Lower red blood cell count is a risk factor for higher D-dimer level in patients with spinal cord injury: A five year retrospective cross-sectional study.

Objectives: This study aims to elucidate the relationship between red blood cell (RBC) count and D-dimer levels in patients with spinal cord injury, with the goal of identifying potential therapeutic targets for minimizing D-dimer levels.

Study Design: An observational, retrospective, cross-sectional, single center study.

Setting: Individuals with SCI (576 cases) admitted to a rehabilitation medicine department.

Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis.

Objective: The aim of this study was to examine if tranexamic acid (TXA) can assist in improving outcomes of arthroscopic rotator cu! repair (RCR).

Methods: The databases of PubMed, Embase, Web of Science, CENTRAL, and Scopus were searched for all types of studies examining the e"cacy of TXA for arthroscopic RCR. Twelve studies, 10 randomized controlled trials (RCTs), and 2 retrospective studies were considered eligible.

Chrysanthemum extract mitigates high-fat diet-induced inflammation, intestinal barrier damage and gut microbiota disorder.

An effective intervention for obesity without side effects is needed. Chrysanthemum may be the preferred choice due to its influence in the improvement of glycolipid metabolism. This study assessed the efficacy of chrysanthemum and its flavonoids in mitigating high-fat diet (HFD) induced obesity, focusing on the integrity of the intestinal barrier, inflammation, and gut microbiota.

Ultrarapid and efficient sequestration of iodate and iodide with a pillar[5]arene-based cationic polymeric network.

A macrocycle-based approach to the construction of a cationic polymeric network with pillar[5]arene as the node for efficient sequestration of hazardous IO and I is presented. Ultrafast kinetics ( 4 min) were achieved along with excellent adsorption capacities for both IO (456 mg g) and I (370 mg g), good selectivity, and outstanding reusability. This work showcases the merits of pillar[5]arene as nodes in cationic adsorption materials in the removal of anionic iodine species.

The impact of antimony on all-inorganic lead-free perovskites: progress in optical advancement and applications.

The incorporation of Sb ions into all-inorganic halide lead-free perovskites bestows them with remarkable photoluminescence characteristics, including an extensive color tuning range, elevated photoluminescence quantum yield (PLQY), and reversible color transitions, which hold significant promise for applications in light-emitting diodes, anti-counterfeiting encryption technologies, and photodetectors. Sb ions not only create new optical absorption channels but also can be integrated into these materials as activators or sensitizers to modulate the bandgap and band structure. This review focuses on the optical properties of Sb ion-doped lead-free halide perovskites while examining potential energy transfer pathways across various doping systems.

The Dual Effect of Work Rumination in the Relationship Between Challenge Stress and Innovative Behavior: A Moderated Mediation Model of Information Literacy.

Innovation in healthcare is crucial for enhancing patient care and operational efficiency. Nurses often experience stress that may impede the process of innovation. This study utilizes the Job Demands-Resources model and Cognitive Appraisal Theory to investigate the impact of challenge stress, work rumination, and information literacy on the expression of innovative behaviors among nurses.

Advanced measurement methods for high-power gallium nitride high electron mobility transistors.

The testing and modeling of semiconductor devices are the foundation of circuit design. The issue of high-power device testing urgently needs to be solved as the power level of the devices under test (DUTs) increases. This work proposes advanced measurement methods based on three aspects of "measuring capability, security, and stability" with a focus on the features of high output power, easy self-oscillation in mismatch tests, and safety risk in the measurement system of high-power transistors.

Two-dimensional BiTeX crystals with persistent luminescence induced by photochemical reactions.

Two-dimensional (2D) materials are highly valued for their unique properties and potential applications, as they can display exotic behaviors differing from those of their bulk forms. Research on elementary and binary solids has been making great progress recently, while synthesizing multi-component 2D materials experimentally remains a challenge, despite the possibility of greatly extending the number of members of the 2D realm. In this study, we synthesized ternary BiTeX (X = Cl, Br, I) nanosheets with high crystallinity through an electrochemical exfoliation method.

Visible-light-promoted cascade cyclization of -arylacrylamides with bromomethyl sulfone: access to sulfonylmethylated phenanthridines.

We present a visible-light-promoted radical cascade cyclization reaction sulfonylmethylation, cyano insertion, and radical cyclization of unactivated alkenes bearing cyano groups. This strategy enables the rapid synthesis of sulfonylmethylated phenanthridines under mild conditions with broad substrate compatibility, operational simplicity, and mild reaction conditions. The developed approach provides a novel pathway for assembling complex polycyclic nitrogen-containing frameworks, addressing a critical synthetic challenge and expanding the toolbox of photochemical transformations in organic synthesis.

High-Performance Oxide Crystal BaTeWO X-ray Detector with High Stability, Low Detection Limit, and Ultralow Dark Current Drift.

X-ray detection materials and devices have received widespread attention due to their irreplaceable role in the medical, industrial, and military fields. In this paper, BaTeWO (BTW) crystal containing lone pairs of electrons with large atomic numbers and high density is reported as a new type of oxide crystal X-ray detection material. The anisotropic X-ray detection performance of the BTW single crystal (SC) is systematically studied.

dynamics of rumen microbiota and fermentation profiles with Antler growth of Sika deer.

The rumen microbiota plays a vital role in the nutrient metabolism affecting the growth of velvet antler. However, the fermentation patterns and dynamics of the rumen microbiota across growth stages of velvet antler remain largely unexplored. Here, we employed an fermentation approach to assess fermentation parameters and microbial composition in the rumen liquid of sika deer during the early growth (EG), metaphase growth (MG), and fast growth (FG) phases .

Interactions between gut microbes and host promote degradation of various fiber components in Meishan pigs.

Unlabelled: Although metagenomic investigations into microbial fiber-degrading capabilities are currently prevalent, there is a notable gap in research concerning the regulatory mechanisms underpinning host-microbiota interactions that confer tolerance to high-fiber diets in pigs. In this study, 28 Meishan (MS) and 28 Large White (LW) pigs were subjected to feeding experiments involving various fiber levels. Subsequently, multi-omics was employed to investigate the influence of host-microbiota interactions on the fiber degradation of pigs.

NIR-II absorption and photothermal conversion in a photochromic metal-organic framework based on -2,2'-biquinoline-4,4'-dicarboxylate.

A BCA -coordinated MOF (1) was initially discovered to exhibit electron transfer photochromism. Remarkably, the photogenerated radicals (1P) showed a maximum absorption enhancement peak at 1158 nm, resulting from the synergistic effects of planar π-conjugation induced by -coordination and π-π interactions among [BCA]˙˙ radicals, thereby promoting the NIR-II photothermal effect.

c-di-GMP phosphodiesterase ProE interacts with quorum sensing protein PqsE to promote pyocyanin production in .

The universal bacterial second messenger bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) plays critical roles in regulating a variety of bacterial functions such as biofilm formation and virulence. The metabolism of c-di-GMP is inversely controlled by diguanylate cyclases (DGCs) and phosphodiesterases (PDEs). Recently, increasing studies suggested that the protein-protein interactions between DGCs/PDEs and their partners appear to be a common way to achieve specific regulation.

Inhibiting NLRP3 enhances cellular autophagy induced by outer membrane vesicles from .

The bacterium is able to invade lung epithelial cells and survive intracellularly. During this process, it secretes outer membrane vesicles (OMVs), however, it is currently unclear how OMVs from (PA-OMVs) affect lung epithelial cells and their impact on oxidative stress, autophagy, and other physiological activities of lung epithelial cells. In this study, we found that PA-OMVs activated oxidative stress and autophagy in cells.

Systematic analyses uncover robust salivary microbial signatures and host-microbiome perturbations in oral squamous cell carcinoma.

Unlabelled: Oral squamous cell carcinoma (OSCC) is a prevalent malignancy in the oral-maxillofacial region with a poor prognosis. Oral microbiomes play a potential role in the pathogenesis of this disease. However, findings from individual studies have been inconsistent, and a comprehensive understanding of OSCC-associated microbiome dysbiosis remains elusive.

Exploring the growing phase forest musk deer () dietary energy requirements based on growth performance and gut microbiota analysis.

Unlabelled: The forest musk deer (FMD) farming industry is currently experiencing rapid growth, yet the dietary energy requirements for FMD remain unclear. Therefore, we explored the optimal dietary digestible energy (DE) for growing phase FMD by providing three diets with different DE levels and analyzing changes in gut microbiota. A total of 20 six-month-old FMD were used in a 62-day trial.

A point mutation in a like gene in enhances the anticorrosion activity.

The protection of steel based on microbial biomineralization has emerged as a novel and eco-friendly strategy for corrosion control. However, the molecular basis of the biomineralization process in mineralization bacteria remains largely unexplored. We previously reported that EPS+ strain provides protection against steel corrosion by forming a hybrid biomineralization film.

Fermentative profile and bacterial community structure of whole-plant triticale silage () with or without the addition of and .

This study aimed to investigate the effects of and on the chemical composition, fermentation characteristics, bacterial communities, and predicted metabolic pathways of whole-plant triticale silage (). Fresh triticale harvested at the milk stage was ensiled in sterile distilled water (CON), (ST), (LP), and a combination of and (LS) for 3, 7, 15, and 30 days. During ensiling, the pH and water-soluble carbohydrate (WSC) content in the inoculated groups was significantly lower than those in the CON group ( < 0.

Determination of 36 non-phthalate plasticizers with the QuEChERS method in milk powder by gas chromatography coupled with quadrupole/orbitrap high-resolution mass spectrometry.

A method involving gas chromatography coupled with quadrupole/orbitrap high-resolution mass spectrometry (GC-Q/Orbitrap HRMS) with the QuEChERS method was developed to analyze 36 non-phthalate plasticizers in milk powder products. The samples were dissolved in 20% NaCl, extracted with acetonitrile, and purified using silica, PSA, and C. The results showed the excellent linear relationship of the calibration curves of 36 non-phthalate plasticizers in the range of 10-1000 ng mL, with correlation coefficients () not less than 0.

mSphere of Influence: Seeking the unseen fungi in tumors.

Ningning Liu works in the field of fungal infection and cancer progression, with a particular focus on the mechanism of host-pathogen interaction. In this mSphere of influence article, he reflects on how papers entitled "The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL," by B. Aykut, S.

Relationship between the and the gene copy number variation and growth traits in different cattle breeds.

Copy number variations (CNV) are important genetic variations. The endogenous factors cobalamin receptor () and MIA SH3 domain ER-derived factor 3 () are associated with bone/muscle development and intramuscular fat deposition. There have been no reports on the effects of and CNVs on growth traits of Chinese cattle.

Real-world safety evaluation of brivaracetam: insights from the US FDA adverse event reporting system.

Background: Brivaracetam (BRV) is a novel drug for the treatment of epilepsy. This study aimed to detect and characterize adverse events (AEs) associated with BRV from the first quarter of 2016 to the second quarter of 2024 using the U.S.

Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma.

In this study, we find that Mif expression is associated with tumor growth and aggressiveness, specifically in tumors with low heterogeneity. These findings could facilitate the development of new strategies to treat patients with homogeneous, high MIF-expressing tumors that are unresponsive to immune checkpoint therapy.

APOC1 knockdown induces apoptosis and decreases angiogenesis in diffuse large B-cell lymphoma cells through blocking the PI3K/AKT/mTOR pathway.

Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous metastatic lymphoma that can be treated by targeting angiogenesis. Apolipoprotein C1 (APOC1) plays a significant role in the proliferation and metastasis of various malignant tumors; however, its role in DLBCL-particularly its effects on angiogenesis-remains largely unexplored. This study investigates the correlation between APOC1 expression and patient prognosis in DLBCL.