Phase-contrast imaging with synchrotron hard X-ray of micro lesions of the cartilage of the femoral head in rabbits.

Background: To observe micro lesions on the cartilage of the rabbit femoral head using phase-contrast imaging with synchrotron hard X-ray and to prove that this method can be useful in the study of the degeneration of cartilage.

Methods: New Zealand white rabbits were used in a micro lesion model of rabbit femoral head cartilage. Bilateral femoral heads were excised from rabbits, and micro lesions were made on one side with a specially made knife with a blade 20 μm in width.

[An eighteen-year study on phenylketonuria].

A study on phenylketonuria (PKU) has been carried out in China-Japan Friendship Hospital since 1984. The results revealed that: (1) Totally 603 patients with PKU were diagnosed and treated in the hospital from October 1984 to September 2002. Among which 136 cases were identified by neonatal screening and treated within 3 months.

[Effect of alpha-difluoromethylornithine on growth characteristics and expression of ALT-04ag gene of human lung carcinoma cells].

Objective: To study the effect of polyamine biosynthesis inhibition on growth characteristics of human lung carcinoma cells and its correlation with the expression of human lung carcinoma associated antigen ALT-04ag gene.

Methods: The gene expression was detected by RT-PCR and immunocytochemical tests. The cell growth characteristics were studied by cell growth curves, morphological observation, FCM analysis and DNA electrophoresis.