482 results match your criteria: "Cho Ray hospital[Affiliation]"

Article Synopsis
  • Cardiovascular electronic devices can identify atrial high-rate episodes (AHREs), but the specific predictors of significant AHREs were not well understood until this study.
  • In a study of 145 patients, around 30.3% experienced AHREs over a six-month period, with data collected on risk factors using Cox regression analysis.
  • Key risk factors linked to the development of AHREs included prior use of anti-arrhythmic drugs, history of paroxysmal supraventricular tachycardia, percentage of premature atrial contractions recorded on ECG, and left ventricular global longitudinal strain measurements.
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A case report involving incessant multi-types of supraventricular tachycardia and acute decompensated heart failure required a rescuing electrophysiology study and ablation. Ventricular fibrillation occurred due to coronary spasm, complicating the deteriorating heart. However, aggressive therapies, including extracorporeal support and the timely elimination of the culprit accessory pathway, successfully resolved the patient's condition.

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Helicobacter pylori disturbs the stomach lining during long-term colonization of its human host, with sequelae including ulcers and gastric cancer. Numerous H. pylori virulence factors have been identified, showing extensive geographic variation.

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  • Functional dyspepsia (FD) is a widespread issue that requires ruling out physical causes for diagnosis, but this can be tough in areas with limited resources.
  • A consensus was formed by 32 experts from Vietnamese universities to update guidelines for managing FD, using the Delphi method for structured discussions.
  • After two voting rounds, the panel approved 14 statements focusing on diagnostic tests and treatments for FD, aiming to aid physicians in effective management and share valuable data for the Asian region.
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  • Using a diluted 0.3% SDS solution for decellularizing small-diameter vascular bypass substitutes preserves the structural integrity of pig arteries better than the commonly used 0.5% SDS solution.
  • The study involves the use of physical methods like freezing and thawing, and takes measures to evaluate cell removal effectiveness and the safety of the resulting acellular tissues.
  • Results showed minimal residual DNA and no significant changes in mechanical properties, with the decellularized samples promoting cell growth, making them suitable for use in clinical blood vessel transplantation.
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Background Chemotherapy is a crucial component of multimodality treatment for lung cancer patients. Although considered a vital and effective approach, chemotherapy can induce adverse effects, negatively impacting patients' quality of life. These adverse effects can also lead to psychological issues, particularly depression and anxiety.

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Article Synopsis
  • - Familial hypercholesterolemia (FH) is a genetic disorder that causes high levels of low-density lipoprotein cholesterol (LDL-C) from a young age, increasing the risk for early cardiovascular diseases due to mutations in key cholesterol-related genes.
  • - A 44-year-old Vietnamese woman experienced chest pain and was diagnosed with acute myocardial infarction (AMI), leading to the identification of FH through clinical signs, elevated LDL-C levels, and a Dutch Lipid Clinic Network (DLCN) score of 10.
  • - The patient underwent a successful reverse T-stenting procedure for her coronary arteries and had a genetic test confirming a mutation in the LDL-R gene, reinforcing the diagnosis of FH; she has since
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eHealth Interventions of Health Literacy for Stroke Survivors: Systematic Review and Meta-Analysis.

Public Health Nurs

September 2024

International Ph.D. Program in Gerontology and Long-Term Care, College of Nursing, Taipei Medical University, Taipei City, Taiwan.

Background: eHealth literacy interventions have emerged as a new approach in management of stroke survivors. Its effect on knowledge and clinical outcomes presents an inconsistent result in literature.

Objectives: We aim to evaluate the impact of eHealth interventions on health literacy, clinical metrics, adherence to healthy behaviors, stroke recurrence, mortality, and health-related quality of life in stroke survivors.

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Article Synopsis
  • - Familial hypercholesterolemia (FH) is a genetic disorder leading to high LDL cholesterol levels and is a significant cause of early coronary artery disease, especially in developing countries.
  • - A study in Vietnam aimed to determine the prevalence of genetically defined FH among 218 patients with premature acute myocardial infarction (AMI), finding a 14.7% rate of potential FH diagnoses.
  • - The study revealed that patients with FH had much higher LDL levels and more severe heart disease compared to those without FH, highlighting the need for better screening and management of this condition to mitigate cardiovascular risks.
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  • - The study analyzes the oncologic outcomes for patients with biochemical recurrence (BCR) after radical prostatectomy (RP) who underwent either lymph node dissection (LND) or radiation therapy (RT) for positive lymph node recurrences detected by PET scans.
  • - It reviewed data from 2476 patients across 19 studies, finding that LND had higher rates of PSA and systemic progressions compared to RT, despite overall low mortality rates for both treatments.
  • - The authors emphasize the need for clearer trial designs in future research, particularly regarding the timing of PSMA PET scans and the use of concurrent systemic therapies alongside salvage treatments.
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Early recognition of severe acute pancreatitis (AP) is crucial for timely intervention. This study aims to evaluate the prognostic accuracy of the Emergency Room Assessment of AP (ERAP) score and compare it with the Bedside Index for Severity in AP (BISAP) score in predicting severe AP, mortality, and persistent multiple organ failure (MOF) in Vietnamese patients. This prospective cohort study included AP patients admitted to Cho Ray Hospital between August 2021 and May 2022.

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Chronic obstructive pulmonary disease (COPD) stands as one of the leading causes of mortality worldwide. Acute exacerbations of COPD (AECOPD) lead to rapid respiratory function decline and worsened disease status. Despite recent studies, the ability of the neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in patients with COPD remains controversial.

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Background: Heart failure is one of the leading causes of mortality and hospitalization in cardiovascular patients. Guideline-directed medical treatment (GDMT) in the current era includes novel medications such as ARNI and SGLT2 inhibitors, as well as an approach to treatment based on clinical phenotypes. To assess prognostic factors for mortality and hospital readmissions plays a crucial role in patient care.

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Obturator hernia, an uncommon type of abdominal wall hernia, predominantly occurs in elderly, multiparous women and often presents with nonspecific symptoms. The preoperative diagnosis of obturator hernia is particularly challenging due to its vague clinical manifestations. The clinical picture consists of intestinal blockage, abdominal pain, nausea, and vomiting.

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Eosinophilic gastroenteritis poses a significant diagnostic challenge, particularly in developing countries, where the awareness of this condition may be limited. Here, the case of a patient in her early 30s, who presented with recurrent episodes of abdominal pain and diarrhea, is reported. Initial standard laboratory investigations revealed normal complete blood counts and elevated total serum immunoglobulin E levels.

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Desmoid fibromatosis (DFs) is rare, low-grade neoplasm. Although it poses no risk of metastasis, DFs exhibits a range of clinical manifestations characterized by local infiltrative growth tendencies and a propensity for recurrence. Despite its nonmalignant nature, DFs can be highly debilitating and occasionally life-threatening, causing severe pain and functional limitations.

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Bleeding complications are frequently observed in patients undergoing extracorporeal membrane oxygenation and are associated with increased mortality. Due to the complex mechanisms, managing bleeding during ECMO remains a challenge. Acquired von Willebrand syndrome (AVWS) in ECMO highlights a potentially reduced affinity of von Willebrand factor (vWF) for binding to platelets and collagen in response to vascular damage, thus contributing to increased bleeding in ECMO patients.

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Article Synopsis
  • Prophages significantly influence the characteristics of pathogenic bacteria, yet their ecological and evolutionary roles, particularly in bacteria linked to gastric cancer, are not well understood.
  • A comprehensive analysis of 1,011 complete clinical genomes revealed that 29.5% contain prophages, with only 32.2% being complete, and their distribution varies by geography and ancestry but not by the disease status of hosts.
  • The study uncovered mechanisms of prophage inactivation and proposed a new model for regulating the lysogenic-lytic cycle, providing a deeper understanding of how prophages impact bacterial genetics and adaptation.
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Background: Patients with EGFR-mutated non-small-cell lung cancer (NSCLC) and MET amplification as a mechanism of resistance to first-line osimertinib have few treatment options. Here, we report the primary analysis of the phase 2 INSIGHT 2 study evaluating tepotinib, a highly selective MET inhibitor, combined with osimertinib in this population.

Methods: This open-label, phase 2 study was conducted at 179 academic centres and community clinics in 17 countries.

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Thrombotic complications during and after extracorporeal membrane oxygenation (ECMO) are commonly observed clinically. The incidences of cannula-associated deep vein thrombosis (CaDVT) post-ECMO support have predominantly focused on Caucasian demographics. This study aims to determine the incidence and risk factors for CaDVT in Vietnamese patients following ECMO decannulation.

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Machine Learning Approaches for Stroke Risk Prediction: Findings from the Suita Study.

J Cardiovasc Dev Dis

July 2024

Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, 3-17 Senrioka-Shinmachi, Settsu 566-0002, Japan.

Stroke constitutes a significant public health concern due to its impact on mortality and morbidity. This study investigates the utility of machine learning algorithms in predicting stroke and identifying key risk factors using data from the Suita study, comprising 7389 participants and 53 variables. Initially, unsupervised k-prototype clustering categorized participants into risk clusters, while five supervised models including Logistic Regression (LR), Random Forest (RF), Support Vector Machine (SVM), Extreme Gradient Boosting (XGBoost), and Light Gradient Boosted Machine (LightGBM) were employed to predict stroke outcomes.

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Introduction: The Charlson Comorbidity Index ≥2, in-Hospital onset, Albumin <2.5 g/dL, altered Mental status, Eastern Cooperative Oncology Group Performance status ≥2, Steroid use (CHAMPS) score is a novel and promising prognostic tool. We present an initial external validation of the CHAMPS score for predicting mortality in acute nonvariceal upper gastrointestinal bleeding (NVUGIB) across multiple clinical outcomes.

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Introduction: Patients experiencing an out-of-hospital cardiac arrest (OHCA) frequently do not receive bystander cardiopulmonary resuscitation (CPR), especially in low- and middle-income countries (LMIC). In this study we sought to determine the prevalence of OHCA patients in Vietnam who received bystander CPR and its effects on survival outcomes.

Methods: We performed a multicenter, retrospective observational study of patients (≥18 years) presenting with OHCA at three major hospitals in an LMIC from February 2014-December 2018.

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Impact of proximity of left atrium to descending aorta on left inferior pulmonary vein triggers or drivers of atrial fibrillation: A risk score model.

Heart Rhythm

January 2025

Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine and Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan; National Chung Hsing University, Taichung, Taiwan.

Article Synopsis
  • - The study investigated the relationship between the distance from the descending aorta to the left inferior pulmonary vein (Dao-LIPV) and the presence of triggers and drivers in atrial fibrillation (AF) during ablation procedures.
  • - A total of 886 patients with drug-refractory AF were analyzed; 63 were found to have LIPV triggers or drivers, with Dao-LIPV distance proving to be a strong predictor for these occurrences.
  • - The research developed a risk score model indicating that patients with a Dao-LIPV distance of 2.5 mm or less and persistent AF have a significantly higher risk of LIPV triggers or drivers, which can help electrophysiologists plan ablation treatments more effectively.*
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Article Synopsis
  • * A systematic review of 141 studies identified 33 relevant studies that included 79 AFE patients, mostly occurring during cesarean sections, with a median maternal age of 34 years and a gestational age of 37.5 weeks.
  • * The review found a maternal survival rate of 72% with ECMO treatment, noting that while most patients fared well, there were some neurological issues; early initiation of ECMO is recommended,
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