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Chinese PLA Genearal Hospital[Affiliation] Publications | LitMetric

2 results match your criteria: "Chinese PLA Genearal Hospital[Affiliation]"

[HOXA9 is direct target of miR-196a].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi

February 2011

Department of Hematology, Chinese PLA Genearal Hospital, Beijing 100853, China.

Aim: To analyze the possible epigenetic regulation mechanism of HOXA9 gene expression and find the possible microRNA regulating HOXA9 gene expression.

Methods: Targetscan software was used to analyze potential microRNA target sites in 3'-UTR of human HOXA9. 3'-UTR fragment of HOXA9 was amplified by PCR.

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[Targeted regulation of mll-af4 fusion gene by miR-142-3p].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

December 2010

Department of Hematology, Chinese PLA Genearal Hospital, Beijing 100853, China.

In order to analyze the possible epigenetic regulation mechanism of mll-af4 gene expression and find the possible microRNA regulating mll-af4 gene expression, targetscan software was used to analyze potential microRNA target sites in 3'-UTR of mll-af4. 3'-UTR fragment of mll-af4 was amplified by PCR. PCR products were cloned into EcoR I/Pst I-digested pGL3-M reporter vector, placing the 3'-UTR with potential microRNA binding site downstream of coding sequence of luciferase.

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