaryngol Head Neck Surg

October 2024

Department of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Assiut, 71511 Egypt.

Article Synopsis
  • Choanal atresia is a congenital condition where the nasal passages don't properly form, leading to breathing difficulties, and can often go unnoticed, especially if it's unilateral.
  • A 24-year-old woman experienced chronic nasal obstruction and underwent endoscopic surgery to correct bilateral choanal atresia, successfully restoring airflow.
  • Early surgical treatment is crucial for infants, but adult cases are rare; diagnostic tools like nasal endoscopy and CT scans are essential for planning the surgery.
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Chromosomal rearrangement can disrupt gene function by interfering with coding sequences or their regulatory regions. The breakpoint in these rearrangements can pinpoint the disease-related gene's location. This paper presents two rare cases of chromosomal rearrangement involving chromosome 6 (6p24-25) and chromosome 14 (14q22-23).

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Congenital nasal pyriform aperture stenosis (CNPAS) is a rare but potentially life-threatening cause of upper airway obstruction in infants. It was first described in 1988 and 1989 in the radiology and otolaryngology literature. Congenital airway obstruction affects up to 1 in 5,000 infants, and many of these obstructions result from choanal atresia.

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Congenital nasal pyriform aperture stenosis is a newly defined clinical entity that causes nasal airway obstruction in neonates due to the narrowing of the pyriform aperture, which is the narrowest and most anterior portion of the nasal airway. As newborns are obligate nasal breathers except when crying, a child with bilateral nasal pyriform aperture obstruction presents as an acute airway emergency, resulting in apnea and cyanosis. This entity should be kept in the differential diagnosis of any neonate or infant presenting with signs and symptoms of upper airway obstruction.

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To investigate the application of low temperature plasma ablation combined with fullly degradable sinus stent system in the treatment of congenital choanal atresia mainly menbranous atresia. A child with membranous bilateral choanal atresia admitted in April 2023 was analyzed. This case underwent endoscopic ablative posterior nostriplasty and placed a fully degradable drug stent in bilateral operative cavities.

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Choanal atresia: a review of contemporary treatment strategies.

Curr Opin Otolaryngol Head Neck Surg

December 2024

Department of Pediatric Otolaryngology-Head and Neck Surgery, CHRISTUS Children's Hospital, Baylor College of Medicine, San Antonio, Texas, USA.

Article Synopsis
  • Choanal atresia (CA) is a serious congenital issue that may need immediate surgery, with endoscopic techniques becoming the standard approach, although up to 50% of cases can experience restenosis requiring further surgery.
  • Recent advancements include the use of bioabsorbable, steroid-eluting stents that have been adapted for CA since 2017, showing promising results without complications or restenosis.
  • Ongoing research on these stents raises hope for better surgical outcomes in CA repairs, but more studies are needed to confirm their safety and effectiveness.
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[Choanal atresia in an alpaca cria (Vicugna pacos)].

Tierarztl Prax Ausg G Grosstiere Nutztiere

June 2024

Klinik für kleine Klauentiere und forensische Medizin und Ambulatorische Klinik, Stiftung Tierärztliche Hochschule Hannover.

Article Synopsis
  • An alpaca baby (called a cria) was very weak and had trouble breathing after it was born, especially when trying to drink milk.
  • The vets found that it had choanal atresia, a condition where a part of its nose is not formed properly, and sadly had to put the cria to sleep.
  • This report helps people learn more about choanal atresia so that they can recognize it early in other baby alpacas.
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Choanal atresia is an uncommon condition with an incidence of 1:5,000-8,000 live births, affecting females more frequently and often associated with other malformations. This case report presents a 42-year-old female patient who was born with bilateral choanal atresia and intervened surgically for the first time at birth. However, the formed orifice was reobstructed a few months afterward, necessitating reoperation in adulthood.

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Neonatal Nasal Obstruction: A Comprehensive Analysis of Our 20 Years' Experience.

Indian J Otolaryngol Head Neck Surg

June 2024

Department of Otorhinolaryngology and Head & Neck Surgery, Children's Airway& Swallowing Center, Manipal Hospital, Bangalore, Karnataka India.

Neonates are obligatory nasal breathers hence nasal obstruction is a very important symptom to be evaluated. Although causes can be trivial most of the time, they can be life-threatening in some. Respiratory distress immediately after birth, feeding difficulties, paradoxical cyanosis, and failure to thrive are the most evident symptoms, and determination of unilateral or bilateral involvement guides the rationale for elective or emergency intervention.

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Bosma arhinia microphthalmia syndrome (BAMS, OMIM #603457) is a rare autosomal dominant disorder caused by heterozygous variation in the SMCHD1 gene on chromosome 18p11. Clinically, it is characterized by microphthalmia, absence or hypoplasia of nose, choanal atresia, anosmia, palatal abnormalities, hypogonadotropic hypogonadism, and cryptorchidism. Here we report a Brazilian patient with a likely pathogenic variation in SMCHD1 gene (c.

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Unlabelled: The article presents literature and our own data on surgical treatment and options for solving the problem of restenosis for congenital choanal atresia in children under one year of age. A new stentless choanoplasty technique using fibrin glue for fixation of posterior septal flaps is presented. This method has patent No.

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Disorder-Not CHARGE Syndrome-Presenting as Isolated Cochleovestibular Dysfunction.

Genes (Basel)

May 2024

Department of Head and Skin, Faculty of Medicine and Health Sciences, Ghent University Hospital, 9000 Ghent, Belgium.

CHARGE syndrome, characterized by a distinct set of clinical features, has been linked primarily to mutations in the gene. Initially defined by specific clinical criteria, including coloboma, heart defects, choanal atresia, delayed growth, and ear anomalies, CHARGE syndrome's diagnostic spectrum has broadened since the identification of . Variants in this gene exhibit considerable phenotypic variability, leading to the adoption of the term " disorder" to encompass a wider range of associated symptoms.

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Background: Bosma arhinia microphthalmia syndrome (BAMS; MIM603457) is a rare genetic disorder, predominantly autosomal dominant. It is a multi-system developmental disorder characterized by severe hypoplasia of the nose and eyes, and reproductive system defects. BAMS is extremely rare in the world and no cases have been reported in Chinese population so far.

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Clinical and computed tomography findings in cats with nasopharyngeal stenosis.

J Small Anim Pract

September 2024

Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.

Objectives: Concurrent anomalies are often found in nasopharyngeal stenosis and choanal atresia; some seem to be of primary nature, whereas others may be coincidental. This study aimed to report the computed tomography features and related comorbidities of these diseases.

Materials And Methods: A cross-sectional retrospective study was performed using case and control groups defined according to the presence of signs of upper airway disease and the presence/absence of nasopharyngeal stenosis, respectively.

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Article Synopsis
  • Bilateral congenital choanal atresia (CCA) requires timely intervention for safe breathing, but sometimes surgery is delayed until the infant is better able to handle it.
  • In a reported case, an infant could breathe orally without issue but developed thickening of the closure wall during the wait for elective surgery, which was eventually performed when the child was 10 weeks old.
  • The outcomes showed successful nasal breathing post-surgery, highlighting the need to carefully balance the timing of intervention against the risk of worsening the condition while waiting.
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Unilateral Choanal Atresia in a Child With Prolonged Nasal Congestion.

Cureus

April 2024

Biostatistics, Epidemiology, and Public Health, Graduate Medical Education, Kansas City University, Kansas City, USA.

Choanal atresia obstructs the nasal passage due to abnormal bony or soft tissue remnants owing to the faulty canalization of the nasal passages during fetal development. The clinical manifestations are more pronounced in bilateral cases, often presenting immediately after birth with cyanosis turning pink when crying, as newborns are obligatory nasal breathers. This contrasts in unilateral cases, where the condition may present with mild symptoms and be diagnosed later in life.

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Article Synopsis
  • The review discusses current research and discussions in pediatric rhinology, focusing on the collaboration between otorhinolaryngologists and pediatricians.
  • It covers congenital malformations like choanal atresia and nasal dermoid cysts, along with treatments for sinogenic orbital complications and chronic rhinosinusitis in children.
  • Additionally, it updates on the ENT specialist's role in managing children with cystic fibrosis and primary ciliary dyskinesia.
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Here we report the case of a young boy with developmental delay, thin sparse hair, early closure of the anterior fontanel, bilateral choanal atresia, brachyturicephaly; and dysmorphic features closely resembling those seen in trichorhinophalangeal syndrome (TRPS). These features include sparse hair, sparse lateral eyebrows, a bulbous pear shaped nose, a long philtrum, thin lips, small/hypoplastic nails, pes planovalgus; bilateral cone-shaped epiphyses at the proximal 5th phalanx, slender long bones, coxa valga, mild scoliosis, and delayed bone age. Given that TRPS had been excluded by a thorough genetic analysis, whole exome sequencing was performed and a heterozygous likely pathogenic variant was identified in the FBXO11 gene (NM_001190274.

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The work illustrates a step-by-step surgical approach to demonstrate technical feasibility of a single-stage endoscopic repair for bilateral choanal atresia with adjuvant bioabsorbable steroid-eluting stent placement to safely mitigate unique perioperative challenges in the pediatric population. Laryngoscope, 134:4414-4417, 2024.

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Article Synopsis
  • Bosma syndrome (BAMS) is a rare condition identified in 1972, associated with unique physical features and diagnosed through specific criteria.
  • Research has indicated that mutations in the SMCHD1 gene may contribute to the syndrome's development, but not all patients exhibit the same genetic changes or symptoms.
  • The article discusses a new case with a different SMCHD1 variant and aims to enhance the understanding and diagnosis of Bosma syndrome by reviewing recent literature.
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Bosma arhinia microphthalmia syndrome (BAMS) is a rare syndrome consisting of several craniofacial abnormalities, including congenital arhinia. In this case report, the authors present the first case of a patient with BAMS and dacryocystocele who successfully underwent dacryocystectomy. Dacryocystectomy may serve as a viable surgical approach for dacryocystocele in patients with abnormal nasal anatomy.

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Article Synopsis
  • Crouzon syndrome with acanthosis nigricans (CAN) results from a specific genetic mutation and is characterized by craniosynostosis, midface hypoplasia, and hyperkeratotic skin disorders.
  • A study reviewed six patients diagnosed with CAN over 36 years, examining their medical histories and challenges related to speech, language, hearing, and feeding.
  • Findings indicated that all patients experienced significant complications such as airway management needs, feeding difficulties, and hearing loss, with common issues including low weight and communication disorders.
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