SnHPO: A Layered Tin(II) Phosphate with Enhanced Birefringence.

As promising optoelectronic functional materials in the short-wavelength spectral region, such as ultraviolet (UV) and deep UV, phosphates have recently received increased attention. However, phosphate materials commonly suffer from limited birefringence owing to the highly symmetrical PO tetrahedra. We herein report a layered tin(II) phosphate with improved birefringence.

Highly Sensitive Digital and Analog Immunoassay Based on Submicron Magnetic Beads and Fluorescent Microspheres.

The detection of disease-related protein biomarkers plays a crucial role in the early diagnosis, treatment, and monitoring of diseases. The concentrations of protein biomarkers can vary significantly in different diseases or stages of the same disease. However, most of the existing analytical methods cannot simultaneously meet the requirements of high sensitivity and a wide dynamic range.

Key glycometabolism during oocyte maturation and early embryonic development.

In recent decades, it has become increasingly clear that mammalian gametes and early embryos are highly sensitive to metabolic substrates. With advances in single-cell sequencing, metabolomics, and bioinformatics, we now recognize that metabolic pathways not only meet cellular energy demands but also play a critical role in cell proliferation, differentiation, and fate determination. Investigating metabolic processes during oocyte maturation and early embryonic development is thus essential to advancing reproductive medicine and embryology.

Comparison of Short-term Outcomes Following Minimally Invasive (Endoscopic/Robotic) vs Open Thyroidectomy for Patients With Thyroid Cancer.

Background Selection between open thyroidectomy (OT) and minimally invasive (endoscopic/robotic) thyroidectomy (MT) for patients with thyroid cancer has been a subject of considerable debate. Comprehensive analysis of the short-term outcomes of endoscopic thyroidectomy (ET), robotic thyroidectomy (RT) and OT for thyroid cancer using a large-scale dataset is important. Methods This cohort study evaluated the outcomes of patients receiving ET, RT vs OT for thyroid cancer from January 1, 2003, to December 31, 2022.

EXO: A Dual-Mechanism Stimulator of Interferon Genes Activator for Cancer Immunotherapy.

As natural agonists of the stimulator of interferon genes (STING) protein, cyclic dinucleotides (CDNs) can activate the STING pathway, leading to the expression of type I interferons and various cytokines. Efficient activation of the STING pathway in antigen-presenting cells (APCs) and tumor cells is crucial for antitumor immune response. Tumor-derived exosomes can be effectively internalized by APCs and tumor cells and have excellent potential to deliver CDNs to the cytoplasm of APCs and tumor cells.

The Effect of Nurse-led Preoperative Visits on Anxiety: An Integrative Review.

Purpose: This review aims to investigate the effectiveness of nurse-led preoperative visits for the reduction of presurgical anxiety. The review will explore the patterns and mechanisms through which these visits alleviate anxiety, identify the existing practice gaps, and suggest future directions for improvement. The findings will help health care providers choose appropriate visits for their patients.

The Effect of Music Combined With Preoperative Education on Perioperative Anxiety in Patients Undergoing Open Cardiac Surgery: A Randomized Controlled Trial.

Purpose: The aim of this study is to observe the effect of music combined with preoperative education on perioperative anxiety in patients undergoing open cardiac surgery.

Design: This was a randomized controlled study.

Methods: A group of 322 patients undergoing elective open cardiac surgery were randomly allocated to receive either music combined with preoperative education (the experimental group) or routine preoperative preparation (the control group).

Spinal Epidural Hematoma Following Combined Spinal Epidural Anesthesia: A Case Report.

A spinal epidural hematoma (SEH) is a rare complication of combined spinal epidural anesthesia. The case of a 55-year-old man who underwent orthopedic surgery under combined spinal epidural anesthesia is presented. Flurbiprofen and horse chestnut seed extract that potentially affect coagulation function during the perioperative period were used.

Associations of Short-Term Ozone Exposure With Hypoxia and Arterial Stiffness.

Background: Epidemiological studies reported associations between ozone (O) exposure and cardiovascular diseases, yet the biological mechanisms remain underexplored. Hypoxia is a shared pathogenesis of O-associated diseases; therefore, we hypothesized that O exposure may induce changes in hypoxia-related markers, leading to adverse cardiovascular effects.

Objectives: This study aimed to investigate associations of short-term O exposure with hypoxic biomarkers and arterial stiffness.

Cardiovascular Disease-Specific Responses to Autonomic Denervation.

Background: Calcium-mediated autonomic denervation has been shown to suppress postoperative atrial fibrillation (POAF) after coronary artery bypass grafting.

Objectives: This study sought to evaluate whether similar autonomic denervation can prevent POAF after mitral or aortic valve surgeries.

Methods: This research consisted of 2 single-center, randomized, double-blind, sham-controlled trials: CAP-AF2 (Calcium Autonomic Denervation Prevents Postoperative Atrial Fibrillation in Patients Undergoing Isolated Mitral Valve Surgery for Mitral Regurgitation) for mitral valve (MV) surgery and CAP-AF3 (Calcium Autonomic Denervation Prevents Postoperative Atrial Fibrillation in Patients Undergoing Isolated Aortic Valve Surgery) for aortic valve surgery.

-Ge/B 1,1-Hydroboration of Alkynylgermanes with 9-BBN.

A 1,1-hydroboration of alkynylgermanes with unique -Ge/B stereochemistry under transition-metal-free conditions is reported. Mechanistic studies suggest that a pathway involving α-boration followed by a stepwise 1,2-Ge/H shift on the intermediate structurally lies between an alkyne-Ge π complex and a typical vinyl cation. The resulting Ge/B bimetallic modules, along with a /Ge/B trimetallic variant, can be conveniently transformed into trisubstituted olefins through iterative divergent cross-coupling.

Integration of Asymmetric Multi-Path Hollow Structure and Multiple Heterogeneous Interfaces in FeO@C@NiO Nanoprisms Enabling Ultra-Low and Broadband Absorption.

A reasonable construction of hollow structures to obtain high-performance absorbers is widely studied, but it is still a challenge to select suitable materials to improve the low-frequency attenuation performance. Here, the FeO@C@NiO nanoprisms with unique tip shapes, asymmetric multi-path hollow cavity, and core-shell heteroepitaxy structure are designed and synthesized based on anisotropy and intrinsic physical characteristics. Impressively, by changing the load of NiO, the composites achieve strong absorption, broadband, low-frequency absorption: the reflection loss of -55.

Photocatalytic Three-Component Reductive Coupling Synthesis of -Difluorohomoallyl Secondary Amines.

-Difluorohomoallyl amines, an important class of -difluoroalkenes, are prevalent moieties in many bioactive compounds. However, limited methods are suitable for the synthesis of this type of compound containing secondary amines. Here, we display a photocatalytic multicomponent protocol for the synthesis of -difluoroalkenes containing secondary amines, which makes use of readily available materials: arylamines, alkyl aldehydes, and α-trifluoromethyl alkenes.

Bio-Inspired Highly Stretchable and Ultrafast Autonomous Self-Healing Supramolecular Hydrogel for Multifunctional Durable Self-Powered Wearable Devices.

As skin bioelectronics advances, hydrogel wearable devices have broadened perspectives in environment sensing and health monitoring. However, their application is severely hampered by poor mechanical and self-healing properties, environmental sensitivity, and limited sensory functions. Herein, inspired by the hierarchical structure and unique cross-linking mechanism of hagfish slime, a self-powered supramolecular hydrogel is hereby reported, featuring high stretchability (>2800% strain), ultrafast autonomous self-healing capabilities (electrical healing time: 0.

Hydrogen-Bonding-Driven Design of Organic-Inorganic Hybrid Ferroelastics with Reversible Photoisomerization.

The development of photoresponsive ferroelastics, which couple light-induced macroscopic mechanical and microscopic domain properties, represents a frontier in materials science with profound implications for advanced functional applications. In this study, we report the rational design and synthesis of two new organic-inorganic hybrid ferroelastic crystals, (MA)(MeN)[Fe(CN)(NO)] (MA = methylammonium) () and (MA)(MeNOH)[Fe(CN)(NO)] (), using a dual-organic molecular design strategy that exploits hydrogen-bonding interactions for tailoring ferroelastic properties. Specifically, exhibits a two-step phase transition at 138 and 242 K, while the introduction of a hydroxyl group in stabilizes its ferroelastic phase to a significantly higher temperature, achieving a phase transition at 328 K, 86 K above that of .

Protective association between dietary phytosterol intake and cardiovascular health: an analysis of the UK Biobank cohort.

: Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality worldwide, with dietary interventions showing promise in reducing CVD risk factors. Phytosterols (PSs) in plant-based foods may reduce CVD risk by lowering low-density lipoprotein cholesterol. However, the relationship between dietary PS intake and CVD outcomes remains inconclusive.

Engineering ZIF-8@Ag core-satellite superstructures through solvent-induced tunable self-assembly for surface-enhanced Raman spectroscopy.

Metal-organic framework (MOF) based substrates have great potential for quantitative analysis of hazardous substances using surface-enhanced Raman spectroscopy (SERS) due to their significant signal enhancement, but face challenges like complex preparation, and lack of tunability. Here, we have successfully prepared a well-defined core-satellite superstructure (ZIF-8@Ag) through solvent-induced assembly of silver nanoparticles (Ag NPs) on truncated rhombic dodecahedral ZIF-8. By wisely selecting toluene as the solvent, the assembly process can be easily initiated through ultrasonic treatment and it allows for precise morphological adjustments to build a range of superstructures with different assembly densities of Ag NPs feed ratio tuning.

The impact of remimazolam compared to propofol on postoperative delirium: a systematic review and meta-analysis.

Introduction: The administration of benzodiazepines has been linked to the occurrence of postoperative delirium (POD) among patients undergoing surgery. In this review, we aim to appraise the current controversy regarding the role of remimazolam in POD.

Evidence Acquisition: A systematic review and meta-analysis of randomized controlled trials was conducted to examine the effects of remimazolam administration on postoperative delirium compared to propofol from inception to April 2024.

Enhanced Mechanical Properties in Bulk Nanograined Ni with High-Density Fivefold Twins.

Fivefold twins are extensively present in nanoparticles and nanowires, enhancing their performance in physical, chemical, and mechanical properties. However, a deep insight into the correlation between mechanical properties and fivefold twins in bulk nanograined materials is lacking due to synthesis difficulties. Here, a bulk fivefold-twinned nanograined Ni is synthesized via electrodeposition.

Ni Single Atoms/FeN Nanoparticles Supported by N-Doped Carbon Hollow Nanododecahedras with Nanotubes on the Surface for Efficient Electro-Reduction of CO to CO.

The transition metal single atoms (SAs)-based catalysts with M-N coordination environment have shown excellent performance in electrocatalytic reduction of CO, and they have received extensive attention in recent years. However, the presence of SAs makes it very difficult to efficiently improve the coordination environment. In this paper, a method of direct high-temperature pyrolysis carbonization of ZIF-8 adsorbed with Ni and Fe ions is reported for the synthesis of Ni SAs and FeN nanoparticles (NPs) supported by the N-doped carbon (NC) hollow nanododecahedras (HNDs) with nanotubes (NTs) on the surface (Ni SAs/FeN NPs@NC-HNDs-NTs).

Automatic visual detection of activated sludge microorganisms based on microscopic phase contrast image optimisation and deep learning.

The types and quantities of microorganisms in activated sludge are directly related to the stability and efficiency of sewage treatment systems. This paper proposes a sludge microorganism detection method based on microscopic phase contrast image optimisation and deep learning. Firstly, a dataset containing eight types of microorganisms is constructed, and an augmentation strategy based on single and multisamples processing is designed to address the issues of sample deficiency and uneven distribution.

Effects of an electrospun Janus structure on enhanced UV resistance performance.

Thermoplastic polyurethane (TPU) fabrics often possess good mechanical, waterproofing, and breathability properties. However, the resistance of TPU to excessive ultraviolet (UV) irradiation is poor and often does not meet the UV resistance requirements of fabrics. Electrospun nanofibers with a side-by-side structure can combine the advantages of different materials.

Value of Noncontrast-Enhanced Vessel Wall MRI in Longitudinal Venous System Invasion Before Robot-Assisted Radical Nephrectomy.

To explore the value of vessel wall MRI (VW-MRI) in the preoperative assessment of T3 renal-cell carcinoma (RCC) with varying degrees of longitudinal venous system invasion. Patients with RCC with pathological T3 stage between January 2016 and December 2023 were included in this retrospective study. All the patients underwent contrast-enhanced CT (CECT), conventional MRI (con-MRI) or VW-MRI.

FEMC-deuterogenic artificial solid electrolyte interphase boosts high-performance sodium-ion batteries.

A NaF-rich composite artificial interphase is generated relying on a simple chemical reaction by regulating methyl 2,2,2-trifluoromethyl ester reactivity, which can promote rapid ion transport and effectively inhibit dendrite growth in carbonate electrolytes. The assembled NaF@Na‖NaV(PO) full cell attains a long lifespan of 4000 cycles at 5C with 95% capacity retention, and a high specific capacity of 80.8 mAh g at 30C.