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[Effects of musk glucoprotein on chemotaxis of polymorphonuclear leukocytes in vivo and in vitro].

Zhongguo Zhong Yao Za Zhi

January 2003

Institute of Materia Medica, Chinese Academy of Medical Sciences, Chinese Peiking Union Medical College, Beijing 100050.

Objective: To investigate the effects of Musk glucoprotein on chemotaxis of Polymorphonuclear leukocytes(PMN).

Method: The chemotaxis of PMN in abdominal cavity in rat induced by carboxymethyl cellulose(CMC) was used as an in vivo animal model and in in vitro it was evaluated by Boyden chamber. The concentration of cytosolic free Ca2+ was quantitated with the fluorescent Ca2+ indicator Fura-2.

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