1 results match your criteria: "ChinaJapan Friendship Hospital[Affiliation]"
[Clinicopathological and genetic analysis of interstitial disease-like pulmonary intravascular large B cell lymphoma].
Zhonghua Xue Ye Xue Za Zhi
September 2024
Department of Pathology, ChinaJapan Friendship Hospital, Beijing 100029, China.
Article Synopsis
- - The study analyzed the clinicopathological features and genetic mutations of pulmonary intravascular large B cell lymphoma in eight patients between April 2018 and May 2023, revealing a median age of 64 and a predominance of respiratory symptoms.
- - High-resolution chest CT scans showed diffuse ground-glass opacities in the lungs, with pulmonary function tests indicating varying degrees of dysfunction; most patients had elevated serum markers indicating advanced disease.
- - Genetic testing identified MYD88 and PIM1 as the most frequently mutated genes, while tumor cells exhibited characteristics typical of large B cell lymphoma and were found infiltrating blood vessels throughout the lung tissue.