1 results match your criteria: "China. wanjun@301hospital.com.cn[Affiliation]"
Detection of K-ras gene mutation in fecal samples from elderly large intestinal cancer patients and its diagnostic significance.
World J Gastroenterol
March 2004
Department of Geriatric Gastroenterology, South Building of General Hospital of the Chinese PLA, Beijing, China.
Aim: To study the diagnostic significance of K-ras gene mutations in fecal samples from elderly patients with large intestinal cancer.
Methods: DNA was extracted in the fecal and tissue samples from 23 large intestinal cancer patients, 20 colonic adenomatoid polypus patients and 20 healthy subjects. The K-ras gene mutations at the first and second bases of codon 12 were detected by the allele specific mismatch method.