3 results match your criteria: "China. szbloodcenter@hotmail.com.[Affiliation]"
Small RNA sequencing data of plasma extracellular vesicles in a breast cancer screening population.
Sci Data
December 2024
Shenzhen Center for Chronic Disease Control, Shenzhen, 518020, P. R. China.
The pathogenesis of breast cancer is still unclear. Small RNAs associated with extracellular vesicles (EVs) have been found to be involved in tumor development. It is important to explore the role of EVs small RNAs in breast cancer.
View Article and Find Full Text PDFA machine learning model revealed that exosome small RNAs may participate in the development of breast cancer through the chemokine signaling pathway.
BMC Cancer
November 2024
Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410078, P. R. China.
Article Synopsis
- Exosome small RNAs may play a role in breast cancer pathogenesis, but their specific impact is not fully understood; this study aimed to identify key exosome small RNAs linked to breast cancer using machine learning.
- Peripheral blood samples from individuals with and without breast cancer were sequenced to compare small RNA expression levels, leading to the identification of six significant small RNAs that showed promise as biomarkers for the disease.
- The study found that these six small RNAs exhibit strong prognostic value, with their functions primarily highlighting involvement in the chemokine signaling pathway, warranting further investigation into their implications for early breast cancer detection.
Single-cell transcriptomic profiling reveals immune cell heterogeneity in acute myeloid leukaemia peripheral blood mononuclear cells after chemotherapy.
Cell Oncol (Dordr)
February 2024
Shenzhen Center for Chronic Disease Control and Prevention, Shenzhen Institute of Dermatology, Shenzhen, China.
Purpose: Acute myeloid leukaemia (AML) is a heterogeneous disease characterised by the rapid clonal expansion of abnormally differentiated myeloid progenitor cells residing in a complex microenvironment. However, the immune cell types, status, and genome profile of the peripheral blood mononuclear cell (PBMC) microenvironment in AML patients after chemotherapy are poorly understood. In order to explore the immune microenvironment of AML patients after chemotherapy, we conducted this study for providing insights into precision medicine and immunotherapy of AML.
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