3,310,293 results match your criteria: "China; China-UK Institute for Frontier Science[Affiliation]"

Tearing of the subscapularis tendon is a common shoulder injury that typically requires arthroscopic repair. The suture-passing device is a standard tool for repairing the subscapularis tendon. However, it poses the risk of device breakage and may cause additional damage to the tendon.

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Objective: Although an association exists between dietary habits and head and neck cancer (HNC), the direct cause-and-effect connection remains elusive. Our objective was to investigate the causal associations between dietary factors and the likelihood of developing HNC.

Methods: Genome-wide association study (GWAS) summary statistics for dietary habits were screened from the UK Biobank, the OncoArray Oral Cavity and Oropharyngeal Cancer consortium, and the FinnGen biobank for HNC.

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Loneliness and Social Isolation with Risk of Incident Non-alcoholic Fatty Liver Disease, UK Biobank 2006 to 2022.

Health Data Sci

January 2024

National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China.

Although loneliness and social isolation are proposed as important risk factors for metabolic diseases, their associations with the risk of non-alcoholic fatty liver disease (NAFLD) have not been elucidated. The aims of this study were to determine whether loneliness and social isolation are independently associated with the risk of NAFLD and to explore potential mediators for the observed associations. In this large prospective cohort analysis with 405,073 participants of the UK Biobank, the status of loneliness and social isolation was assessed through self-administrated questionnaires at study recruitment.

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Inflammatory Markers and Risk of Parkinson's Disease: A Population-Based Analysis.

Parkinsons Dis

December 2024

Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, 42 Shangyihao Yizhi Street, Zigong, Sichuan, China.

Parkinson's disease (PD) is an important cause of neurological dysfunction, and the aim of this study was to explore whether neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), systemic inflammatory response (SIRI), and systemic immune inflammation (SII) are associated with the risk of developing PD. Based on this, we may identify people at high risk for PD and intervene early. Our study included 31,480 participants from the National Health and Nutrition Examination Survey (NHANES) between 2001 and 2018.

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The development of ultraviolet (UV) shielding materials is of great importance to protect human health and prevent the degradation of organic matter. However, the synthesis of highly efficient UV shielding polymer nanocomposites is currently limited by the agglomeration of inorganic anti-UV nanoparticles (NPs) within the polymer matrix and the limited absorption spectrum of UV shielding agents. In this study, highly effective manganese doped carbon quantum dots@halloysite nanotube composites (Mn-CDs@HNTs/PAS) were successfully synthesized by loading manganese-doped carbon quantum dots (Mn-CDs) into UV shielding effective halloysite nanotubes (HNTs) via the solvothermal method, followed by polymerization modification (PAS).

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Identification of potential MMP-8 inhibitors through virtual screening of natural product databases.

In Silico Pharmacol

January 2025

College of Chemistry and Chemical Engineering, China University of Petroleum, Qingdao, 266580 China.

Matrix metalloproteinase-8 (MMP-8), a type II collagenase, is a key enzyme in the degradation of collagens and is implicated in various pathological processes, making it a promising target for drug discovery. Despite advancements in the development of MMP-8 inhibitors, concerns over potential adverse effects persist. This study aims to address these concerns by focusing on the development of novel compounds with improved safety profiles while maintaining efficacy.

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To explore the experience of post-traumatic growth among parents of children with biliary atresia undergoing living-related liver transplantation.: Participants were recruited within 2 weeks of their child's transplant surgery using purposive sampling. Transcripts were analyzed using Colaizzi's descriptive analysis framework, with collaborative analysis conducted using NVivo 12 software and a post-traumatic growth model.

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Salt is a major abiotic factor significantly affecting plant growth and development. Alfalfa (Medicago sativa L.), a crucial perennial crop for livestock feed, shows significant differences in salt tolerance among different varieties.

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Introduction: A number of papers have reported on stressors to students in the dental curriculum. This paper analyses perceptions of strategies to improve well-being among final-year dental students in a dental curriculum.

Methods: A literature review was performed to create a question guide to explore issues of wellness and stress in a dental curriculum.

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Objectives: Dual energy x-ray absorptiometry (DXA) provides incomplete information about bone strength. There are few data on the relationship between osteoporosis-related examinations and bone strength. The objective of the present study was to determine which osteoporosis-related examinations best predicted trabecular bone strength, and to enhance a formula for predicting bone strength on the basis of bone density examination.

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The effective S-scheme homojunction relies on the precise regulation of band structure and construction of advantaged charge migration interfaces. Here, the electronic structural properties of g-C3N4 were modulated through meticulous polymerization of self-assembled supramolecular precursors. Experimental and DFT results indicate that both the intrinsic bandgap and surface electronic characteristics were adjusted, leading to the formation of an in-situ reconstructed homojunction interface facilitated by intrinsic van der Waals forces.

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Ischemia reperfusion-induced myocardial injury is a prominent pathological feature in patients with coronary artery disease, contributing to significant mortality and morbidity rates. Mangiferin (MGF), the main active ingredient extracted from Anemarrhena asphodeloides Bge, has anti-inflammatory, anti-oxidation, anti-diabetes, and anti-tumor effects. The present study confirmed that the GAS6/Axl pathway was identified as a promising novel target for the treatment of myocardial ischemia reperfusion (IR) injury.

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Asynchronous Embryo Transfer in Ewes.

Reprod Domest Anim

January 2025

College of Animal Science and Technology, Hebei Technology Innovation Center of Cattle and Sheep Embryo, Hebei Agricultural University, Baoding, Hebei, China.

The aim of the present study was to evaluate the effects of spatially and/or temporally asynchronous transfer of in vivo embryos at different stages in ewes during the breeding season. Four experiments were carried out. In Experiment 1, 207 blastocysts that had been frozen and thawed were transferred into the oviducts of 43 day two recipients, the oviducts of 23 day six recipients, and the uteri of 141 day six recipients, respectively.

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Purpose: To investigate the safety and efficacy of endovascular embolization combined with external drainage for poor-grade ruptured cerebral aneurysms and risk factors.

Materials And Methods: Forty-six patients with poor-grade ruptured cerebral aneurysms treated with endovascular embolization combined with decompressive craniectomy and drainage were retrospectively enrolled.

Results: Coil embolization alone was performed in 29 (63.

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An 18-connected wheel-shaped molybdenum(V) nickel-phosphate cluster for photoelectrochemical sensing of levofloxacin.

Chem Commun (Camb)

January 2025

Hebei Technology Innovation Center for Energy Conversion Materials and Devices, National Demonstration Center for Experimental Chemistry Education, College of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang, Hebei 050024, P. R. China.

An 18-connected {MoNiP}-based 2-D layered network was constructed for photoelectrochemical sensing of levofloxacin, and it represents the highest connection number of the {MoNiP} wheel cluster to date. The detection limit is as low as 6.46 nM with a high sensitivity of 110.

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Polymer composite materials encounter considerable challenges in sustaining superior tribological properties at high rotational speeds. Inspired by the microstructure of dragonfly wings, a novel thermally stable and ambient pressure curing poly(urea-imide) resin (PURI) with excellent tribological properties has been eco-friendly synthesis using bio-based greener solvents. Furthermore, The PURI composites enhanced with polyether ether ketone (PEEK) and Polytetrafluoroethylene (PTFE) blended fabrics demonstrate excellent mechanical, with tensile strengths exceeding 175 MPa.

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Alluaudite-type NaFe(SO) (NFS) with high theoretical energy density is regarded as the promising cathode of sodium-ion batteries (SIBs), while practical rate and cyclic performances are still hindered by intrinsic poor conductivity. Here, a facile method is developed, collaborating high-boiling organic solvents assisted colloidal synthesis (HOS-CS) with sintering for tailoring NaFe(SO) nanocrystals decorated by conductive carbon network toward high-rate-capability cathode of SIBs. Impressively, the as-prepared NaFe(SO)@MC provides 60.

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Background: Cicatricial lower-eyelid ectropion is a serious complication resulting from undesired lower lid blepharoplasty or impaired wound healing. Surgical treatment for ectropion is challenging for oculoplastic surgeons due to the unpredictability of surgical outcome and the difficulty of surgical design.

Objectives: The authors aimed to fully describe the surgical decision-making strategy for cicatricial ectropion, and to potentially enhance treatment outcomes.

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Facile Design of Highly Stretchable and Conductive Crumpled Graphene/NiS Films for Multifunctional Applications.

Small Methods

January 2025

Fujian Provincial Key Laboratory of Functional Marine Sensing Materials, College of Material and Chemical Engineering, Minjiang University, Fuzhou, 350108, P. R. China.

The cost-effective and scalable synthesis and patterning of soft nanomaterial composites with improved electrical conductivity and mechanical stretchability remains challenging in wearable devices. This work reports a scalable, low-cost fabrication approach to directly create and pattern crumpled porous graphene/NiS nanocomposites with high mechanical stretchability and electrical conductivity through laser irradiation combined with electrodeposition and a pre-strain strategy. With modulated mechanical stretchability and electrical conductivity, the crumpled graphene/NiS nanocomposite can be readily patterned into target geometries for application in a standalone stretchable sensing platform.

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Isomer-Effects of Aminophenol Decorated Gold Nanoclusters for HO Photoproduction via Two-Step One-Electron Oxygen Reduction Reaction.

Small

January 2025

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, P. R. China.

Gold (Au) nanoclustersare promising photocatalysts for biomedicine, sensing, and environmental remediation. However, the short carrier lifetime, inherent instability, and unclear charge transfer mechanism hinder their application. Herein, the Au nanoclusters decorated with three different isomers of o-Aminophenol, m-Aminophenol, and p-Aminophenol are synthesized, namely o-Au, m-Au, and p-Au, which achieve efficient hydrogen peroxide (HO) photoproduction through two-step one-electron oxygen reduction reaction (ORR).

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In sodium-ion batteries, the layered transition metal oxides used as cathode often experience interlayer sliding of interlayer spacing and lattice variations during charge/discharge, leading to structural damage and capacity degradation. To address this challenge, a La doping strategy guided by Bayesian optimization has been employed to prepare the high-performance O3-NaNiMnCuLaO (NMCL) cathode material. Density functional theory calculations reveal that the O 2p orbital overlaps with the t orbital of transition metals in NMCL, facilitating the formation of Na-O-La bonds and promoting the oxygen redox reaction kinetics.

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Photonic crystals (PC) play a key role in optical field modulation due to their unique photonic band gaps (PBGs). Anodic aluminum oxide (AAO) prepared by pulse anodization is a promising candidate for PC devices. In this research, an AAO-based PC with multi-band was fabricated on a single-slice & single-material film, which exhibits multi-band responses in the visible-to-near-infrared (vis-NIR) region.

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Galactose oxidase oxidation and glycosidase digestion for glycoRNA analysis.

Anal Methods

January 2025

Center for Clinical Mass Spectrometry, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.

Ribonucleic acid (RNA), essential for protein production and immune function, undergoes glycosylation, a process that attaches glycans to RNA, generating unique glycoRNAs. These glycan-coated RNA molecules regulate immune responses and may be related to immune disorders. However, studying them is challenging due to RNA's fragility.

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Carrier-Induced Room-Temperature Half-Metallicity in an Exfoliable Two-Dimensional Cr(TCNB) Metal-Organic Framework.

J Phys Chem Lett

January 2025

Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, CAS Key Laboratory of Materials for Energy Conversion, CAS Center for Excellence in Nanoscience, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China.

Half-metallicity, enabling 100% spin polarization, is pivotal for spintronics but remains challenging to achieve in low-dimensional materials. Using first-principles calculations, we theoretically propose an experimentally feasible two-dimensional (2D) metal-organic framework (MOF) magnetic semiconductor, Cr(TCNB) (TCNB = 1,2,4,5-tetracyanobenzene). This monolayer can be exfoliated from a Ag(100) substrate due to its low exfoliation energy of 0.

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ssDNA Capture Dynamics by Graphene Nanopores: The Role of Electrophoresis and Electro-osmotic Flow.

J Phys Chem Lett

January 2025

School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, People's Republic of China.

Efficient capture of single-stranded DNA (ssDNA) is crucial for high-throughput sequencing, which influences the speed and accuracy of genetic analysis. Electrophoresis (EP) and electro-osmotic flow (EOF) have a significant impact on the translocation behavior of ssDNA through the nanopore. Experimentally, dynamically tracking these two effects remains challenging, and conventional numerical methods also struggle to capture their dynamic properties in the presence of DNA.

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