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Hourly air pollution exposure and the onset of symptomatic arrhythmia: an individual-level case-crossover study in 322 Chinese cities.
CMAJ
May 2023
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment (Xue, Jiang, Kan, R. Chen), Fudan University, Shanghai, China; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine (Hu, Ge), Shanghai, China; Department of Cardiology (Xiang), General Hospital of Southern Theater Command of PLA, Guangzhou, China; Department of Environmental Health (H. Li), Harvard T.H. Chan School of Public Health, Boston, Mass.; Department of Cardiology (Fang), Huadong Hospital, Fudan University, Shanghai, China; Center for Coronary Artery Diseases (Yan), Chinese Academy of Medical Sciences in Shenzhen, Shenzhen, China; Center for Coronary Artery Diseases (Yan), Chinese Academy of Medical Sciences, Beijing, China; Department of Cardiology (J. Chen), Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; Department of Cardiology (W. Wang), Peking University People's Hospital, Beijing, China; Department of Cardiology (Su), Wuhan ASIA General Hospital, Wuhan, China; Department of Cardiology (Yu), The 2nd Affiliated Hospital, Harbin Medical University, The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; Department of Cardiology (Y. Wang), Xiamen Cardiovascular Hospital Xiamen University, Xiamen, China; Department of Cardiology (Xu), Shanghai Tenth People's Hospital, Shanghai, China; Heart Center and Beijing Key Laboratory of Hypertension (L. Wang), Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Emergency (C. Li), Tianjin Chest Hospital, Tianjin, China; Senior Department of Cardiology (Y. Chen), the Sixth Medical Center of PLA General Hospital, Beijing, China; Department of Epidemiology (Zhao), Beijing An Zhen Hospital, Capital Medical University; Beijing Institute of Heart, Lung and Blood Vessel Diseases (Zhao), Beijing, China; Department of Cardiology (Huo), Peking University First Hospital, Beijing, China
Article Synopsis
- The study investigates the link between hourly air pollution levels and the onset of acute symptomatic arrhythmias in China from 2015 to 2021, utilizing a nationwide case-crossover approach.
- Data was collected from over 190,000 patients and includes hourly air quality measurements of six pollutants, highlighting significant associations between increased pollution and higher incidences of atrial fibrillation, atrial flutter, and supraventricular tachycardia shortly after exposure.
- The results show a clear increased risk of arrhythmias associated with air pollution, particularly within the first 24 hours, with no clear threshold levels indicating a safe exposure limit.