3 results match your criteria: "China. wu.xu@zs-hospital.sh.cn.[Affiliation]"
Effects and long-term outcomes of endurance versus resistance training as an adjunct to standard medication in patients with stable COPD: a multicenter randomized trial.
BMC Pulm Med
April 2024
Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, 180 Feng Lin Rd, Shanghai, 200032, China.
Article Synopsis
- The study aimed to evaluate the effectiveness of adding endurance training (ET) and resistance training (RT) to standard medical treatment for patients with chronic obstructive pulmonary disease (COPD), while also assessing improvements based on varying disease severities.
- It involved a multicenter, randomized clinical trial with 366 patients divided into three groups: standard medical treatment only, medical treatment plus ET, and medical treatment plus RT, with all participants undergoing exercise three times a week for 12 weeks.
- Results showed no significant differences in health-related quality of life and exercise capacity among the different training groups both immediately after the intervention and during the follow-ups, although a minor benefit was observed in traditional medical treatment.
CircESRP1 inhibits clear cell renal cell carcinoma progression through the CTCF-mediated positive feedback loop.
Cell Death Dis
November 2021
Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, No. 301, Yanchang Rd., Shanghai, 200072, China.
Circular RNA (circRNA), a closed continuous loop formed by back-splicing, has been confirmed to be implicated in a variety of human diseases including cancers. However, the underlying molecular mechanism of circRNA regulating the progression of renal cell carcinoma (RCC) remains largely unclear. In the present study, we identified a novel circular RNA, circESRP1, that derived from the ESRP1 gene locus at 8q22.
View Article and Find Full Text PDFHypoxic TAM-derived exosomal miR-155-5p promotes RCC progression through HuR-dependent IGF1R/AKT/PI3K pathway.
Cell Death Discov
June 2021
Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Hypoxic tumor-associated macrophages (TAMs) are related to poor prognosis of patients with clear cell renal cell carcinoma (ccRCC). Exosomes are small lipid-bilayer vesicles that implicated in tumor progression and metastasis. However, whether hypoxic TAM-derived exosomes affect RCC progression within the hypoxic tumor microenvironment has not been elucidated.
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