1 results match your criteria: "China. dushiming@taihehospital.com.[Affiliation]"
Saikogenin A improves ethanol-induced liver injury by targeting SIRT1 to modulate lipid metabolism.
Commun Biol
November 2024
Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Department of neurosurgery, Taihe Hospital, School of Pharmaceutical Sciences, Hubei University of Medicine, Shiyan, China.
Article Synopsis
- * Saikosaponin A (SSa), a compound from Radix Bupleuri, shows potential in protecting the liver due to its anti-inflammatory and antioxidant effects, but its impact on ALD is not well-explored.
- * Research indicates that SSa and its metabolite Saikogenin A (SGA) work through specific liver signaling pathways and can protect liver cells from ethanol damage, positioning SGA as a promising candidate for ALD therapy.