Internet use and attitude toward aging among Chinese older adults: the mediating role of health.

Objectives: This research seeks to explore the relationship between Internet use and attitudes toward aging among older adults in China, with a particular emphasis on the mediating role of health in this correlation.

Methods: A national survey of 10,858 Chinese adults aged 60 and above was conducted, employing multiple linear regression and structural equation modeling to analyze the impact of Internet use on aging attitudes with health as a mediator.

Results: The research found a significant positive association between Internet use and positive aging attitudes ( = -1.

Construction and validation of a prediction model for fall risk in hospitalized older adults with osteoporosis.

Objective: The aim of this study is to develop and validate a prediction model for fall risk factors in hospitalized older adults with osteoporosis.

Methods: A total of 615 older adults with osteoporosis hospitalized at a tertiary (grade 3A) hospital in Nantong City, Jiangsu Province, China, between September 2022 and August 2023 were selected for the study using convenience sampling. Fall risk factors were identified using univariate and logistic regression analyses, and a predictive risk model was constructed and visualized through a nomogram.

Multifaceted impacts of double-aging neighborhood's built environments on SAIP: a deep dive into Chinese rapidly aging urban society.

Introduction: The healthy aging of older adults in dual-older adult communities is influenced by multiple factors, and understanding its underlying mechanisms can promote healthy aging among the older adults in a wide range of developing countries. This comprehensive study delves into the intricate interplay between multifaceted built environmental factors, and their direct and indirect effects on the successful AIP residing in double-aging neighborhoods.

Methods: Applying a series of HLM, the research meticulously explores the intricate links between SAIP and multi-scale aging spaces, including home space, community social participation, and built environments.

Dynamics of urban green spaces in a megacity under the green economy framework and their influencing factors: a case study of Chongqing urban area.

Introduction: In the context of escalating public health crises in megacities, promoting green and healthy urban spatial development is crucial. It not only contributes to economic growth and environmental sustainability but also significantly impacts the public health of urban residents.

Methods: This study utilized land use data from 2000 to 2021 in Chongqing, China, to investigate the characteristics and patterns of change in urban green space distribution.

Development of a multi-laboratory integrated predictive model for silicosis utilizing machine learning: a retrospective case-control study.

Objective: Due to the high global prevalence of silicosis and the ongoing challenges in its diagnosis, this pilot study aims to screen biomarkers from routine blood parameters and develop a multi-biomarker model for its early detection.

Methods: A case-control study was conducted to screen biomarkers for the diagnosis of silicosis using LASSO regression, SVM and RF. A sample of 612 subjects (half cases and half controls) were randomly divided into training and test groups in a 2:1 ratio.

How exercise frequency affects BMI: a nationwide cross-sectional study exploring key influencing factors, including dietary behavior.

Purpose: Body Mass Index (BMI) is an important indicator for assessing obesity and related health risks. With the rapid socio-economic development and changes in lifestyle, abnormal BMI (such as underweight, overweight, and obesity) has become an increasingly serious public health issue. This study aims to explore the impact of exercise frequency on BMI among Chinese adults aged 19 to 59, and to analyze the role of dietary behaviors in regulating BMI, providing a basis for BMI intervention strategies.

Study on the construction of multi-level protection system for non-emergency transfer under the perspective of structuring.

Introduction: The non-emergency transfer multi-level protection system is a pivotal livelihood endeavor in China, serving as a vital diversified component within the robust framework of a Chinese-style modern social security system. This system faces various challenges, including displacement of emergency capacity by non-emergency demands, uneven allocation of transfer resources, service quality variations, inadequate management structures, limited regulatory frameworks, and social acceptance issues.

Methods: Leveraging structural theory, this study analyzes the primary issues in the current implementation of China's non-emergency transfer security system.

Cyber anti-intellectualism and science communication during the COVID-19 pandemic: a cross-sectional study.

Background: During the COVID-19 pandemic, science communication played a crucial role in disseminating accurate information and promoting scientific literacy among the public. However, the rise of anti-intellectualism on social media platforms has posed significant challenges to science, scientists, and science communication, hindering effective public engagement with scientific affairs. This study aims to explore the mechanisms through which anti-intellectualism impacts science communication on social media platforms from the perspective of communication effect theory.

HIV-1 drug resistance and genetic transmission networks among patients with sexually transmitted HIV in Ningxia, China.

Background: Over the past decade, sexual transmission has become a dominant source of new HIV-1 infection in China. However, very few studies have been conducted to characterize the two sexual transmissions, homosexual and heterosexual transmission. This study was conducted to better understand the relationship between genotypes, drug resistance, and molecular transmission networks in two groups of sexually transmitted HIV-1 in Ningxia, China.

Do education, urbanization, and green growth promote life expectancy?

Introduction: Education (EDU) enhances life expectancy (LEF) by improving health literacy and access to healthcare, leading to healthier lifestyles. Urbanization (URB) fosters better healthcare infrastructure and access to essential services, although it must be managed to avoid negative environmental impacts. Green growth (GG) ensures sustainable development, reduces pollution and environmental risks, and contributes to longer, healthier lives.

Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study.

Background: Sarcopenia, sarcopenic obesity, and hypertension are all widespread public health problems in middle-aged and older populations, and their association is controversial. The purpose of this study is to analyze the relationship between obesity, sarcopenia, and sarcopenic obesity with hypertension in a middle-aged and older community population in China through a large-scale longitudinal design.

Methods: In this cohort study with 7 years of follow-up, the study population was drawn from participants in the China Health and Retirement Longitudinal Study (CHARLS) in 2011 and followed up in 2013, 2015, and 2018.

The neutrophil-lymphocyte ratio as a risk factor for all-cause mortality among individuals with resolved HBV infection: evidence from the NHANES 1999-2018.

Background: Inflammation is a critical component in the process of resolved hepatitis B virus (HBV) infection. The neutrophil-to-lymphocyte ratio (NLR) serves as a sensitive indicator of systemic inflammation and immune activation. Our study aimed to investigate the correlation between elevated NLR levels and the risk of all-cause mortality in patients with resolved HBV infection.

Digital technologies as solutions to China's aging population: a systematic review of their opportunities and challenges in rural development.

Introduction: Differences exist in the rate of aging between individuals residing in urban and rural areas in China, with rural areas experiencing a more pronounced impact. Smart aging represents a prevalent future trend in this regard, though its development will inevitably face challenges. However, studies focusing on rural areas are scarce.

Prediction of tuberculosis-specific mortality for older adult patients with pulmonary tuberculosis.

Background: This study aims to identify risk factors associated with tuberculosis-specific mortality (TSM) in older adult patients with pulmonary tuberculosis (TB) and to develop a competing risk nomogram for TSM prediction.

Methods: We conducted a retrospective cohort study and randomly selected 528 older adult pulmonary TB patients hospitalized in designated hospitals in Henan Province between January 2015 and December 2020. The cumulative incidence function (CIF) was calculated for both TSM and non-tuberculosis-specific mortality (non-TSM).

Potential profiling of social alienation in older female patients with stress urinary incontinence.

Background: With the global trend of aging, stress urinary incontinence is becoming more common in older adults, which may have some impact on patients' quality of life. Social alienation can generate negative emotions such as anxiety, depression, loneliness, and morbid stigma, and reduce patients' quality of life. However, the current status of social alienation is different among different older adult female patients with stress urinary incontinence.

Constructing a model of the factors related to the job wellbeing of preschool teachers in China: a grounded theory study.

Introduction: As educational management research evolves, leadership styles are increasingly recognized as crucial managerial skills. Among various leadership approaches, empowering leadership has been found to significantly enhance employee job performance and satisfaction. However, there is limited research exploring the relationship between empowering leadership and the job wellbeing of preschool teachers in the educational sector.

A cross-sectional study of parental perspectives on children about COVID-19 and classification using machine learning models.

Background And Objective: This study delves into the parenting cognition perspectives on COVID-19 in children, exploring symptoms, transmission modes, and protective measures. It aims to correlate these perspectives with sociodemographic factors and employ advanced machine-learning techniques for comprehensive analysis.

Method: Data collection involved a semi-structured questionnaire covering parental knowledge and attitude on COVID-19 symptoms, transmission, protective measures, and government satisfaction.

Associations between cardiovascular-kidney-metabolic syndrome and disability in activities of daily living: a nationwide longitudinal study among the middle-aged and older adults in China.

Background: Activities in daily living (ADLs) disability triggered by aging population and chronic diseases in the middle-aged and older adults has become a major public health challenge. Cardiovascular-kidney-metabolic (CKM) syndrome, as a combination of several chronic conditions, has not yet been studied to explore its association with ADLs disability. We examined the association between CKM syndrome and ADLs disability among middle-aged and older adults in China and whether it varied by age and socioeconomic status.

Assessing and projecting the global impacts of Alzheimer's disease.

Background: This study aims to assess the global burden of Alzheimer's disease (AD) from 1990 to 2030, with a focus on incidence, mortality, and disability-adjusted life years (DALY).

Methods: Data on the incidence rates, DALY rates, and death rates of AD across various geographic populations from 1990 to 2021 were obtained from the Global Burden of Disease (GBD) 2021 study. Generalized Additive Models (GAMs) were employed to forecast the disease burden from 2022 to 2030.

The Association Between Adiponectin Gene Polymorphism (rs1501299) and Metabolic Syndrome.

Objective: To investigate the allelic genotypes of the adiponectin (APN) gene polymorphisms (rs1501299) and its association with APN level among Mets patients.

Methods: A total of 410 patients with Mets and 203 healthy subjects were included in the study. The serum APN levels of the subjects were detected using enzyme-linked immunosorbent assay.

Transcript Changes of Placental Tissue in Gestational Diabetes Mellitus Based on Transcriptome Sequencing.

Purpose: This study aims to identify key genes that may be involved in the pathogenesis of gestational diabetes mellitus and to preliminarily elucidate the underlying mechanisms.

Methods: High-throughput transcriptome sequencing was employed to identify Differentially expressed genes (DEGs) in placental tissue samples of GDM and normal pregnant women. Functional and pathway analyses of these DEGs were conducted using bioinformatics databases.

PD(L)1 Inhibitors Plus Lenvatinib Vs Atezolizumab Plus Bevacizumab Combined With HAIC for Unresectable HCC: A Propensity Score Matching Study.

Purpose: To compare the clinical outcomes of different systemic therapies, specifically PD(L)1 inhibitors plus Lenvatinib versus Atezolizumab plus Bevacizumab, when combined with hepatic arterial infusion chemotherapy (HAIC) based on the FOLFOX regimen (oxaliplatin, fluorouracil, and leucovorin) as first line treatment for unresectable hepatocellular carcinoma.

Patients And Methods: This real-world retrospective study enrolled 294 patients with unresectable HCC. All patients received HAIC in combination with either PD(L)1 inhibitors plus Lenvatinib (PLEN-HAIC) or Atezolizumab plus Bevacizumab (AT-HAIC).

Increased cardiac macrophages in -deficient hearts: revealing a potential role for macrophage in responding to embryonic myocardial abnormalities.

Macrophages are known to support cardiac development and homeostasis, contributing to tissue remodeling and repair in the adult heart. However, it remains unclear whether embryonic macrophages also respond to abnormalities in the developing heart. Previously, we reported that the structural protein Sorbs2 promotes the development of the second heart field, with its deficiency resulting in atrial septal defects (ASD).

Case Report: Novel variants cause atypical adenosine deaminase 2 deficiency.

Case Presentation: A girl aged 2 years and 5 months presented to the hospital with chief complaints of intermittent fever and weakness of the left limb for more than 1 month. The child had transient urticaria appearing on her face for 5 days. The inflammatory biomarkers were significantly increased.

Classical and machine learning tools for identifying yellow-seeded by fusion of hyperspectral features.

Introduction: Due to its favorable traits-such as lower lignin content, higher oil concentration, and increased protein levels-the genetic improvement of yellow-seeded rapeseed has attracted more attention than other rapeseed color variations. Traditionally, yellow-seeded rapeseed has been identified visually, but the complex variability in the seed coat color of has made manual identification challenging and often inaccurate. Another method, using the RGB color system, is frequently employed but is sensitive to photographic conditions, including lighting and camera settings.