1 results match your criteria: "China Jiangsu Province Traditional Chinese Medicine Hospital[Affiliation]"
Association between CYP1B1 gene polymorphisms and risk factors and susceptibility to laryngeal cancer.
Med Sci Monit
January 2015
Department of Otolaryngology - Head and Neck Surgery, China Jiangsu Province Traditional Chinese Medicine Hospital, Nanjing, Jiangsu, China (mainland).
Background: The aim of this study was to investigate the association between polymorphism of the cytochrome P450 1B1 (CYP1B1) gene, a metabolic enzyme gene, and the susceptibility to laryngeal cancer among the Chinese Han population.
Material/methods: In a case-control study, we investigated polymorphisms in the CYP1B1 gene (rs10012, rs1056827, and rs1056836) with a real-time quantitative polymerase chain reaction (PCR) assay (TaqMan). The study was conducted with 300 Chinese Han patients with laryngeal cancer and 300 healthy Chinese Han subjects in a control group.