A twenty-year dataset of hourly energy generation and consumption from district campus building energy systems.

Distributed energy resources (DERs) would play a crucial role in the transition towards decentralized and decarbonized energy systems. However, due to the limited availability of long-term, high-resolution datasets, there has been little research on the descriptive analysis of distributed energy systems throughout the lifespan of distributed power generators and beyond. To address this challenge, this study has collected and described a twenty-year dataset (from 2002 to 2021) consisting of hourly energy generation and consumption profiles from a campus distributed energy system, covering the entire lifespan of on-site generators.

Comparative 3D finite element analysis of intramedullary fixation versus locking plate fixation in calcaneal fractures using micro-CT image technology.

Objective: Calcaneal fracture fixation remains a challenging procedure in orthopedics, with computational tools increasingly aiding in the optimization of preoperative planning. To compare the biomechanical stability of intramedullary fixation and locking plate fixation for Sanders II and III calcaneal fractures by three-dimensional (3D) finite element analysis and to provide a theoretical basis for clinical application.

Methods: The Computed Tomography (CT) images were segmented using Mimics software (Materialise NV, Belgium) to identify the region of interest based on threshold segmentation.

[Textual research on Zitan].

In recent years, with the continuous deepening of the theory of Wu Yun Liu Qi, the application of Zitan in Shenping Decoction and Shengming Decoction has gradually become widespread. Because Zitan is an imported herbal medicine, it is not commonly used in modern medicine and known as an unusual medicinal material. The unclear original plants may affect the clinical application of this medicine.

[Prediction of anti-gastric cancer effect of Panacis Quinquefolii Radix by network pharmacology and in vivo validation].

This study investigated the anti-gastric cancer activity and mechanism of Panacis Quinquefolii Radix(Panax quinquefolium L.), and preliminarily compared the in vivo anti-gastric cancer efficacy of American-imported(JK-AG) and domestically produced(Shandong) Panacis Quinquefolii Radix decoctions(SD-AG). Based on network pharmacology predictions, a LUC-MGC803 cell ectopic gastric cancer nude mouse model was established.

Using three-dimensional virtual imaging of renal masses to improve prediction of robotic-assisted partial nephrectomy Tetrafecta with SPARE score.

Objective: To improve the predictability of outcomes in robotic-assisted partial nephrectomy, we utilized three-dimensional virtual imaging for SPARE nephrometry scoring. We compared this method with a conventional two-dimensional scoring system to determine whether 3D virtual images offer enhanced predictive accuracy for Tetrafecta outcomes.

Methods: We retrospectively collected basic information, demographic data, and perioperative indices from patients who underwent robot-assisted partial nephrectomy for renal masses at the Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University.

Signal detection and analysis of adverse events associated with Genvoya based the FAERS database.

Objective: This study aims to evaluate and understand the safety profile of Genvoya by mining and analyzing adverse drug event (ADE, adverse drug event) reports from the FDA Adverse Event Reporting System (FAERS, FDA Adverse Event Reporting System) database, thus providing valuable reference information for individuals infected with HIV.

Methods: Data were obtained from the FAERS database, covering the period from the first quarter of 2015 to the fourth quarter of 2023, focusing on reports where Genvoya was the primary suspected drug. Data import and extraction were conducted using MySQL 8.

New insights into the role of mitophagy related gene affecting the metastasis of osteosarcoma through scRNA-seq and CRISPR-Cas9 genome editing.

Background: Osteosarcoma (OSA), the most common primary bone malignancy, poses significant challenges due to its aggressive nature and propensity for metastasis, especially in adolescents. Mitophagy analysis can help identify new therapeutic targets and combined treatment strategies.

Methods: This study integrates single-cell sequencing (scRNA-seq) data and bulk-seq to identify mitophagy-related genes (MRGs) associated with the progression of OSA metastasis and analyze their clinical significance.

Prioritizing vaccine introduction to China's National Immunization Program: a multi-criteria decision analysis.

Background: To prioritize the introducing of new vaccines into China's National Immunization Program (NIP) among 10 candidate vaccines across four classes.

Methods: We developed a vaccine value framework using Multi-Criteria Decision Analysis (MCDA) to simulate the introduction of new vaccines into NIP, covering 21 criteria encompassing six dimensions: safety, effectiveness, economy, innovation, accessibility, and appropriateness. Two decision scenarios were considered: Scenario One prioritized the four classes of vaccines, while Scenario Two identified specific vaccines within each class.

An inter-regional input-output table series of China from 1987-2017 with integrated carbon emission data.

Inter-regional input-output (IRIO) tables are essential for socioeconomic and environmental analysis. This paper compiled a continuous time series of Chinese IRIO tables with a detailed regional and sectoral classification, covering a longer period from 1987 to 2017 than existing Chinese IRIO tables. Additionally, we integrated the China provincial CO emission inventory data (1987-2017) to analyze trends and identify the main driving factors behind regional economic linkages and carbon emissions changes.

The influence of multicultural experience on attitudes towards new foods in the U.S.

Many people are resuming overseas sojourns for tourism, studying abroad, and emigration to foreign countries, contributing to the increasingly diverse population in the United States. Thanks to the growing ethnic and racial diversity, American consumers can access global cuisine and are exposed to different cultures and media influences. Previous studies have highlighted the significance of comprehending the cultures of ethnic minorities and their cultural dimensions in the context of marketing context.

Evolution of two metabolic genes involved in nucleotide and amino acid metabolism in Pseudomonas aeruginosa.

Pseudomonas aeruginosa is an opportunistic human pathogen causing various severe infections. Understanding genetic mechanisms of its metabolic versatility aids in developing novel antibacterial drugs and therapeutic strategies to address multidrug-resistant P. aeruginosa infections.

Efficacy and dispensing patterns of TCM-acupuncture combinations in vascular dementia treatment: a meta-analysis and data mining analysis.

Objectives: To evaluate the clinical efficacy of the combination of acupuncture and medicine for vascular dementia (VD) treatment, and to analyze and summarize the relevant association rules.

Methods: A systematic search of Chinese and English databases such as CNKI, VIP, Wanfang, Embase, PubMed, Cochrane Library, and Web of Science was performed along with a manual search to screen for randomized controlled trials that met the inclusion and exclusion criteria that were published over a period from January 1, 2000, to July 31, 2023. Literature quality assessment and meta-analysis were performed using the and RevMan 5.

Application of CT images for reconstruction of adigital model of the sacral nerve canal.

Objectives: To construct a three-dimensional visualized model of the sacral nerve canal, and understand its structure and angles.

Methods: This was a retrospective study including 20 patients undergoing computerized tomography (CT) scanning of the sacrum. Consecutive CT images in Dicom format were directly imported into Mimics software.

Development and Application of a Quantitative Model for Proximate and Ultimate Analysis of Flue-Cured Tobacco Based on Near-Infrared Spectroscopy.

A methodology for predicting proximate and ultimate analysis data was developed by using near-infrared spectroscopy (NIR) combined with chemometric methods. The quantitative model has high accuracy, as evidenced by low root-mean-square-error of prediction (RMSEP) values (e.g.

Metaxin-2 tunes mitochondrial transportation and neuronal function in Drosophila.

Metaxins are a family of evolutionarily conserved proteins that reside on the mitochondria outer membrane (MOM) and participate in the protein import into the mitochondria. Metaxin-2 (Mtx2), a member of this family, has been identified as a key component in the machinery for mitochondrial transport in both C. elegans and human neurons.

Exploration oxidative stress underlying gastroesophageal reflux disease and therapeutic targets identification: a multi-omics Mendelian randomization study.

Introduction: Gastroesophageal reflux disease (GERD) is a chronic inflammatory gastrointestinal disease, which has no thoroughly effective or safe treatment. Elevated oxidative stress is a common consequence of chronic inflammatory conditions.

Methods: We employed Summary-data based MR (SMR) analysis to assess the associations between gene molecular characteristics and GERD.

Application of next-generation sequencing in the detection of transgenic crop.

With the rapid development of transgenic technology and the increasing prevalence of genetically modified (GMO) crops, incidents such as illegal importation, environmental contamination, and safety concerns associated with GMOs have risen significantly in recent years. Consequently, there is a growing demand for more advanced methods of GMO crop detection. Traditional molecular detection techniques, which rely on nucleic acids or proteins, are becoming less effective due to the increasing complexity of GMO crop genomes.

Elevated Bile Acids Induce Circadian Rhythm Sleep Disorders in Chronic Liver Diseases.

Background & Aims: Sleep disorders (SDs) are common in chronic liver diseases (CLDs). Some SDs arise from impaired internal clock and are, hence, circadian rhythm SDs (CRSDs). Bile acids (BAs), whose levels are increased in many CLDs, reciprocally interact with circadian rhythm.

FOXO1-mediated nuclear sequestration of STAT3 and AKT1 triggers FOXO3-dependent autophagic death in hypoxic granulosa cells.

FOXO proteins, especially FOXO1 and FOXO3, are recognized for their roles in controlling apoptosis and autophagy. Both apoptosis and autophagy have been induced in granulosa cells (GCs) by hypoxic conditions in ovarian follicles; however, the exact contribution of FOXO proteins and autophagy to the regulation of GCs apoptosis under hypoxia remains unclear. In this investigation of porcine GCs, we reveal that FOXO1 promotes apoptosis in response to hypoxia through FOXO3-dependent autophagy.

Comparative evaluation of SanAgileSA01 ultrasonic scalpel and Johnson & Johnson GEN11, and HAR36 for efficacy and safety.

Background: The advent of ultrasonic scalpels has remarkably advanced minimally invasive surgery; however, the Chinese market's reliance on imports highlights the urgent need for a cost-effective, efficient, and domestically produced surgical scalpel. This study aimed to compare SanAgileSA01 with the Johnson & Johnson GEN11, and HAR36 surgical devices.

Research Design And Methods: In total, 152 participants requiring urological or general laparoscopic surgery were randomly and equally divided between the two hospitals and randomized to the test and control groups.

Assessment of Efficacy Evidence for Approvals of Novel Drugs in China Between 2018 and 2022.

After the reform of China's drug review and approval system, there has been a notable increase in the number of novel drugs approved. This cross-sectional study aimed to assess the characteristics of efficacy evidence for novel drugs approved in China. This study included 240 novel drugs approved by the NMPA for 256 indications between 2018 and 2022.

Limbic/paralimbic connection weakening in preschool autism-spectrum disorder based on diffusion basis spectrum imaging.

This study aims to investigate the value of basal ganglia and limbic/paralimbic networks alteration in identifying preschool children with ASD and normal controls using diffusion basis spectrum imaging (DBSI). DBSI data from 31 patients with ASD and 30 NC were collected in Hunan Children's Hospital. All data were imported into the post-processing server.

Species identity crisis among New World members of the genus Heliothrips (Thysanoptera: Thripidae: Panchaetothripinae).

Until mid-1990s, Heliothrips was considered a genus without major identification problems, with only H. haemorrhoidalis spread worldwide. More recently, concerns have arisen regarding misidentifications of this pest species around the world, particularly with the description of H.

Unveiling the therapeutic mechanisms of taraxasterol from dandelion in endometriosis: Network pharmacology and cellular insights.

Aims: Endometriosis is a chronic inflammatory disease. The current treatment options in clinical practice mainly include hormonal therapy and surgical intervention. However, hormonal therapy is associated with serious side effects, and surgical treatment often leads to a high recurrence rate.