Confining Spirocyclic Fluorescein in an Asymmetric Solid-State Nanochannel: A Simple and Versatile Design Concept for Fabricating Integrated Nanofluidic Diodes with Adjustable Surface Chemistry.

Using small molecules to integrate multifunctional surfaces within a nanopore is an effective way to endow smart responsibilities of nanofluidic diodes. However, the complex synthesis of the small molecules hinders their further application in achieving multifunctional surfaces. Here, a simple and versatile design concept is reported for fabricating bioinspired integrated nanofluidic diodes with adjustable surface chemistry by confining a spirocyclic fluorescein derivative, 6-aminofluorescein (6-AF), within an asymmetric track-etched nanopore.

Manipulation of Single Nanowire and its Applications.

Micro/nano manipulation of single nanowire has emerged as a popular direction of study in the field of nanotechnology, with promising applications in cutting-edge technologies such as device manufacturing, medical treatment, and nanorobotics. The synthesis of nanowires with controllable length and diameter makes them meet various micro/nano manipulation demands. As manipulation techniques have advanced, including the use of optical tweezers, electric and magnetic fields, mechanical control, and several more control methods, they have demonstrated unique advantages in different application fields.

Advances in Polymer-Based Self-Adjuvanted Nanovaccines.

Nanovaccines, as a new generation of vaccines, have garnered significant interest due to their exceptional potential in enhancing disease prevention and treatment. Their unique features, such as high stability, antigens protection, prolonged retention, and targeted delivery to lymph nodes, immune cells, and tumors, set them apart as promising candidates in the field of immunotherapy. Polymers, with their superior degradability, capacity to mimic pathogen characteristics, and surface functionality that facilitates modifications, serve as ideal carriers for vaccine components.

Layered-Hierarchical Dual-Lattice Strain Suppresses NiSe Surface Reconstruction for Stable OER in Alkaline Fresh/Seawater Splitting.

Transition metal selenides (TMSe) are promising oxygen evolution reaction (OER) electrocatalysts but act as precursors rather than the actual active phase, transforming into amorphous oxyhydroxides during OER. This transformation, along with the formation of selenium oxyanions and unstable heterointerfaces, complicates the structure-activity relationship and reduces stability. This work introduces novel "layered-hierarchical dual lattice strain engineering" to inhibit the surface reconstruction of NiSe by modulating both the nickel foam (NF) substrate with MoN nanosheets (NM) and the NiSe nanorods-nanosheets catalytic layer (NiSe-NiSe-NiO, NSN) with ultrafast interfacial bimetallic amorphous NiFeOOH coating, achieving the optimized NM/NSN/NiFeOOH configuration.

Recent Advances for Cation-Anion Aggregates in Solid Polymer Electrolytes: Mechanism, Strategies, and Applications.

Solid polymer electrolytes (SPEs) have garnered significant attention from both academic and industrial communities due to their high safety feature and high energy density in combination with lithium(Li) metal anode. Nevertheless, their practical applications remain constrained by the relatively low room-temperature ionic conductivity and interface issues. Anion-derived cation-anion aggregates (AGGs), derived from high-concentration liquid electrolytes, promote a stable solid-electrolyte interphase layer, which have gradually propelled their application in SPEs.

MXenes and MXene-based composites for biomedical applications.

MXenes, a novel class of two-dimensional materials, have recently emerged as promising candidates for biomedical applications due to their specific structural features and exceptional physicochemical and biological properties. These materials, characterized by unique structural features and superior conductivity, have applications in tissue engineering, cancer detection and therapy, sensing, imaging, drug delivery, wound treatment, antimicrobial therapy, and medical implantation. Additionally, MXene-based composites, incorporating polymers, metals, carbon nanomaterials, and metal oxides, offer enhanced electroactive and mechanical properties, making them highly suitable for engineering electroactive organs such as the heart, skeletal muscle, and nerves.

Recent Progress in Oxygen Reduction Reaction Toward Hydrogen Peroxide Electrosynthesis and Cooperative Coupling of Anodic Reactions.

Electrosynthesis of hydrogen peroxide (HO) via two-electron oxygen reduction reaction (2e ORR) is a promising alternative to the anthraquinone oxidation process. To improve the overall energy efficiency and economic viability of this catalytic process, one pathway is to develop advanced catalysts to decrease the overpotential at the cathode, and the other is to couple 2e ORR with certain anodic reactions to decrease the full cell voltage while producing valuable chemicals on both electrodes. The catalytic performance of a 2e ORR catalyst depends not only on the material itself but also on the environmental factors.

Mixed-Valence Coordination Strategy Creating Ordered Ternary Ultrasmall Homo-/Hetero-structures Driven by Lattice Match for Advanced Photochromism and Encryption Applications.

Overcoming the challenges of integrating disparate components in nanoarchitectures, this study introduces a straightforward strategy based on a mixed-valence coordination approach, creating an ordered ternary heterostructure integrated with ultrasmall homojunction. This singular ordered homojunction-heterostructure unites ultrathin 1D rutile TiO nanowires (NWs) and ultrathin anatase TiO NWs with 0D Prussian Blue Analogs (PBAs) nanoparticles (NPs), all exhibiting crystallographic oriented alignment with each other, forming a ternary mesocrystals. Experimental and theoretical insights disclose that the complex interplay between these dissimilar components is governed by a spontaneous lattice match effect, which not only optimizes but also directs the charge transfer, thereby enhancing both efficiency and stability.

Nanoporous Graphene with Encapsulated Multicomponent Carbide as High-Performance Binder-Free Lithium-Ion Battery Anodes.

Metal carbides are considered attractive lithium-ion battery (LIB) anode materials. Their potential practical application, however, still needs nanostructure optimization to further enhance the Li-storage capacity, especially under large current densities. Herein, a nanoporous structured multi-metal carbide is designed, which is encapsulated in a 3D free-standing nanotubular graphene film (MnNiCoFe-MoC@NG).

Digital Platform-Based Conceptual Framework for Food Environment Research in China.

China has dedicated significant efforts to preventing obesity, but the rising prevalence of overweight and obesity remains a pressing public health issue. Therefore, unique solutions are required to address this challenge in China. As a research priority, the food environment plays a pivotal role in addressing overweight and obesity.

Surface Nonbonding Oxygen State Regulation for Reversible Anionic Redox Chemistry in Li-rich Mn-based Layered Oxides.

Activated by the Li-O-Li configuration with nonbonding O2p state (lO2p), anionic redox reaction (ARR) in Li-rich layered oxides (LLOs) contributes to additional capacity but exhibits significant irreversibility, leading to severe surface oxygen loss. Herein, surface nonbonding oxygen state (SNBOS) is regulated by the integrated surface structure engineering to suppress surface oxygen loss and enhance the reversibility of ARR. On the outermost layer, the conversion of layered structure into a LiLaO2 layer and spinel phase structure eliminates lO2p, thereby preventing the activation of ARR and suppressing side reaction between electrolyte and oxidized oxygen ions.

Injectable Nanocomposite Hydrogels for Intervertebral Disc Degeneration: Combating Oxidative Stress, Mitochondrial Dysfunction, and Ferroptosis.

Intervertebral disc degeneration (IVDD) is a major cause of low back pain, where oxidative stress and mitochondrial dysfunction are key contributors. Additionally, ferroptosis, an iron-dependent form of cell death, is identified as a critical mechanism in IVDD pathogenesis. Herein, the therapeutic potential of gallic acid (GA)-derived PGA-Cu nanoparticles, enhanced with functional octapeptide (Cys-Lys-His-Gly-d-Arg-d-Tyr-Lys-Phe, SS08) to build the mitochondria-targeted nanoparticles (PGA-Cu@SS08), and embedded within a hydrogel matrix to form a nanocomposite hydrogel, is explored.

Rationalizing high-entropy catalytic self-Fenton pollutant degradation from an effective porous piezoelectric composite film.

As an emerging catalytic strategy, heterogeneous Piezo-Self-Fenton (EPSF) has demonstrated significant potential in fields such as environmental remediation and biomedicine in recent years. However, the catalytic reactions in this process are complex and diverse, and the understanding of high-entropy catalytic systems remains limited. In this study, we constructed a series of iron-based EPSF materials by incorporating various types of iron sources into MgO@rGO/PVDF-HFP composite piezoelectric films.

A Metal-Organic Framework with Mixed Electron Donor TTF and Electron Acceptor NDI Ligands for High-Performance Hybrid Lithium-Ion Capacitors.

Integrating mixed electron donor (D) and electron acceptor (A) ligands into metal-organic frameworks (MOFs) is an effective yet relatively unexplored approach for improving the anode performance of hybrid lithium-ion capacitors (HLICs). In this study, using an electron donor 2,6-bis(4'-pyridyl)tetrathiafulvalene and an electron acceptor ,'-bis(5-isophthalic acid) naphthalene diimide as ligands, a new Zn-TTF/NDI MOF () is constructed as a pseudocapacitive anode of HLICs. Crystallographic characterization revealed that MOF adopts a two-dimensional (2D) coordination network.

Associations of maternal age with outcomes in very low birth weight singleton infants: a retrospective study.

Background: With advances in perinatal medicine, there has been a rise in the preterm birth rate, especially the rate of very low birth weight (VLBW) and extremely low birth weight infants. Studies have shown that maternal age during pregnancy and at the time of delivery is associated with pregnancy complications and poor neonatal outcomes. Little is known about the effect of maternal age on the outcome of very low birth weight infants.

Perinatal testicular torsion diagnosed as an intraperitoneal mass: case report and literature review.

Perinatal testicular torsion is not common in clinic. We report our experience in treating such a condition in a 50-day boy with an intraperitoneal mass. The clinical manifestations, physical examination, imaging examination and treatment of the boy were retrospectively analyzed and the related literatures were reviewed.

Cystoscopy to investigate the prevalence of prostatic utricle cyst in boys with proximal hypospadias and its implications in medium-term follow-up.

Purpose: Prostatic utricle cyst (PUC) is known to be associated with hypospadias. We aimed to investigate the prevalence of PUC in children with proximal hypospadias by cystoscopy, and risk of symptom development after hypospadias repair.

Methods: We retrospectively reviewed the records of patients who underwent 2-stage repair for proximal hypospadias and had cystoscopy for PUC assessment over the period of January 2017-September 2022.

Prolene suture-assisted cystoscopic removal of double J ureteral stents in infants.

Objectives: The purpose of this study was to describe the prolene suture-assisted cystoscopic removal of double J ureteral stents in infants and summarize the safety, operability, and effectiveness of this approach.

Methods: The clinic data of patients who underwent double J ureteral stent removal by prolene suture-assisted cystoscopy were reviewed. The operation procedure was as follows: First, a folded 4-0 prolene suture was preset into the cystoscope sheath, and the telescope was placed.

Three new species of (Agaricales, Basidiomycota) from southern China.

Three new species of are discovered from southern China. is characterized by its small basidiomata, greenish-green pileus, slender stipe, narrow, and close lamellae. is characterized by its pubescent pileus when young, yellowish white to pale yellow lamellae that are lighter towards the margin, narrowly cylindrical to lageniform pleurocystidia, and absent cheilocystidia.

 gen. et sp. nov. (Mytilinidiaceae), and (Dactylosporaceae), a new lichenicolous species from Yunnan, China.

and are reported from China and identified through DNA sequence analyses (LSU, ITS, and 1-α) and morphological characteristics. Phylogenetic analysis showed that forms a distinct lineage within Mytilinidiaceae, closely related to the subclade, leading to the establishment of a new genus within this family. This saprotrophic species grows on the bark of , often surrounded by the thallus of species.

Synthesis of the aggregation pheromone of .

Herbst is a destructive stored product pest. The aggregation pheromone of this pest was prepared via a new and effective strategy. The key steps include the ring-opening reaction of chiral 2-methyloxirane, the stereospecific inversion of chiral secondary tosylate, LiCuCl-catalyzed coupling of tosylate with Grignard reagent, and oxidation with RuCl/NaIO

Analysis of single-cell and spatial transcriptomics in TNBC cell-cell interactions.

Triple-negative breast cancer (TNBC) is a highly malignant tumor in women, characterized by high morbidity, mortality, and recurrence rates. Although surgical treatment, radiotherapy, and chemotherapy are the mainstays of current treatment methods, the high heterogeneity of TNBC results in unsatisfactory outcomes with low 5-year survival rates. Rapid advancements in omics technology have propelled the understanding of TNBC molecular biology.

Significant association between systemic inflammation response index and prognosis in patients with urological malignancies.

Background: The systemic inflammation response index (SIRI) as an immune marker, is associated with prognosis of urological malignancies(UM). However, the conclusion remains controversial. Therefore, the objective of this study was to conduct a meta-analysis to comprehensively evaluate the predictive value of SIRI in patients with UM.

Animal models of post-acute COVID-19 syndrome: a call for longitudinal animal studies.

Animal models are indispensable for unraveling the mechanisms underlying post-acute sequelae of COVID-19 (PASC). This review evaluates recent research on PASC-related perturbations in animal models, drawing comparisons with clinical findings. Despite the limited number of studies on post-COVID conditions, particularly those extending beyond three months, these studies provide valuable insights.

Artesunate alleviated murine ulcerative colitis by regulating immune response through inhibiting endoplasmic reticulum stress.

Innate and adaptive immunity are intricately linked to the pathogenesis of ulcerative colitis (UC), with dysregulation of the Treg/Th17 balance and M2/M1 macrophage polarization identified as critical factors. Artesunate (ARS) has previously been shown to alleviate UC by inhibiting endoplasmic reticulum stress (ERS). To further investigate the regulatory effects of ARS on immune dysregulation associated with colitis and the role of ERS in this process, an experimental colitis model was established using dextran sulfate sodium (DSS).