Full-length transcriptome analysis of male and female gonads in Japanese Eel (Anguilla japonica).

Background: The Japanese eel (Anguilla japonica) holds significant economic value in East Asia, but limitations in understanding its reproductive biology have hindered advancements in artificial breeding techniques. Previous research has primarily focused on conserved sex differentiation genes, offering limited insights into the broader molecular mechanisms driving gonadal development and sexual dimorphism. To address these limitations, this study aims to investigate key genes and pathways involved in gonadal development through a comprehensive transcriptomic analysis of male and female eel gonads.

Design and mechanical analysis of a novel modular bionic earthworm robot with upright functionality.

With the escalating demand for exploration within confined spaces, bionic design methodologies have attracted considerable attention from researchers, primarily due to the intrinsic limitations of human access to hazardous environments. However, contemporary bionic robots primarily attain linear motion through the axial radial deformation of their body segments, thereby lacking the upright functionality that is characteristic of these organisms. In response to the limitations associated with current bionic earthworm robots concerning upright capability and stiffness modulation, we propose an innovative bionic robot that incorporates upright functionality and programmable stiffness.

Equilibrium study of logistics demand and logistics resource allocation in Guangdong Province.

Logistics serve as a vital link between production and consumption. The balanced allocation of logistics demand and resources can promote the harmonious development of the logistics system, thereby fostering regional economic growth. As a leading region in China's reform and opening-up, Guangdong Province has experienced high economic growth.

Robot-assisted PFNA surgery improves clinical outcomes in the treatment of unstable femoral intertrochanteric fractures in elderly patients compared with traditional PFNA surgery.

To assess the clinical outcomes of robot-assisted proximal femoral nail antirotation (PFNA) surgery in elderly patients with unstable femoral intertrochanteric fractures (UFIFs). 151 patients who underwent UFIF and PFNA surgery between January 2020 and May 2024 were analyzed retrospectively. Of these, 78 patients were treated with traditional PFNA surgery (control group), and 73 patients were treated with robot-assisted PFNA surgery (observation group).

An optimized lightweight real-time detection network model for IoT embedded devices.

With the rapid development of Internet of Things (IoT) technology, embedded devices in various computer vision scenarios can realize real-time target detection and recognition tasks, such as intelligent manufacturing, automatic driving, smart home, and so on. YOLOv8, as an advanced deep learning model in the field of target detection, has attracted much attention for its excellent detection speed, high precision, and multi-task processing capability. However, since IoT embedded devices typically own limited computing resources, direct deployment of YOLOv8 is a big challenge, especially for real-time detection tasks.

Chromosome level genome assembly of 'Wanfeng' almond (Prunus dulcis).

We assembled a chromosome-level genome of Chinese native 'Wanfeng' almond, with a size of 288.53 Mb and a contig N50 of 30.48 Mb.

Versatile nitrate-respiring heterotrophs are previously concealed contributors to sulfur cycle.

Heterotrophic denitrifiers play crucial roles in global carbon and nitrogen cycling. However, their inability to oxidize sulfide renders them vulnerable to this toxic molecule, which inhibits the key enzymatic reaction responsible for reducing nitrous oxide (NO), thereby raising greenhouse gas emissions. Here, we applied microcosm incubations, community-isotope-corrected DNA stable-isotope probing, and metagenomics to characterize a cohort of heterotrophic denitrifiers in estuarine sediments that thrive by coupling sulfur oxidation with denitrification through chemolithoheterotrophic metabolism.

The TCP transcription factor TAC8 positively regulates the tiller angle in rice (Oryza sativa L.).

The tiller angle, one of the critical factors that determine the rice plant type, is closely related to rice yield. An appropriate rice tiller angle can improve rice photosynthetic efficiency and increase yields. In this study, we identified a transcription factor, TILLRE ANGLE CONTROL 8 (TAC8), that is highly expressed in the rice tiller base and positively regulates the tiller angle by regulating cell length and endogenous auxin content; TAC8 encodes a TEOSINTE BRANCHED1/CYCLOIDEA/PCF transcriptional activator that is highly expressed in the nucleus.

Dexmedetomidine alleviates acute kidney injury in a rat model of veno-arterial extracorporeal membrane oxygenation.

Background: Although extracorporeal membrane oxygenation (ECMO) is an effective technique for life support, the incidence of acute kidney injury (AKI) during ECMO support remains high. Dexmedetomidine (DEX), which has been widely used for sedation during ECMO, possesses several properties that help reduce the occurrence of AKI. This study aimed to investigate the protective effect of DEX on kidney function during ECMO.

Diverse Annulations of Alkyl(phenyl)phosphinic Chlorides and Imines.

The reactivity of alkyl(aryl)phosphinic chlorides and imines was investigated in the presence of a base. The results indicated that allyl/benzyl(aryl)phosphinic chlorides gave rise to 1,2-azaphosphines (δ-phostims), while nonbenzylic alkyl(aryl)phosphinic chlorides produced the corresponding β-phosphinolactams (β-phostims) in their reaction with cyclic dibenzo[,][1,4]oxazepines, whereas steric electron-rich arylmethyl(aryl)phosphinic chlorides generated [2 + 2 + 2] annuloadducts in some cases. The current investigation provides useful insight into the reactivity of phosphinic chlorides and imines.

Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2-Ethynylthiazole-4-carboxamide as Electrophilic Warhead.

A highly selective ferroptosis inducer with drug-like properties can significantly advance the research on inducing ferroptosis for anticancer treatment. We previously reported a highly active GPX4 inhibitor , but its activity and stability need further improvement. In this work, a novel GPX4 inhibitor with more potent cytotoxicity (IC = 0.

A Novel Endophytic Fungus R-423 for the Control of Root Rot in Pigeon Pea as Reflected by the Alleviation of Reactive Oxygen Species-Mediated Host Defense Responses.

root rot is a devastating fungal disease that causes significant yield losses in legume crops. A novel endophytic fungus R-423 isolated from pigeon pea had a significant antagonistic capacity against . R-423 extracts could inhibit growth and cause it to die.

Dynamic Behaviors of Droplet Impacts in Dropwise Condensation on Horizontal Tube Bundles.

Dropwise condensation offers substantial heat transfer advantages over filmwise condensation, enhancing the industrial condenser efficiency and reducing energy losses. However, the dynamics of condensate droplets on horizontal tube bundles remains complex and insufficiently studied. This paper presents a detailed investigation of the impact of dynamic behaviors of condensate droplets by numerical simulation using the Volume of Fluid model.

Green lignocellulose-nanofibers-based molecular imprinting membranes for baicalin selective adsorption.

Lignocellulosic nanofibers (LCNF), blending nano-scale cellulose and lignin, were carboxylated and integrated with PVA and baicalin to create a molecularly imprinted membrane (CLCNF-MINM). This innovation, leveraging reactive deep eutectic solvent technology and electrospinning, boosts adsorption capacity by 12.3-21.

Duck feather inspired hydrophobic carboxymethyl cellulose/gelatin film for intelligent and active food packaging.

Inspired by the superhydrophobic characteristics of duck feathers this research introduced an intelligent, responsive, and eco-friendly food packaging film constructed from carboxymethyl cellulose (CMC) and gelatin (Gel). The film successfully mimics the asymmetric, bionic, barbed structure of a duck feather, offering outstanding hydrophobicity and moisture vapor resistance characteristics. Moreover, the bionic film demonstrated good mechanical strength, film-forming ability and biodegradability.

A biomass-based "double-encapsulation structure" heightens the flame retardancy, antimicrobial effectiveness, and hydrophobicity of cotton fabric.

Due to the non-renewable nature of petroleum resources, there has been a notable shift toward utilizing biomass materials to confer flame retardant properties to cotton fabrics. However, endow solely with single function cannot meet the application requirements across various fields. Therefore, there is considerable impetus to develop multifunctional cotton fabrics integrating flame retardant, antimicrobial, and hydrophobic properties sourced from biomass.

Microfluidic design and preparation of hydrogel microcapsules of Mesona chinensis polysaccharide: Characterization, pH-responsive behavior and gastrointestinal protection for Lactobacillus plantarum.

Probiotics have brought many health benefits to the human body. However, their viability during gastrointestinal transit is a concern. Therefore, this study selected Mesona chinensis polysaccharide (MCP), an edible natural polysaccharide, and constructed a new type of microcapsules using MCP as raw material to prepare cross-linked calcium ions through a microfluidic system as an ideal intestinal targeting carrier to achieve precise delivery of bioactive substances.

Caps-ac4C: an effective computational framework for identifying N4-acetylcytidine sites in human mRNA based on deep learning.

N4-acetylcytidine (ac4C) is a crucial post-transcriptional modification in human mRNA, involving the acetylation of the nitrogen atom at the fourth position of cytidine. This modification, catalyzed by N-acetyltransferases such as NAT10, is primarily found in mRNA's coding regions and enhances translation efficiency and mRNA stability. ac4C is closely associated with various diseases, including cancer.

Spatiotemporal changes of vegetation in the northern foothills of Qinling Mountains based on kNDVI considering climate time-lag effects and human activities.

Vegetation is fundamental to regulating the climate system and ensuring carbon balance. Recognizing the effects of climate change (CC) and human activities (HA) is vital for understanding shifts in vegetation. However, climate time-lag effects are rarely measured, resulting in an inadequate assessment of CC's effects on vegetation dynamics.

High-Throughput Zebrafish Screening Reveals Cardiotoxic Effects of Organophosphate Flame Retardants.

The toxicity of organophosphorus flame retardants (OPFRs) remains poorly understood, despite their widespread environmental presence and potential risks to human and ecological health. This study aimed to characterize the cardiovascular developmental toxicity of OPFRs using a high-throughput zebrafish screening model. Over thirty representative OPFRs, classified into three major groups-alkyl, aryl, and halogenated-were evaluated.

Centurial sedimentary record of Cd sources and deposition in Chaohu Lake: insights from Cd stable isotopes.

Understanding the sources and deposition processes of cadmium (Cd) in freshwater lakes is essential for effective pollution management. This study investigated the Cd concentrations and isotopes in a sediment core from Chaohu Lake, spanning the past 200 years. The results revealed that the Cd concentrations in the sediments decreased with depth, ranging from 1.

A critical review of microbial profiles in black and odorous waters.

Black and odorous waters (BOWs) are a serious environmental problem frequently reported over the past few decades. Microorganisms are identified as implementors of the black and odorous phenomenon, which play a crucial role in the decomposition and transformation of pollutants within the BOWs. However, the information on the role of microorganisms in BOWs remains elusive.

Non-coding RNAs and regulatory networks involved in the Ameson portunus (Microsporidia)-Portunus trituberculatus interaction.

Ameson portunus, the causative agent of "toothpaste disease" in Portunus trituberculatus and "slurry-like syndrome" in Scylla paramamosain, has resulted in considerable economic losses in the marine crab aquaculture industry in China. Practical control strategies are yet unavailable. Non-coding RNAs (ncRNAs) are crucial components of gene regulation of intracellular parasites, however, their roles in regulating the microsporidia-host interaction remain limited.

Comprehensive transcriptome analysis reveals lncRNA-mRNA interactions and immune response mechanisms in Mytilus coruscus upon Vibrio alginolyticus infection.

Long non-coding RNAs (lncRNAs) play diverse biological roles within cells. Despite not encoding proteins, they are crucial in regulating gene expression, chromatin structure and function, cell differentiation and development, and the occurrence of diseases. Vibrio alginolyticus (V.