1 results match your criteria: "Chinese Center for Disease Control and PreventionBeijing 100088[Affiliation]"
IER5 promotes irradiation- and cisplatin-induced apoptosis in human hepatocellular carcinoma cells.
Am J Transl Res
May 2016
National Institute for Radiological Protection, Chinese Center for Disease Control and PreventionBeijing 100088, China; Key Laboratory of Radiological Protection and Nuclear Emergency, Chinese Center for Disease Control and PreventionBeijing 100088, China.
Purpose: To elucidate the mechanisms of the immediate-early response gene 5 (IER5) effect on the apoptosis induced by irradiation and cisplatin (CDDP) in human hepatocellular carcinoma (HepG2) cells.
Methods: We generated IER5 overexpression stable cells (HepG2/IER5) using Lipofectamine 2000 transfection HepG2 cells. Cell apoptosis was induced by irradiation and cisplatin treatments, and cell proliferation (viability) and apoptosis were evaluated by MTT and flow cytometry assays.