Case Report: Diagnosis and treatment of with central nervous system anomalies in one patient.

Introduction: This article reports a detailed case of a patient with who exhibited epileptic status and dermatologic symptoms.

Case Presentation: A 5-month-old female patient was brought to our hospital due to status epilepticus, with erythematous vesicular skin lesions on her trunk and extremities. Routine magnetic resonance imaging revealed infarction, ischemia, and encephalomalacia.

Solar Wind Magnetosphere Ionosphere Link Explorer (SMILE): Science and Mission Overview.

The Solar wind Magnetosphere Ionosphere Link Explorer (SMILE) was proposed to the Chinese Academy of Science (CAS) and the European Space Agency (ESA) following a joint call for science missions issued in January 2015. SMILE was proposed by a team of European and Chinese scientists, led by two mission Co-PIs, one from China and one from Europe. SMILE was selected in June 2015, and its budget adopted by the Chinese Academy of Sciences in November 2016 and the ESA Science Programme Committee in March 2019, respectively.

Evaluation of an oral health education training program for kindergarten teachers.

Objectives: This study aims to examine kindergarten teachers' satisfaction and their perceived impact of an oral health education (OHE) training program.

Methods: This study followed the steps outlined in the Program Evaluation Standards in Public Health recommended by the Centers for Disease Control and Prevention. All kindergarten teachers in Hong Kong were invited to attend the OHE training.

Development of photodynamic therapy in treating oral diseases.

The morbidity of oral disorders, including gingivitis, caries, endodontic-periodontal diseases, and oral cancer, is relatively high globally. Pathogenic cells are the root cause of many oral disorders, and oral therapies depend on eradicating them. Photodynamic therapy (PDT) has been established as a potential and non-invasive local adjuvant treatment for oral disorders.

Multiomics Analysis of Exportin Family Reveals XPO1 as a Novel Target for Clear Cell Renal Cell Carcinoma.

Recently, exportin gene family members have been demonstrated to play essential roles in tumor progression. However, research on the clinical significance of exportin gene family members is limited in clear cell renal cell carcinoma (ccRCC). Pan-cancer data, ccRCC multiomics data, and single-cell sequence were included to analyze the differences in DNA methylation modification, single nucleotide variations (SNVs), copy number variations (CNVs), and expression levels of exportin gene family members.

Molecular modeling to elucidate the dynamic interaction process and aggregation mechanism between natural organic matters and nanoplastics.

The interactions of nanoplastics (NPs) with natural organic matters (NOMs) dominate the environmental fate of both substances and the organic carbon cycle. Their binding and aggregation mechanisms at the molecular level remain elusive due to the high structural complexity of NOMs and aged NPs. Molecular modeling was used to understand the detailed dynamic interaction mechanism between NOMs and NPs.

The Mechanism of Acupuncture Therapy for Migraine: A Systematic Review of Animal Studies on Rats.

Background: Acupuncture has long been used for migraine treatment as it is convenient for use and has remarkable efficacy. The acupuncture-based comprehensive treatment plan has been widely recognized for migraine prevention and treatment. However, the mechanism underlying acupuncture efficacy in migraine treatment is not yet completely understood.

Auricular Acupuncture for Perioperative Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Purpose: We conducted a more comprehensive systematic review and meta-analysis to evaluate the effectiveness of auricular acupuncture (AA) in perioperative pain management.

Methods: Randomized controlled trials (RCTs) findings were retrieved from the Embase, Cochrane Central Register of Controlled Trials, PubMed, Web of Science, Chinese Biomedical Literature Database, Wanfang, VIP, and China National Knowledge Infrastructure databases from their inception to March 2024 using the search terms "pain", "auriculotherapy", and "randomized controlled trial". The experimental group was treated with AA alone or in combination with analgesic drugs, whereas the control group was treated with sham auricular acupuncture, placebo, conventional treatment, or no treatment.

The amino acid permease contributes to tomato growth and salt tolerance by mediating branched-chain amino acid transport.

Branched-chain amino acids (BCAAs) are essential amino acids in tomato () required for protein synthesis, which also modulate growth and abiotic stress responses. To date, little is known about their uptake and transport in tomato especially under abiotic stress. Here, the tomato () gene was identified as an amino acid transporter that restored mutant yeast cell growth on media with a variety of amino acids, including BCAAs.

The GRAS transcription factor PtrPAT1 of functions in cold tolerance and modulates glycine betaine content by regulating the -like gene.

GRAS, termed after gibberellic acid insensitive (GAI), RGA (repressor of GA1), and SCR (scarecrow), is a plant-specific transcription factor crucial for plant development and stress response. However, understanding of the functions played by the GRAS members and their target genes in citrus is limited. In this study, we identified a cold stress-responsive GRAS gene from , designated as PtrPAT1, by yeast one-hybrid library screening using the promoter of , a betaine aldehyde dehydrogenase (BADH)-like gene.

NpCIPK6-NpSnRK1 module facilitates intersubgeneric hybridization barriers in water lily () by reducing abscisic acid content.

Prefertilization hybridization barriers are the main causes of intersubgeneric hybridization challenges in water lily. However, the mechanism underlying low compatibility between pollen and stigma of water lily remains unclear. This study demonstrates that CBL-interacting protein kinase 6 (CIPK6) responded to the signaling exchange between incompatible pollen and stigma through interactions with SNF1-related kinase 1 (SnRK1) and promotes the accumulation of SnRK1 protein.

Glycerophosphodiester phosphodiesterase 1 mediates G3P accumulation for Eureka lemon resistance to citrus yellow vein clearing virus.

Glycerophosphodiester phosphodiesterase 1 (GDPD1) plays an important function in the abiotic stress responses and participates in the accumulation of sn-glycerol-3-phosphate (G3P) in plants, which is key to plant systemic acquired resistance (SAR). However, the role of GDPD1 in plant responses to biotic stress remains poorly understood. This study characterized the antivirus function of the gene (designated as ) from Eureka lemon.

Effects of non-pharmacological interventions on the depressive outcomes in people with mild cognitive impairment: an overview of systematic reviews.

Objective: This study aimed to summarize and assess the certainty of evidence of non-pharmacological interventions (NPIs) on the depressive outcomes in people with mild cognitive impairment (MCI) based on published systematic reviews (SRs).

Method: Databases including PubMed, EMBASE, PsycINFO, the Cochrane Database of Systematic Reviews, CNKI, CBM, Wanfang and VIP database were searched from their inception to June 6, 2023. The methodological quality of the SRs was evaluated using the AMSTAR2 tool, and the quality of evidence was assessed using the Grading of Recommendation Assessment, Development and Evaluation (GRADE) framework.

An ARFID case report assessment with 18F-FDG PET/MRI and treatment with olanzapine, escitalopram and fluoxetine in adult.

Background: Avoidant/restrictive food intake disorder (ARFID), a DSM-5-introduced eating disorder, is increasingly prevalent and challenging to treat, primarily affecting children and adolescents, with limited adult case reports. This rarity in adults leads to misdiagnosis or underdiagnosis, and treatment experiences are scarce.

Case Presentation: This report details an adult ARFID case, where the patient's fear of food intake followed gastric damage from corn ingestion, resulting in a restrictive diet of rice porridge due to gastric pain.

Why can parents' phubbing affect mobile phone addiction? Perspective of the I-PACE model.

Objective: Based on the I-PACE model, this study investigated the longitudinal relationship between parents' phubbing and mobile phone addiction, as well as the serial mediating effects of maladaptive cognition and ego depletion.

Methods: A longitudinal study, with data collected at two time points over a six-month interval to test the proposed hypotheses. The independent variable was measured at Time 1 (T1), while the mediators and dependent variables were assessed at Time 2 (T2).

EPO-Mimetic Peptide Pegmolesatide Therapy for Pure Red Cell Aplasia in a Patient with Non-dialysis-dependent Type 1 Diabetic Nephropathy: A Case Report.

Pure red cell aplasia (PRCA) is a rare complication of erythropoietin (EPO) therapy, characterized by a severe deficiency in red blood cell production. There is no guideline on the treatment for PRCA because there have been too few cases to perform prospective cohort studies. The main treatments for PRCA include immediate cessation of EPO, restrictive transfusion, and immunosuppressive therapies.

The relationship between impostor phenomenon and emotional exhaustion among Chinese nurses: the mediating role of bi-directional work-family conflict.

Aims: The study aims to explore the relationship between impostor phenomenon and emotional exhaustion among nurses and to examine the potential mediating role of bi-directional work-family conflict.

Methods: A cross-sectional survey using convenience sampling was conducted from January to April 2023, involving 4,088 Chinese nurses. Of those, 3,977 nurses across 43 public hospitals completed the web-based survey that included a sociodemographic information questionnaire, the short Clance Impostor Phenomenon Scale, the Bi-directional Scale of Work-Family Conflict, and the Emotional Exhaustion Scale.

Internet use and attitude toward aging among Chinese older adults: the mediating role of health.

Objectives: This research seeks to explore the relationship between Internet use and attitudes toward aging among older adults in China, with a particular emphasis on the mediating role of health in this correlation.

Methods: A national survey of 10,858 Chinese adults aged 60 and above was conducted, employing multiple linear regression and structural equation modeling to analyze the impact of Internet use on aging attitudes with health as a mediator.

Results: The research found a significant positive association between Internet use and positive aging attitudes ( = -1.

Construction and validation of a prediction model for fall risk in hospitalized older adults with osteoporosis.

Objective: The aim of this study is to develop and validate a prediction model for fall risk factors in hospitalized older adults with osteoporosis.

Methods: A total of 615 older adults with osteoporosis hospitalized at a tertiary (grade 3A) hospital in Nantong City, Jiangsu Province, China, between September 2022 and August 2023 were selected for the study using convenience sampling. Fall risk factors were identified using univariate and logistic regression analyses, and a predictive risk model was constructed and visualized through a nomogram.

Multifaceted impacts of double-aging neighborhood's built environments on SAIP: a deep dive into Chinese rapidly aging urban society.

Introduction: The healthy aging of older adults in dual-older adult communities is influenced by multiple factors, and understanding its underlying mechanisms can promote healthy aging among the older adults in a wide range of developing countries. This comprehensive study delves into the intricate interplay between multifaceted built environmental factors, and their direct and indirect effects on the successful AIP residing in double-aging neighborhoods.

Methods: Applying a series of HLM, the research meticulously explores the intricate links between SAIP and multi-scale aging spaces, including home space, community social participation, and built environments.

Dynamics of urban green spaces in a megacity under the green economy framework and their influencing factors: a case study of Chongqing urban area.

Introduction: In the context of escalating public health crises in megacities, promoting green and healthy urban spatial development is crucial. It not only contributes to economic growth and environmental sustainability but also significantly impacts the public health of urban residents.

Methods: This study utilized land use data from 2000 to 2021 in Chongqing, China, to investigate the characteristics and patterns of change in urban green space distribution.