Dual-plasmonic eccentric nanostructure with prominent colorimetric and photothermal performance to detect zearalenone by dual signal immunochromatography assay.

In the study, an eccentric heterogeneous core-shell nanomaterial Au@CuSe was simply and rapidly synthesized. This novel nano-structure exhibits superior colorimetric intensity, enhanced antibody coupling efficiency, and strong broadband absorption across the visible to near-infrared spectrum, with a photothermal conversion efficiency of 59.40%.

A Milk Extracellular Vesicle-Based Nanoplatform Enhances Combination Therapy Against Multidrug-Resistant Bacterial Infections.

The increasing occurrence of infections caused by multidrug-resistant (MDR) bacteria drives the need for new antibacterial drugs. Due to the current lack of antibiotic discovery and development, new strategies to fight MDR bacteria are urgently needed. Efforts to develop new antibiotic adjuvants to increase the effectiveness of existing antibiotics and design delivery systems are essential to address this issue.

Sulfhydrylation of chlorothalonil in pak choi from cultivation to sample analysis and exposure risk assessment.

The rapid sulfhydrylation of chlorothalonil (CHT) in sulfur-rich vegetable matrices was observed in our previous study. However, the formation pathway, residual behavior, and toxicity of sulfhydrylated CHT remain unclear. In this study, we reveal that 4-sulfhydryl chlorothalonil (4-SH-CHT) can be formed by the reaction of CHT with HS species.

One Health Approach of Enterococcal Population Structure and Antibacterial Resistance Along the Food Chain - Four PLADs, China, 2015-2022.

Introduction: Enterococci are considered opportunistic pathogens. However, they can serve as a reservoir of antibacterial resistance (ABR) traits and transfer these to humans through the food chain.

Methods: Antibiotic susceptibility testing and multilocus sequence typing were used to characterize the ABR and population structure of 488 enterococcal isolates recovered along the food chain from four provincial-level administrative divisions (PLADs) in China.

Characterization and Implications of the Regionally Prevalent ST8333 Strains of Serotype 4,[5],12:i: - China, 2017-2023.

What Is Already Known About This Topic?: is a significant foodborne pathogen responsible for millions of infections and thousands of deaths worldwide each year. The increasing prevalence of the ST34 serotype 4,5,12:i:-(. 4,[5],12:i:-) poses a substantial public health threat in China.

Phenotypic vs. Genetic Mismatch of BMI and Type 2 Diabetes: Evidence from Two Perspective Cohort Studies.

Little is known about the population-based mismatch between phenotypic and genetic BMI (BMI-PGM) and its association with type 2 diabetes. We therefore used data from the China Kadoorie Biobank and UK Biobank and calculated BMI-PGM for each participant as the difference between the percentile for adjusted BMI at baseline and the percentile for adjusted polygenic risk score for BMI. Participants were categorized into discordantly low (BMI-PGM< the 1st quartile), concordant (the 1st quartile ≤BMI-PGM View Article and Find Full Text PDF

Effect of UV-C irradiation treatment on mycotoxins production in Fusarium species inoculated wheat seeds during wheat germination.

Wheat is a most important food crop worldwide. Wheat is reported to be susceptible to a variety of fungi, which could induce huge economic losses and the contamination of potential mycotoxins could bring serious toxic effects. In this work, UV-C irradiation treatment on Fusarium infected wheat seeds during germination was investigated.

Carried by a Transferable Plasmid in a Strain Isolated from Healthy Individuals.

Objective: Our study aimed to conduct genomic characterization of strains carrying the gene in the intestinal tract of healthy individuals. The objectives were to underscore the importance of genomic surveillance for drug resistance in both commensal and pathogenic bacteria among healthy populations, and to establish protocols for regulating drug resistance plasmids based on the completion of a comprehensive map of drug resistance plasmid genomes.

Methods: We performed antimicrobial susceptibility testing and employed second- and third-generation sequencing techniques to analyze strains harboring the gene, to surveil drug-resistant bacteria in the intestines of healthy subjects.

Amorphous cassava starch/spirulina protein mixtures stabilized Pickering emulsions: Preparation and stability.

This study explored stabilized emulsions using cassava starch (CS) and spirulina protein (SP) mixtures, targeting microbial proteins as potential replacements for animal proteins in food stability applications. The final viscosity and enthalpy change of the CS/SP mixtures decreased from 3.78 to 1.

Modifying effects of prenatal exposure to rare earth elements on birth outcomes through maternal thyroid function in early pregnancy.

The potential health effects of exposure to rare earth elements (REEs) remain largely unexplored. This prospective cohort study aimed to elucidate the association between early pregnancy REE exposure and maternal thyroid function, as well as neonatal birth outcomes, in a cohort of pregnant women in Beijing, China. Additionally, the study explored the mediating role of thyroid homeostasis in the effects of REE exposure.

[Associations of plasma acylcarnitine and bile acid levels with incidence of coronary heart disease in Chinese adults].

To explore the associations of plasma acylcarnitine and bile acid levels with the risk of incident coronary heart disease (CHD) in Chinese adults. The baseline survey of China Kadoorie Biobank (CKB) took place in 10 areas across China during 2004-2008, and the first resurvey took place from July to October 2008, with collection of data via questionnaire, physical examination and blood samples. The current study was based on 2 159 individuals with targeted mass spectrometry metabolomic measurements from the first resurvey of CKB.

Associations of long-term nitrogen dioxide exposure with a wide spectrum of diseases: a prospective cohort study of 0·5 million Chinese adults.

Background: Little evidence is available on the long-term health effects of nitrogen dioxide (NO) in low-income and middle-income populations. We investigated the associations of long-term NO exposure with the incidence of a wide spectrum of disease outcomes, based on data from the China Kadoorie Biobank.

Methods: This prospective cohort study involved 512 724 Chinese adults aged 30-79 years recruited from ten areas of China during 2004-08.

Complete genome sequence provides information on quorum sensing related spoilage and virulence of Aeromonas salmonicida GMT3 isolated from spoiled sturgeon.

Foodborne bacteria can pose a threat to the public health due to their spoilage and virulence potential, which can be regulated by quorum sensing (QS) system. In the study, we isolated a spoilage bacteria strain Aeromonas salmonicida GMT3 from refrigerated sturgeon. The complete genome of A.

Assessing foodborne outbreak risk in Chinese households: A national survey analysis of pork handling practices.

Objective: This study aimed to assess the risk of foodborne outbreaks associated with household food handling practices in China and identify the consumer groups that are at higher risk for foodborne outbreaks.

Methods: A national survey of household pork handling practices was conducted in China. The risk of foodborne outbreaks stemming from consumers' improper handling practices was assessed utilizing the Weighted Harmonic Outbreak Prevention Index (WHOPI).

High carriage and possible hidden spread of multidrug-resistant Salmonella among asymptomatic workers in Yulin, China.

Food workers have frequent contact with unprocessed foods, but their carriage of Salmonella and potential influence on public health have not been comprehensively assessed. We investigated Salmonella carriage among food workers compared with non-food workers based on occupational health screening of 260,315 asymptomatic workers over an 8-year surveillance period in Yulin, China. We confirmed that healthy carriers serve as natural reservoirs for Salmonella, with higher carriage rates in food workers than non-food workers.

The burden of cancer attributable to dietary dioxins and dioxin-like compounds exposure in China, 2000-2020.

Dioxin is a typical class of persistent organic pollutants (POPs) that could cause cancer. In China, the contribution of dietary dioxins to the cancer burden remains underexplored. This study evaluates the cancer risk and burden due to dietary dioxins and dioxin-like compounds among Chinese residents from 2000 to 2020.

Risk factors for severe COPD exacerbation in Chinese adults.

Severe exacerbation is the predominant cause of COPD hospitalisation. We investigated sex-specific risk factors of severe exacerbation and explored the potential interactions of regions, smoking status, and age.The present study included 13,641 males and 13,051 females with spirometry-defined COPD at baseline from the China Kadoorie Biobank.

Organophosphorus flame retardants in infant's diets from Beijing, China: Detection and risk assessment.

As a group of widely used flame retardants, organophosphate esters (OPEs) and their metabolites, organophosphate diesters (di-OPEs), have been widely detected in various environmental media and human samples. However, the information on dietary exposure to OPEs for lactating infants is still limited. Here, 38 OPEs and 10 di-OPEs were monitored in 110 infant formula samples and 122 breast milk samples collected in Beijing, China.

The characteristic and bio-accessibility evaluation of mercury species in various kinds of seafood collected from Fujian of China for mercury risk assessment.

Seafood consumption is the major source of total Hg (tHg) and methyl mercury (MeHg) for humans. Lack of broad-representative bio-accessibility of mercury species makes accurate assessment on health risk of seafood's mercury impossible. Herein, the concentrations and in vitro bio-accessibilities of mercury species in 93 seafood samples with 71 different species were extensively investigated.