2 results match your criteria: "China. Electronic address: qingrong-xia@ahmhcentre.com.[Affiliation]"

Evaluation of plasma-derived extracellular vesicles miRNAs and their connection with hippocampal mRNAs in alcohol use disorder.

Life Sci

August 2024

Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei 230001, China; The Grade 3 Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230001, China. Electronic address:

Article Synopsis
  • * This study investigated potential biomarkers by analyzing the expression of specific miRNAs in the plasma of AUD patients compared to healthy controls and used machine learning to identify those most relevant to AUD.
  • * The research identified 22 key miRNAs and established a network connecting these miRNAs to target genes in the hippocampus, offering insights that could improve the diagnosis and treatment of AUD moving forward.
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Comprehensive bioinformatics analysis and molecular validation of lncRNAs-mediated ceRNAs network in schizophrenia.

Life Sci

January 2023

Department of Pharmacy, Affiliated Psychological Hospital of Anhui Medical University, Hefei, Anhui 230000, China; Department of Pharmacy, Anhui Mental Health Center, Hefei, Anhui 230000, China; Department of Pharmacy, Hefei Fourth People's Hospital, Hefei, Anhui 230000, China. Electronic address:

Aims: The present study aimed to investigate how Schizophrenia (SCZ)-specific long non-coding RNAs (lncRNAs) served as competing endogenous RNAs (ceRNAs) to modulate the biological functions and pathways involved in the pathogenesis of SCZ.

Main Methods: Microarray dataset (GSE54913) was obtained from Gene Expression Omnibus (GEO) database. Differently expressed (DE) lncRNAs and mRNAs were identified by "limma" package.

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