2 results match your criteria: "China Medical University Hospital of Boshan District[Affiliation]"
Genetic role of CYP4A11 polymorphisms in the risk of developing cardiovascular and cerebrovascular diseases.
Ann Hum Genet
November 2018
China Medical University Hospital of Boshan District, Zibo City, Shandong, 255200, People's Republic of China.
Article Synopsis
- The study explores the genetic impact of three specific CYP4A11 polymorphisms (rs9332978 A/G, rs1126742 T/C, and rs9333025 G/A) on the likelihood of cardiovascular and cerebrovascular diseases.* -
- A meta-analysis of 22 case-control studies was conducted, revealing that rs9332978 was linked to a higher risk of these diseases, particularly in individuals with hypertension, while rs1126742 showed significant differences in risk across various populations.* -
- The findings suggest that rs1126742 is a notable risk factor for hypertension in Caucasians, and that the AG genotype of rs9332978 increases disease risk, whereas the AA genotype of rs9333025 may
Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) rs1558139, rs2108622 polymorphisms and susceptibility to several cardiovascular and cerebrovascular diseases.
BMC Cardiovasc Disord
February 2018
China Medical University Hospital of Boshan District, Zibo City, Shandong, 255200, People's Republic of China.
Background: Inconsistent conclusions have been reported for the genetic relationship between CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) polymorphisms and the susceptibility to cardiovascular and cerebrovascular diseases.
Methods: We performed a meta-analysis to assess the potential role of rs1558139 C/T and rs2108622 G/A polymorphisms of CYP4F2 in the risks of cardiovascular and cerebrovascular diseases. The retrieval of four databases, including PubMed, Web of Science (WOS), China National Knowledge Infrastructure (CNKI) and WANFANG DATA, was conducted.