950 results match your criteria: "China Guangxi Institute of Traditional Chinese Medicine & Pharmaceutical Science Nanning China.[Affiliation]"
Int J Biol Macromol
January 2025
School of Chemistry and Chemical Engineering, Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, Nanning 530006, China. Electronic address:
Limitations of the blood-brain barrier (BBB) are responsible for the low efficacy and high toxicity of many antidepressants. However, strategies to enhance BBB targeting to improve the efficacy and safety of antidepressants remain challenging. In this study, we prepared transferrin (Tf)-functionalized chitosan (CS)-N,O-carboxymethy chitosan (NOCMS) nanosystems (NPs) (NOCMS-CS-Tf NPs), which can enhance BBB targeting in the depressive environment and allow more NPs to enter the brain.
View Article and Find Full Text PDFEur J Med Chem
February 2025
Institute of Traditional Chinese and Zhuang-Yao Ethnic Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guang Xi Zhuang Yao Medicine Center of Engineering and Technology, Wuhe Rode, Nanning, 530200, China. Electronic address:
Cutan Ocul Toxicol
December 2024
Guangdong Provincial Center for Ophthalmic Drug Creation and Evaluation Engineering Technology, Guangzhou Bay Area Institute of Biomedicine, Guangdong Lewwin Pharmaceutical Research Institute Co., Ltd., Guangdong Provincial Key Laboratory of Drug Non-Clinical Evaluation and Research, TCM Non-clinic Evaluation Branch of National Engineering Research Center for Modernization of Traditional Chinese Medicine, Guangdong, China.
Objectives: This study was to investigate the effects of atropine sulphate eye drops (ASED)on the development of partial systems in young rats and their toxic reactions following repeated eye-drop administration over a period of 40 days.
Methods: SD rats of 20 days old were randomly assigned to control group, 0.01, 0.
iScience
November 2024
Department of Spinal Surgery, Guangxi Medical University Affiliated Liuzhou People's Hospital, Liuzhou, China.
Ecol Evol
December 2024
Guangxi Key Laboratory of Plant Conservation and Restoration Ecology in Karst Terrain Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences Guilin Guangxi China.
The genus is renowned for its remarkably diverse floral morphology, exhibiting a high level of disparity compared to most genera within Gesneriaceae. In this study, we present a detailed description and illustration of T. Ding & B.
View Article and Find Full Text PDFGenes (Basel)
November 2024
College of Computer, National University of Defense Technology, Changsha 410073, China.
Background: Lour., a genus in the subfamily Cercidoideae of the family Leguminosae, is characterized by woody liana habit, tendrils, and distinctive bilobate or bifoliolate leaves. The genus holds important medicinal value and constitutes a complex group characterized by morphological diversity and unstable taxonomic boundaries.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
February 2025
Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine.
Background: Alcohol is linked to various cancers. While many studies have focused on developed countries, the burden of alcohol-related cancers in developing countries remains underexplored.
Methods: We analyzed data from the Global Burden of Disease Study (2000-2019) to assess mortality and disability-adjusted life years (DALYs) from alcohol-related cancers in low and low-to-middle sociodemographic index (SDI) countries.
Glob Med Genet
December 2024
Department of Respiratory Medicine, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, People's Republic of China.
Phytomedicine
November 2024
Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, PR China. Electronic address:
Background: YOXINTINE contains >98 % of 20(S)-protopanaxadial (PPD), a metabolic product of ginsenosides with pre-clinical neuroprotective activity. Animal experiments and previous studies have shown that PPD has good antidepressant effect and safety.
Purpose: To evaluate YOXINTINE in treating depression compared with a placebo in Chinese patients.
BMC Cardiovasc Disord
November 2024
Guangxi University of Chinese Medicine, Nanning, 530000, China.
Background: Electrolyte imbalances are commonly observed in individuals diagnosed with myocardial infarction (MI). The levels of serum sodium have been linked to unfavorable outcomes in relation to MI. Additionally, there exists a correlation between serum sodium and serum chloride, although the combined influence of these electrolytes on the prognosis of MI patients has not been extensively studied.
View Article and Find Full Text PDFFront Immunol
November 2024
Department of Rheumatology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Hematology
December 2024
Department of Medical Oncology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guangxi, People's Republic of China.
Background: The application of traditional Chinese medicine (TCM) therapy to acute leukemia has been intensively investigated. However, the bibliometric analysis in this field has not been performed. This bibliometric study aimed to comprehensively analyze the research trends and active areas of TCM therapy for acute leukemia from 2000 to 2023.
View Article and Find Full Text PDFInnovation (Camb)
November 2024
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Melanoma and Sarcoma, Peking University Cancer Hospital & Institute, Beijing 100142, P.R. China.
Sci Rep
November 2024
Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cardiovascular Disease, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Transthoracic echocardiography (TTE) is widely recognized as one of the principal modalities for diagnosing tricuspid regurgitation (TR). The diagnostic procedures associated with conventional methods are intricate and labor-intensive, with human errors leading to measurement variability, with outcomes critically dependent on the operators' diagnostic expertise. In this study, we present an innovative assessment methodology for evaluating TR severity utilizing an end-to-end deep learning system.
View Article and Find Full Text PDFNutr Rev
November 2024
Institute of Translational Medicine, School of Medicine, Yangzhou University, Yangzhou, Jiangsu Province 225009, China.
The natural polyphenol resveratrol (RV) has garnered fame for its extensive pharmacological properties. Although clinical studies have shown some positive results, many contradictory outcomes remain. An important obstacle to the development of therapeutic applications for RV is its low bioavailability in vivo.
View Article and Find Full Text PDFNat Commun
November 2024
Department of Resources Science of Traditional Chinese Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, 211198, Nanjing, China.
Asparagales, the largest monocot order, is renowned for its ecological, economic, and medicinal significance. Here, we leverage transcriptome data from 455 Asparagales species to explore the phylogeny of Asparagales. Moreover, we investigate the evolutionary patterns of the genes involved in allium flavor formation.
View Article and Find Full Text PDFJ Control Release
December 2024
State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China. Electronic address:
Brain diseases are a significant threat to human health, especially in the elderly, and this problem is growing as the aging population increases. Efficient brain-targeted drug delivery has been the greatest challenge in treating brain disorders due to the unique immune environment of the brain, including the blood-brain barrier (BBB). Recently, cerebral biomimetic nano-drug delivery systems (CBNDSs) have provided a promising strategy for brain targeting by mimicking natural biological materials.
View Article and Find Full Text PDFRisk Manag Healthc Policy
October 2024
Nursing Department, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.
Objective: To investigate the current status of elderly health services in medical institutions at all levels within Guangxi Province, China.
Methods: Using a purposeful sampling method, a questionnaire survey was conducted from July 24, 2023 to October 24, 2023 on the general situation, human resources, rehabilitation medicine, nursing services, and the development of hospice care at 1305 medical institutions in Guangxi.
Results: Among the surveyed 1305 medical institutions in Guangxi, 172 (13.
Biosens Bioelectron
January 2025
Taizhou Key Laboratory of Medical Devices and Advanced Materials, Research Institute of Zhejiang University, Taizhou, 318000, PR China; Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, PR China. Electronic address:
Chronic wounds cause serious health and economic burdens on patients and society. Herein, a wireless and flexible smart wound dressing was developed for matrix metalloproteinase-9 (MMP-9) monitoring and antimicrobial treatment toward chronic wound management. The highly sensitive radio frequency MMP-9 sensor was realized based on a bioresponsive hydrogel with the bioactive peptide sequences.
View Article and Find Full Text PDFAnn Anat
January 2025
Key Laboratory of Molecular Pathology in Tumors of GuangxiHigher Education Institutions, Baise, Guangxi 533000, PR China; Neurosurgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, PR China. Electronic address:
Bioorg Chem
December 2024
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address:
An exploration of antibacterial components from the whole plant of Euphorbia humifusa led to the isolation of 14 new triterpenoids, euphohumifusoids A-N (1-7 and 9-15), as well as four known analogues (8 and 16-18). Their structures were elucidated by extensively analysis of the spectroscopic data and X-ray crystallography using Cu Kα radiation. Among them, euphohumifusoid A (1) bears an unique 6(7 → 8)abeo scaffold originated from a D:C-friedo-oleanane skeleton for the first time, euphohumifusoids H and I (9 and 10) possess a rare α,β-unsaturated-γ-lactone chain originated from 25,26,27-trinordammaranes, and euphohumifusoid L (13) is a highly modified 3,4-seco-25,26,27-trinorcycloartane.
View Article and Find Full Text PDFPhytomedicine
December 2024
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-products Processing, Ministry of Agriculture and Rural Affairs, Beijing 100193, China. Electronic address:
Background: Our previous study found that the polysaccharide from Laoxianghuang (LP), fermented fruit of bergamot (traditional Chinese medicine and food), can alter gut microbiota and regulate short-chain fatty acids (SCFAs) in vitro. Nevertheless, there is a paucity of reports on the impact of LP on gut microbiota in vivo.
Purpose: To analyze the structures of LP, investigate the influence of LP on the damaged intestinal barrier in DSS-induced colitis mice, and further explore its potential mechanisms.
Cancer Rep (Hoboken)
October 2024
Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Research Center of Traditional Chinese Medicine and Ethnic Medicine, Guangxi Institute of Chinese Medicine and Pharmaceutical Science, Nanning, China.
Objectives: Glioblastoma multiforme (GBM) is considered the most assailant subtype of gliomas, presenting a formidable obstacle because of its inherent resistance to temozolomide (TMZ). This study aimed to characterize the function of lncRNA NEAT1 in facilitating the advancement of gliomas.
Methods: The expression level of NEAT1 in glioma tissues and cells was detected by qRT-PCR.
Pharmacol Res
November 2024
School of Biomedical Sciences, University of Western Australia, Perth, Western Australia 6009, Australia. Electronic address:
PhytoKeys
October 2024
College of Forestry, Central South University of Forestry and Technology, Changsha, Hunan, China Central South University of Forestry and Technology Changsha China.
Y.Nong & L.Wu (Rubiaceae), a new species from Guangxi, China, is described and illustrated.
View Article and Find Full Text PDF