Association of life's essential 8 and inflammatory biomarkers with nutritional anemia in UK adults.

Several modifiable health factors in Life's Essential 8 (LE8) are linked to nutritional anemia and can assess overall cardiovascular health (CVH). This study explored the associations of CVH measured by LE8 score with nutritional anemia and iron deficiency anemia (IDA), including the mediating role of inflammatory biomarkers. This prospective cohort study included 181,069 participants from UK Biobank.

Using monitoring and simulation to analyze the failure characteristics of multizone landslides controlled by faults: a case study.

Slopes influenced by multiple faults are prone to large-scale landslides triggered by multi-regional failures. Understanding the failure process and sequence is essential for the sustainable development of mining operations. This paper presents a method combining InSAR monitoring and numerical simulation to analyze the failure processes of slopes affected by multiple faults.

Carbon-supported Fe single atom nanozymes with long-lasting ROS generation and high NIR photothermal performance for synergistic cancer therapy.

Synergistic therapy combining photothermal therapy (PTT) and chemodynamic therapy (CDT) has proven to be a highly effective strategy for cancer treatment. However, PTT heavily relies on the accumulation of therapeutic agents at the tumor site. The peroxidase (POD) activity of common catalysts can be rapidly exhausted during the accumulation process, prior to laser intervention, thereby diminishing the synergistic enhancement effect of the combined therapy.

Hyaluronic acid modified metal-organic frameworks loading cisplatin achieve combined chemodynamic therapy and chemotherapy for lung cancer.

As one of the most commonly used chemotherapeutic agents in clinical practice, cisplatin is unable to selectively accumulate in tumor tissue due to its lack of targeting ability, leading to increased systemic toxicities. Additionally, the effectiveness of monotherapy is greatly limited. Therefore, the development of new cisplatin-based drug delivery systems is essential to improve the effectiveness of tumor treatment.

FeS@BC prepared from natural pyrite and biomass as peroxydisulfate activator for sulfadiazine degradation.

The efficient degradation of SAs is a significant challenge for the treatment of wastewater. To address this, the FeS@BC was prepared by calcining a mixture of pyrite and biomass, and used to activate peroxydisulfate (PDS) to degrade sulfadiazine (SDZ). The effect of carbon sources (wheat straw, rice husk, and corn cob) on catalytic activity of FeS@BC were investigated by Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), total Fe dissolution and free radical quantification.

Multifaceted interplays between the essential players and lipid peroxidation in ferroptosis.

Ferroptosis, a type of programmed cell death, represents a distinct paradigm in cell biology. It is characterized by the iron-dependent accumulation of reactive oxygen species, which induce lipid peroxidation (LPO), and is orchestrated by the interplay between iron, lipid peroxides, and glutathione. In this review, we emphasize the frequently overlooked role of iron in LPO beyond the classical iron-driven Fenton reaction in several crucial processes that regulate cellular iron homeostasis, including iron intake and export as well as ferritinophagy, and the emerging roles of endoplasmic reticulum-resident flavoprotein oxidoreductases, especially P450 oxidoreductases, in modulating LPO.

The role of sulfidated zero-valent iron in enhancing anaerobic digestion of waste activated sludge.

Zero-valent iron (ZVI) has been confirmed in enhancing methane production by improving interspecies electron transfer during anaerobic digestion (AD) of waste activated sludge (WAS). In this study, we suppose that sulfidated zero-valent iron (S-ZVI), a semiconductor material, has better property of electron transfer in AD process. Based on two-phase anaerobic digestion process, nitrite and S-ZVI were used separately for improving acidogenic phase and methanogenic phase of anaerobic sludge digestion.

Heterotrophic denitrification enhancement via effective organic matter degradation driven by suitable iron dosage in sediment.

The control of internal pollution was important throughout the restoration of the lake, especially the removal of sediment internal nitrogen. Experiments involving incubation were conducted in this study to investigate the effects of iron remediation on nitrogen in both water and sediment. Adding iron with varying dosage had different effects on the nutrients content and other properties of water and sediment in remediation.

Spatial and temporal distribution patterns and conservation status of seagrasses in the Yellow Sea and Bohai Sea.

Seagrasses represent a significant class of marine foundation species, yet the distribution of seagrasses in the Yellow Sea and Bohai Sea remains uncertain, thereby impeding the efficacy of conservation and restoration practices. In this study, the spatial and temporal distribution pattern of seagrasses was simulated by the MaxEnt model based on the construction of marine environment and human activity datasets. The main controlling factors affecting seagrass potential distribution were analyzed, and the response of seagrass distribution to global change was clarified.

Ferroptosis: A New Pathway in the Interaction between Gut Microbiota and Multiple Sclerosis.

Multiple sclerosis (MS) is a chronic autoimmune disorder marked by neuroinflammation, demyelination, and neuronal damage. Recent advancements highlight a novel interaction between iron-dependent cell death, known as ferroptosis, and gut microbiota, which may significantly influences the pathophysiology of MS. Ferroptosis, driven by lipid peroxidation and tightly linked to iron metabolism, is a pivotal contributor to the oxidative stress observed in MS.

Association Between Protein-Rich Foods, Nutritional Supplements, and Age of Natural Menopause and Its Symptoms.

Objective: To investigate the relationship between protein-rich foods, various nutritional supplements, and age of natural menopause and its symptoms.

Methods: This study was a large-scale cross-sectional survey. A multi-stage stratified random sampling method was used to select a sample of 52,347 residents aged 35-60 years from 26 districts/counties across 13 cities in 12 provinces in China.

The Fluorescent Detection of Alkaline Phosphatase Based on Iron Nanoclusters and a Manganese Dioxide Nanosheet.

Fluorescent iron nanoclusters are emerging fluorescent nanomaterials. Herein, we synthesized hemoglobin-coated iron nanoclusters (Hb-Fe NCs) with a significant fluorescence emission peak at 615 nm and investigated the inner-filter effect of fluorescence induced by a manganese dioxide nanosheet (MnO NS). The fluorescence quenching of Hb-Fe NCs by a MnO NS can be significantly reversed by the addition of ascorbic acid.

Iron-Catalyzed Cross-Dehydrogenative Coupling.

This review highlights significant advances in iron-catalyzed cross-dehydrogenative coupling (CDC), a method pivotal for forming carbon-carbon (C-C) bonds directly from C-H bonds. This technique uses iron-a naturally abundant, inexpensive, and environmentally benign transition metal-as a catalyst to facilitate the coupling of two unfunctionalized C-H bonds. This method stands out for avoiding pre-functionalized substrates, reducing both waste and cost in organic synthesis.

In Situ EBSD Observation and Numerical Simulation of Microstructure Evolution and Strain Localization of DP780 Dual-Phase Steel.

To reveal the microstructural evolution and stress-strain distribution of 780 MPa-grade ferrite/martensite dual-phase steel during a uniaxial tensile deformation process, the plastic deformation behavior under uniaxial tension was studied using in situ EBSD and crystal plastic finite element method (CPFEM). The results showed that the geometrically necessary dislocations (GND) in ferrite accumulated continuously, which is conducive to the formation of grain boundaries, but the texture distribution did not change significantly. The average misorientation angle decreased and the proportion of low-angle grain boundaries increased with the increase of strain.

The Multiple Effects of RE Element Addition in Non-Oriented Silicon Steel.

High-grade non-oriented silicon steel with high magnetic induction and low iron loss produced with low carbon emissions is crucial for the development of new energy and energy-saving motors. In this paper, the trace mixed rare earth (RE) elements exhibit a great potential to enhance magnetic properties in a lower carbon emission process by multiple effects on microstructure, texture, and inclusion in non-oriented silicon steel. With the trace-doped RE elements (0.

Construction and Properties of Wood-Based Tannin-Iron-Complexed Photothermal Material .@Fe-GA for Solar Seawater Desalination System.

Desalinating seawater is a crucial method for addressing the shortage of freshwater resources. High-efficiency, low-cost, and environmentally friendly desalination technologies are key issues that urgently need to be addressed. This work used as a matrix material and prepared @Fe-GA through a complexation reaction to enhance the water evaporation rate and photothermal conversion efficiency of seawater desalination.

The Microstructures, Mechanical Properties, and Energetic Characteristics of a Novel Dual-Phase TiZrWMo High-Entropy Alloy.

High-energy structural materials (ESMs) integrate a high energy density with rapid energy release, offering promising applications in advanced technologies. In this study, a novel dual-phase TiZrWMo high-entropy alloy (HEA) was synthesized and evaluated as a potential ESM. The alloy exhibited a body-centered cubic (BCC) matrix with Mo-W-rich BCC precipitates of varying sizes, which increased proportionally with the W content.

Performance Evaluation of Stabilized Soils with Selected Common Waste Materials of Rice Husk Ash, Steel Slag and Iron Tailing Powder.

Soil stabilization technology has been applied for a long time in the infrastructure construction field. Currently, the use of waste materials as stabilizer is growing in attention, because it promises to develop green and high-performance soil stabilization efficiency. In this work, three common waste materials, including rice husk ash (RHA), steel slag (SS) and iron tailing (IT) powder, were selected and synergistically utilized with cement to prepare stabilized soil.

The Influence of Alkali Metals on the Sintering Mineralization Process of Iron Ore.

To investigate the influence of alkali metal compounds in different forms on the sintering mineralization process of iron ore, the basic sintering characteristics of iron ore with alkali metal contents ranging from 0 to 4% were measured using the micro-sintering method, and the influence mechanism was analyzed using thermodynamic analysis and first-principles calculations. The results showed that (1) the addition of KCl/NaCl increased the lowest assimilation temperature (LAT) and the index of liquid-phase fluidity (ILF), while that of KCO/NaCO decreased the LAT but increased the ILF of iron ore. (2) The pores formed by the volatilization of KCl/NaCl suppressed the diffusion of Fe and Ca, which inhibited the formation of silico-ferrite of calcium and aluminum (SFCA).

Effect of Elemental Iron Containing Bauxite Residue Obtained After Electroreduction on High-Pressure Alkaline Leaching of Boehmitic Bauxite and Subsequent Thickening Rate.

The use of reduction leaching in the production of alumina from bauxite by the Bayer process in order to decrease the amount of waste (bauxite residue) by adding elemental iron or aluminum, as well as Fe salts and organic compounds in the stage of high-pressure leaching, requires the purchase of relatively expensive reagents in large quantities. The aim of this study was to investigate the possibility of the use of electrolytically reduced bauxite residue (BR) as a substitute for these reagents. Reduced BR was obtained from Al-goethite containing BR using a bulk cathode in alkaline suspension.

Efflux Pumps and Porins Enhance Bacterial Tolerance to Phenolic Compounds by Inhibiting Hydroxyl Radical Generation.

Phenolic compounds are industrially versatile chemicals that have been successfully produced in microbial cell factories. Unfortunately, most phenolic compounds are highly toxic to cells in specific cellular environments or above a particular concentration because they form a complex with iron and promote hydroxyl radical production in Fenton reactions, resulting in the ferroptosis of cells. Here, we demonstrated that overexpression of efflux pumps and porins, including porins LamB and OmpN, and efflux pumps EmrAB, MdtABC, and SrpB, can enhance phloroglucinol (PG) tolerance by inhibiting the generation of hydroxyl radicals.

Quorum Sensing Mediates Interaction with In Vitro.

and are opportunistic pathogens that cause severe infections in hospitals, and their co-infections are increasingly reported. The interspecies interactions between these two bacterial species and their potential impacts on infections are largely unexplored. In this study, we first demonstrated that inhibits the growth of by iron chelating via quorum sensing.

Fungi in the Gut Microbiota: Interactions, Homeostasis, and Host Physiology.

The mammalian gastrointestinal tract is a stage for dynamic inter-kingdom interactions among bacteria, fungi, viruses, and protozoa, which collectively shape the gut micro-ecology and influence host physiology. Despite being a modest fraction, the fungal community, also referred to as mycobiota, represents a critical component of the gut microbiota. Emerging evidence suggests that fungi act as early colonizers of the intestine, exerting a lasting influence on gut development.

Bioremediation of Heavy Metal-Contaminated Solution and Aged Refuse by Microbially Induced Calcium Carbonate Precipitation: Further Insights into .

Recently, the ability of microbial-induced calcium carbonate precipitation (MICP) to remediate heavy metals has been widely explored. was selected to remediate heavy metal-contaminated solution and aged refuse, exploring the feasibility of bioremediation of heavy metals and analyzing the changes in heavy metal forms before and after bioremediation, as well as the mechanism of remediation. The results showed that achieved remediation rates of 95%, 84%, 97%, and 98% for Cd, Pb, Zn, and Cr (III) in contaminated solution, respectively.

The Effect of Channel Layer Thickness on the Performance of GaN HEMTs for RF Applications.

In this paper, AlGaN/GaN high electron mobility transistors (HEMTs) with different thicknesses of unintentional doping GaN (UID-GaN) channels were compared and discussed. In order to discuss the effect of different thicknesses of the UID-GaN layer on iron-doped tails, both AlGaN/GaN HEMTs share the same 200 nm GaN buffer layer with an Fe-doped concentration of 8 × 10 cm. Due to the different thicknesses of the UID-GaN layer, the concentration of Fe trails reaching the two-dimensional electron gas (2DEG) varies.