3 results match your criteria: "China. 800026@hospital.cqmu.edu.cn.[Affiliation]"
Correction: Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.
Cell Commun Signal
June 2024
Department of Obstetrics and Gynecology, The University-Town Hospital of Chongqing Medical University, No. 55, Daxuecheng Middle Road, Chongqing, 401331, China.
Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.
Cell Commun Signal
May 2024
Department of Obstetrics and Gynecology, The University-Town Hospital of Chongqing Medical University, No. 55, Daxuecheng Middle Road, Chongqing, 401331, China.
Article Synopsis
- Intrauterine adhesion (IUA) is a severe cause of infertility due to damage to the endometrium, and stem cell therapy presents a potential treatment by either paracrine effects or transdifferentiation.
- The study involved co-culturing human amniotic mesenchymal stem cells (hAMSCs) with transformed endometrial stromal cells and assessing various molecular and histological markers after treatment in an IUA rat model.
- Results showed that hAMSCs significantly reduced collagen and fibronectin levels in damaged cells, improved endometrial gland counts, and decreased fibrosis, particularly noted after 6 days of co-culture.
Human amniotic mesenchymal stem cells combined with PPCNg facilitate injured endometrial regeneration.
Stem Cell Res Ther
January 2022
Department of Obstetrics and Gynecology, University-Town Hospital of Chongqing Medical University, No. 55, Daxuecheng Middle Road, Chongqing, 401331, China.
Background: Caused by the injury to the endometrial basal layer, intrauterine adhesions (IUA) are characterized by uterine cavity obliteration, leading to impaired fertility. Human amniotic mesenchymal stem cells (hAMSCs) have the potential to promote endometrial regeneration mainly through paracrine ability. PPCNg is a thermoresponsive biomaterial consisted of Poly (polyethylene glycol citrate-co-N-isopropylacrylamide) (PPCN) mixed with gelatin, which has been reported as a scaffold for stem cell transplantation.
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