7 results match your criteria: "China Experimental Research Center[Affiliation]"

[Main nutrients content in different specifications of Gastrodiae Rhizoma].

Zhongguo Zhong Yao Za Zhi

September 2024

Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, School of Pharmacy, Hebei University of Chinese Medicine Shijiazhuang 050200, China Experimental Research Center, China Academy of Chinese Medical Sciences Beijing 100700, China.

Gastrodiae Rhizoma is a valuable traditional Chinese medicine(TCM) and was newly approved as a catalogue species of medicinal and food homologous substances in 2023. The consumption of Gastrodiae Rhizoma as a food has been increasing year by year, and its nutrients content has become a public concern. However, there is a lack of systematic research on its nutrients content.

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[Establishment and optimization of Agrobacterium tumefaciens-mediated genetic transformation system for Polyporus umbellatus].

Zhongguo Zhong Yao Za Zhi

August 2024

School of Pharmacy, Shaanxi University of Chinese Medicine Xianyang 712046, China Experimental Research Center,China Academy of Chinese Medical Sciences Beijing 100700, China.

The unstable quality of Polyporus umbellatus sclerotia during cultivation is the key factor affecting the quality and yield of P. umbellatus sclerotia. In order to provide technical support for obtaining superior P.

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[Influence of Tis108 on GA content and expression of key enzyme GeCYP714A1 involved in GA deactivation of Gastrodia elata].

Zhongguo Zhong Yao Za Zhi

August 2024

College of Pharmacy, Shaanxi University of Chinese Medicine Xianyang 712000, China Experimental Research Center,China Academy of Chinese Medical Sciences Beijing 100700, China.

Article Synopsis
  • This study explored how the strigolactone inhibitor Tis108 affects the growth of the plant Gastrodia elata by treating its tubers with a Tis108 solution and measuring gibberellin (GA) levels.
  • It was found that Tis108 treatment significantly increased GA content while decreasing the expression of the GeCYP714A1 gene, which is involved in GA deactivation.
  • Bioinformatics analysis revealed that GeCYP714A1 encodes a protein that has a close relationship with a similar protein from Dendrobium candidum, suggesting its important role in the regulation of GA and tuber development in G. elata.
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[Establishment and application of quality evaluation method for Xiaochaihu Granules based on calibrator samples].

Zhongguo Zhong Yao Za Zhi

January 2022

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China Experimental Research Center, China Academy of Chinese Medical Sciences Beijing 100700, China.

With reference to the production process documented in Chinese Pharmacopoeia, this paper prepared the calibrator samples of Xiaochaihu Granules from multiple batches and established a method for fingerprint analysis and content determination that could be used to evaluate Xiaochaihu Granules available in market. Multiple batches of Chinese herbal pieces contained in Xiaochaihu Granules were collected for preparing the calibrator samples according to the process in Chinese Pharmacopoeia. Following the establishment of fingerprints for calibrator samples by UHPLC, the method for determining the contents of saikosaponin B2, saikosaponin B1, baicalin, wogonoside, baicalein, liquiritin, glycyrrhizin G2 and glycyrrhizic acid in Xiaochaihu Granules was established.

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To investigate the effects of SPAG6 silencing and decitabine on apoptosis and phosphatase and tensin homolog (PTEN) methylation in SKM-1 cells in vitro and in vivo. SKM-1 cells were transfected with a lentiviral vector to silence the expression of SPAG6. Cell survival rate was detected by CCK8 after treatment with decitabine, and cell apoptosis was detected by flow cytometry.

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To systematically review the effectiveness and safety of Reduning Injection in the treatment of acute tracheal-bronchitis.Four Chinese databases( CNKI,VIP,Wan Fang,Sino Med) and three English databases( Cochrane Library,Medline,Web of Science) were systematically and comprehensively retrieved. The retrieval time was from the establishment of each database to April 2019.

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Guizhi decoction (GZD), a well-known traditional Chinese medicine (TCM) prescription consisting of Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, Fructus Jujubae and Rhizoma Zingiberis Recens, is usually used for the treatment of common colds, influenza, and other pyretic conditions in the clinic. However, the absorbed ingredients and metabolic compounds of GZD have not been reported. In this paper, a method incorporating rapid resolution liquid chromatography (RRLC) with quadrupole-time-of-flight mass spectrometry (Q-TOF-MS) was used to identify ingredients after oral administration of GZD.

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