5 results match your criteria: "China. li.xiaomu@zs-hospital.sh.cn.[Affiliation]"

Background: Chronic kidney disease (CKD) is prevalent among elderly patients with type 2 diabetes mellitus (T2DM). The association between dietary patterns and CKD in elderly T2DM patients remains understudied. This study aimed to investigate the relationship between dietary patterns and CKD in elderly Chinese patients with T2DM.

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Impact of cortisol on liver fat and metabolic health in adrenal incidentalomas and Cushing's syndrome.

Endocrine

September 2024

Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.

Article Synopsis
  • - This study analyzed liver fat content in patients with non-functional adrenal incidentalomas (NFAI), mild autonomous cortisol secretion (MACS), and Cushing's syndrome (CS), using CT scans and metabolic indicators to uncover potential connections with cortisol levels.
  • - Results showed that patients with MACS had a higher prevalence of non-alcoholic fatty liver disease (NAFLD) compared to those with NFAI, and both MACS and CS showed significant associations with NAFLD, indicating increased liver fat and metabolic issues.
  • - The findings also revealed that metabolic traits like HbA1c and the Triglyceride-glucose index significantly mediated the relationship between cortisol levels and liver fat, highlighting the intricate links between adrenal function and
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Thyroid function spectrum in Cushing's syndrome.

BMC Endocr Disord

June 2024

Department of Endocrinology, Zhongshan Hospital, Shanghai Medical College of Fudan University, Fenglin Road 180, Xuhui District, Shanghai, 200032, China.

Purpose: Thyroid disorders have been reported in hypercortisolism patients. Endogenous Cushing's syndrome (CS) potentially complicates its metabolic sequelae. We investigated thyroid function in CS patients to determine this relationship.

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Isolated adrenocorticotropic hormone deficiency following immune checkpoint inhibitors treatment often occurs in polyglandular endocrinopathies.

BMC Endocr Disord

July 2023

Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, No.180 Fenglin Road, Shanghai, 200032, China.

Background: With the increasing application of immune checkpoint inhibitors (ICI) in cancer therapy, the occurrence of isolated adrenocorticotropic hormone deficiency (IAD), as an adverse effect, is also on the rise. Nevertheless, there are only a few studies regarding IAD induced by ICI. This study aimed at investigating the characteristics of IAD induced by ICI and its relationship with other endocrine adverse events.

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Thyroid function and non-alcoholic fatty liver disease in hyperthyroidism patients.

BMC Endocr Disord

February 2021

Present address: The Department of Endocrinology, Zhongshan hospital, Fudan University, NO. 180 Fenglin Road, Shanghai, 200032, China.

Background: Although thyroid function has been demonstrated to be associated with non-alcoholic fatty liver disease (NAFLD) in different population, the prevalence and features of NAFLD in hyperthyroidism have not been reported. The present study aims to investigate the prevalence of NAFLD and association of thyroid function and NAFLD in hyperthyroidism patients.

Methods: This cross-sectional study was performed in Zhongshan Hospital, Fudan University, China.

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