Comparative evaluation of SanAgileSA01 ultrasonic scalpel and Johnson & Johnson GEN11, and HAR36 for efficacy and safety.

Background: The advent of ultrasonic scalpels has remarkably advanced minimally invasive surgery; however, the Chinese market's reliance on imports highlights the urgent need for a cost-effective, efficient, and domestically produced surgical scalpel. This study aimed to compare SanAgileSA01 with the Johnson & Johnson GEN11, and HAR36 surgical devices.

Research Design And Methods: In total, 152 participants requiring urological or general laparoscopic surgery were randomly and equally divided between the two hospitals and randomized to the test and control groups.

Assessment of Efficacy Evidence for Approvals of Novel Drugs in China Between 2018 and 2022.

After the reform of China's drug review and approval system, there has been a notable increase in the number of novel drugs approved. This cross-sectional study aimed to assess the characteristics of efficacy evidence for novel drugs approved in China. This study included 240 novel drugs approved by the NMPA for 256 indications between 2018 and 2022.

Limbic/paralimbic connection weakening in preschool autism-spectrum disorder based on diffusion basis spectrum imaging.

This study aims to investigate the value of basal ganglia and limbic/paralimbic networks alteration in identifying preschool children with ASD and normal controls using diffusion basis spectrum imaging (DBSI). DBSI data from 31 patients with ASD and 30 NC were collected in Hunan Children's Hospital. All data were imported into the post-processing server.

Species identity crisis among New World members of the genus Heliothrips (Thysanoptera: Thripidae: Panchaetothripinae).

Until mid-1990s, Heliothrips was considered a genus without major identification problems, with only H. haemorrhoidalis spread worldwide. More recently, concerns have arisen regarding misidentifications of this pest species around the world, particularly with the description of H.

Unveiling the therapeutic mechanisms of taraxasterol from dandelion in endometriosis: Network pharmacology and cellular insights.

Aims: Endometriosis is a chronic inflammatory disease. The current treatment options in clinical practice mainly include hormonal therapy and surgical intervention. However, hormonal therapy is associated with serious side effects, and surgical treatment often leads to a high recurrence rate.

First report of causing Diplodia leaf streak disease of maize in Yunnan Province, China.

Maize (Zea mays. L) is cultivated globally as a staple food crop, animal feed, and biofuel. However, persistent diseases in maize have led significant yield losses and a decline in grain quality (Yang et al.

[Laboratory malaria re-examination and evaluation of malaria diagnostic capability in Shanghai Municipal Malaria Diagnostic Reference Laboratory from 2017 to 2022].

Objective: To evaluate the malaria diagnostic capability in Shanghai Municipal Malaria Diagnostic Reference Laboratory from 2017 to 2022 and to analyze factors affecting the diagnosis results, so as to provide the scientific evidence for increasing the laboratory malaria diagnostic capability during the post-elimination stage.

Methods: -negative blood smears were randomly sampled using a proportional sampling method each quarter during the period from 2017 to 2022 and scored by Shanghai Municipal Malaria Diagnostic Reference Laboratory. Malaria cases' blood samples from district centers for disease control and prevention in Shanghai Municipality were re-reviewed using microscopy and multiplex PCR assay to evaluate the capability of malaria diagnosis.

KPNA3 regulates histone locus body formation by modulating condensation and nuclear import of NPAT.

The histone locus body (HLB) is a membraneless organelle that determines the transcription of replication-dependent histones. However, the mechanisms underlying the appropriate formation of the HLB in the nucleus but not in the cytoplasm remain unknown. HLB formation is dependent on the scaffold protein NPAT.

A newly custom coordinate system used for preoperative planning of robotic-assisted total knee arthroplasty.

Purpose: Preoperative planning is critical for total knee arthroplasty (TKA) performed with surgical robots, as it involves establishing a coordinate system to calculate the angle values of the components. This coordinate system serves as a reference during the surgical planning stage. This study aimed to develop a newly custom coordinate system suitable for integration with a surgical robot system.

Homozygous variant in translocase of outer mitochondrial membrane 7 leads to metabolic reprogramming and microcephalic osteodysplastic dwarfism with moyamoya disease.

Background: Impaired mitochondrial protein import machinery leads to phenotypically heterogeneous diseases. Here, we report a recurrent homozygous missense variant in the gene that encodes the translocase of outer mitochondrial membrane 7 (TOMM7) in nine patients with microcephaly, short stature, facial dysmorphia, atrophic macular scarring, and moyamoya disease from seven unrelated families.

Methods: To prove the causality of the TOMM7 variant, mitochondrial morphology, proteomics, and respiration were investigated in CRISPR/Cas9-edited iPSCs-derived endothelial cells.

Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism.

The CorA/Mrs2 family of pentameric proteins are cardinal for the influx of Mg across cellular membranes, importing the cation to mitochondria in eukaryotes. Yet, the conducting and regulation mechanisms of permeation remain elusive, particularly for the eukaryotic Mrs2 members. Here, we report closed and open Mrs2 cryo-electron microscopy structures, accompanied by functional characterization.

[Application of surface landmark positioning in assisting cone-beam CT scanning of temporomandibular joint].

To quantitatively measure the spatial relationship between the temporomandibular joint (TMJ) and surface landmarks such as the tragus and lateral canthus using cone-beam CT (CBCT), as to provide guidance for accurate positioning of CBCT scanning of the TMJ. DICOM format data from 112 patients (35 males and 77 females with 224 TMJs) were included in this study. The patients were between 12 and 66 years old, with a mean age of (25.

[Efficacy analysis of 3D printing prefixed nail path model assisted lumbar and sacral hemivertebra orthopaedic surgery].

Objective: To analyze the safety and effectiveness of 3D printing prefabricated nail path model assisted lumbosacral hemivertebra orthopaedic surgery.

Methods: A retrospective analysis was performed on 8 patients with lumbosacral hemivertebra deformity admitted from January 2016 to July 2021, including 3 males and 5 females, aged 6 to 15 at the time of surgery. The hemivertebra of 4 cases located on the left side and 4 cases on the right side.

[Comparison of the stability of dual INFIX and INFIX combined with sacroiliac screw fixation for C1 type pelvic fractures].

Objective: To evaluate the biomechanical stability of dual anterior subcutaneous internal fixation (INFIX) in pelvic C1 fractures by finite element analysis, and to compare it with INFIX combined with sacroiliac screws to determine whether it is sufficient to replace the combined fixation of anterior and posterior rings.

Methods: The pelvic CT data of a 43-year-old female volunteer were imported into the computer and the normal pelvic model and pelvic C1 fractures model were constructed using Mimics, Workbench and other software. The latter was fixed with dual INFIX and INFIX combined with sacroiliac screws, respectively.

Regulatory issues related to the use of sodium hypochlorite solutions in endodontics.

Aim: To assess the regulation of sodium hypochlorite (NaOCl) solutions for endodontic usage in some of the world's main dental markets, in view of the European Union's recent move to classify antimicrobial root canal irrigants as high-risk devices under their Medical Device Regulation (MDR).

Methodology: The authors consulted legal texts available online and communicated with local health authorities wherever necessary to assess into which medical device category NaOCl solutions intended for endodontic application were subsumed. Furthermore, it was investigated whether there were sources outside the dental market to obtain NaOCl solutions for root canal treatments.

Comparative Analysis of PGRP Family in Polymorphic Worker Castes of .

Peptidoglycan recognition proteins (PGRPs) are a class of pattern recognition receptors (PRRs) that activate the innate immune system in response to microbial infection by detection of peptidoglycan, a distinct component of bacterial cell walls. Bioinformatic studies have revealed four PGRPs in the red imported fire ant ; nonetheless, the mechanism of the immune response of induced by pathogens is still poorly understood. The peptidoglycan recognition protein full-length cDNA (designated as -) from was used in this investigation.

Nutrient Content Prediction and Geographical Origin Identification of Bananas by Combining Hyperspectral Imaging with Chemometrics.

The nutritional quality of bananas and their geographical origin authenticity are very important for trade. There is an urgent need for rapid, non-destructive testing to improve the origin and quality assurance for importers, distributors, and consumers. In this study, 99 banana samples from a range of producing countries were collected.

Global Traction Battery Cathode Material Industrial Chain Trade Analysis: A Multilayer Modeling Approach.

The fast expansion of the electric vehicle market has led to a significant increase in the demand for traction batteries, an essential element in these vehicles that provide the opportunity to achieve low-carbon and environmentally friendly growth and carbon neutrality. By analyzing the network structure and key trading countries from 2000 to 2021, this research uses multilayer network theory to explore the trade patterns and the evolution of the global cathode material industrial chain of traction batteries. Our findings indicate the following: (1) The industrial networks display multi-core trading country characteristics.