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Background And Objectives: Invasive pulmonary aspergillosis (IPA) among patients with chronic obstructive pulmonary disease (COPD) is increasing in frequency. We conducted this study to find out the approximate incidence of IPA in patients with acute exacerbation of COPD (AECOPD), and to determine whether using a combination of two tests (galactomannan [GM] antigen and 1,3-beta-glucan [BG] detection) would result in a more specific diagnosis of IPA.

Methods: The study included 261 patients with AECOPD admitted over two years.

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