4 results match your criteria: "China Medical University the Fourth People's Hospital of Shenyang[Affiliation]"
Evaluating the Efficacy of Conbercept and Dexamethasone Implants Sequentially in the Treatment of Refractory Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO): A One-Year Follow-Up Study.
Clin Ophthalmol
September 2024
Department of Ophthalmology, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
Article Synopsis
- This research aimed to evaluate the effectiveness and safety of using Conbercept injections followed by dexamethasone implants to treat stubborn macular edema from central retinal vein occlusion.
- The study involved 34 patients, tracking their central retinal thickness, visual acuity, and intraocular pressure before and after treatment over a year.
- Results showed that while central retinal thickness and intraocular pressure improved significantly, there were no notable changes in visual acuity or vessel density, suggesting a mixed outcome for the treatment regimen.
Microwave treatment ameliorates beaded eyelid papules caused by lipoid proteinosis.
Pediatr Dermatol
November 2024
Department of Dermatology, The First Hospital of China Medical University, Shenyang, China.
Article Synopsis
- An 8-year-old girl had white bumps on her eyelids caused by lipoid proteinosis, a rare skin condition.
- Microwave therapy was used and led to a significant decrease in these eyelid lesions.
- The case also identified two new genetic variants in the ECM1 gene, which is linked to this condition.
Switching to Conbercept in Diabetic Macular Edema After Unsatisfactory Response to Previous Intravitreal Injection of Ranibizumab.
Clin Ophthalmol
November 2023
Department of Ophthalmology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
Objective: To assess the functional and anatomical effects of transitioning to conbercept intravitreal injection (IVC) treatment in patients with diabetic macular edema (DME) who had inadequate responses to prior anti-vascular endothelial growth factor (anti-VEGF) injections.
Methods: We retrospectively included eyes with persistent DME after at least 3 injections of intravitreal ranibizumab (IVR). The analysis included the assessment of best corrected visual acuity (BCVA) and central macular thickness (CMT) during 6 months after the switch.
Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis.
BMC Neurosci
November 2022
Department of Ophthalmology, China Medical University the Fourth People's Hospital of Shenyang, No.20 Huang He Street, Huang Gu District, Shenyang City, 110031, Liaoning Province, China.
Background: Retinal ganglion cells (RGCs) are important retinal neurons that connect visual receptors to the brain, and lysine-specific demethylase 1 (LSD1) is implicated in the development of RGCs. This study expounded the mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation (OGD/R)-induced pyroptosis of RGCs.
Methods: Mouse RGCs underwent OGD/R exposure, and then RGC viability was examined using the cell counting kit-8 method.