Diarrheagenic Outbreak Reporting to Foodborne Disease Outbreaks Surveillance System - China, 2011-2022.

What Is Already Known About This Topic?: Foodborne diarrheagenic (DEC) outbreaks constitute a significant global public health concern, yet comprehensive data on outbreak incidence and epidemiological characteristics in China remain limited.

What Is Added By This Report?: Between 2011 and 2022, there were 413 foodborne DEC outbreaks reported to foodborne disease outbreak surveillance system, resulting in 8,127 illnesses, 2,565 hospitalizations, and one fatality. Enteroaggregative (EAEC) emerged as the predominant causative pathogen (48.

Epidemiological Characteristics of Sporadic Foodborne Diseases Caused by - China, 2013-2022.

Introduction: () is a common foodborne pathogen in coastal areas of China. Most epidemiological studies on have focused on foodborne disease outbreaks, with fewer studies based on long-term, continuous, and systematic sentinel surveillance.

Methods: Data were collected from the national foodborne disease active surveillance program in 31 provincial-level administrative divisions (PLADs) in China from 2013 to 2022.

Dietary Vitamin Intake Among Chinese Adults - 10 PLADs, China, 2022-2023.

What Is Already Known About This Topic?: Previous surveillance data from 2015-2017 showed that Chinese adults aged 18 to 59 years had mean daily vitamin intakes of 406.8 μg retinol equivalent (RE) for vitamin A, 36.7 mg for vitamin E, 0.

An Outbreak of Foodborne Botulism Caused by BoNT/A3 in Pickled Eggs - Weihai City, Shandong Province, China, July 2024.

What Is Already Known About This Topic?: Foodborne botulism is caused by botulinum neurotoxin (BoNT). () is a strictly anaerobic, Gram-positive bacterium, which is a key pathogen capable of producing BoNT. BoNTs can be classified into seven serotypes (A to G) based on their antigenic properties.

Synergistic integration of brain networks and time-frequency multi-view feature for sleep stage classification.

For diagnosing mental health conditions and assessing sleep quality, the classification of sleep stages is essential. Although deep learning-based methods are effective in this field, they often fail to capture sufficient features or adequately synthesize information from various sources. For the purpose of improving the accuracy of sleep stage classification, our methodology includes extracting a diverse array of features from polysomnography signals, along with their transformed graph and time-frequency representations.

Association between the immune-inflammation indicators and osteoarthritis - NHANES 1999-2018.

Background: Investigate the link between systemic immune-inflammatory index (SII) and Systemic Immune Response Index (SIRI) with osteoarthritis (OA) using National Health and Nutrition Examination Survey (NHANES) data (1999-2018).

Methods: Extracted NHANES data (1999-2018) and selected a study population based on demographic, examination, and laboratory data. Calculated SII (platelet count ​× ​neutrophil count/lymphocyte count) and SIRI (neutrophil count ​× ​monocyte count/lymphocyte count).

Best Evidence Summary of Home Enteral Tube Feeding Care Management in the Elderly.

Purpose: To evaluate and summarize the best evidence of home enteral tube feeding (HETF) care management in the elderly to provide an evidence-based basis for caregivers to implement care interventions.

Patients And Methods: Evidence on HETF care management in the elderly was retrieved from Chinese and international databases, guidelines, and websites of professional associations, including systematic reviews and expert consensuses, using the keywords of home enteral nutrition, home tube feeding, old, elder, home care, etc. The literature considered in this study was published from April 2019 to April 2024.

Lipid Nanoparticle (LNP) -A Vector Suitable for Evolving Therapies for Advanced Hepatocellular Carcinoma (HCC).

Hepatocellular carcinoma (HCC) stands as the predominant form of primary liver cancer, characterized by a dismal prognosis. Therapeutic options for advanced HCC remain sparse, with efficacy significantly hampered by the emergence of drug resistance. In parallel with research into novel pharmacological agents, advances in drug delivery systems represent a promising avenue for overcoming resistance.

Advances in Porous Structure Design for Enhanced Piezoelectric and Triboelectric Nanogenerators: A Comprehensive Review.

Porous structures offer several key advantages in energy harvesting, making them highly effective for enhancing the performance of piezoelectric and triboelectric nanogenerators (PENG and TENG). Their high surface area-to-volume ratio improves charge accumulation and electrostatic induction, which are critical for efficient energy conversion. Additionally, their lightweight and flexible nature allows for easy integration into wearable and flexible electronics.

Unveiling unexpected adverse events: post-marketing safety surveillance of gilteritinib and midostaurin from the FDA Adverse Event Reporting database.

Background: Gilteritinib and midostaurin are FLT3 inhibitors that have made significant progress in the treatment of acute myeloid leukemia. However, their real-world safety profile in a large sample population is incomplete.

Objectives: We aimed to provide a pharmacovigilance study of the adverse events (AEs) associated with gilteritinib and midostaurin through the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database.

Causal Relationships Between Blood Lipid Levels and Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis.

Background: In preliminary research and literature review, we identified a potential link between chronic obstructive pulmonary disease (COPD) and lipid metabolism. Therefore, this study employed Mendelian randomization (MR) analysis to investigate the potential causal connection between blood lipids and COPD.

Materials And Methods: A genome-wide association study (GWAS) on COPD was conducted, encompassing a total of 112,583 European participants from the MRC-IEU.

Peripheral Blood NMLR Can Predict 5-Year All-Cause Mortality in Patients with Chronic Obstructive Pulmonary Disease.

Background: Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary and systemic inflammation. The peripheral blood (neutrophil + monocyte)/lymphocyte ratio (NMLR) can predict the clinical outcomes of several inflammatory diseases. However, its prognostic value in COPD remains unknown.

Correlation of Sensitization with Mucus Plugging in COPD.

Background: Both sensitization and mucus plugs are associated with poor clinical outcomes in COPD. However, little is known about the association between hypersensitivity and mucus plugging in patients with COPD.

Methods: We retrospectively enrolled COPD patients who had visited Peking University Third Hospital and received measurement of the specific IgE ( sIgE) from Oct 1, 2018 to Sep 30, 2023.

Unveiling the Prognostic Power of HRR in ICU-Admitted COPD Patients: A MIMIC-IV Database Study.

Objective: This study sought to examine the potential relationship between Hemoglobin/Red Cell Distribution Width Ratio (HRR) and the all-cause mortality risk in critically ill patients with chronic obstructive pulmonary disease (COPD).

Patients And Methods: In a retrospective analysis of the MIMIC-IV database, patients were divided into two groups based on a specific HRR threshold. Propensity score matching (PSM) was employed to address covariate imbalances.

Wnt3a Enhances Mesenchymal Stem Cell Engraftment and Differentiation in a Chronic Obstructive Pulmonary Disease Rat Model.

Background: Bone marrow mesenchymal stem cell (BMSC) therapy is a novel approach for treating COPD. However, the difficulty in engraftment and easy clearance of BMSCs in vivo has hindered their clinical application. Hence, exploring effective methods to improve the engraftment and differentiation rates of BMSCs in vivo is urgent.

Unraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmonary Rehabilitation.

Background: Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation, airflow limitation, reduced health-related quality of life (HRQL), and exercise intolerance. Pulmonary rehabilitation (PR) is essential for COPD management, but outcomes may be influenced by individual physiological factors. Cardiopulmonary exercise testing (CPET) measures oxygen pulse (O2P), an indicator of stroke volume, yet the impact of baseline O2P on PR effectiveness remains unclear.

Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024.

Objective: There is increasing evidence that chronic obstructive pulmonary disease (COPD) is associated with coronary heart disease (CHD). In this study, we provide valuable insights in the field by examining the evolution of the relationship between COPD and CHD over the past 20 years.

Methods: A comprehensive computer search was conducted in the Web of Science (WOS) core dataset, covering literature on COPD combined with CHD from January 1, 2005, to August 20, 2024.

High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior.

Purpose: Airway disease is the main pathological basis of chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are unknown. Bone morphogenetic protein-7 (BMP7) is a multi-functional growth factor that belongs to the transforming growth factor superfamily, which affects the regulation of proliferation, differentiation, and apoptosis. Previous research has shown that BMP7 is highly expressed in the airway epithelia of patients with COPD, but its role in airway disease has not been fully elucidated.

The impact of public policy on enterprise innovation performance: Panel data on financial subsidy policy.

This study examined the impact of government subsidies on enterprise innovation performance in China. The fixed effects model was used for empirical analysis, utilizing panel data from 17,670 observations of 3703 listed A-share companies between 2012 and 2022, and the findings indicate that government subsidies significantly enhance enterprise innovation performance, with R&D investment serving as a partial mediator. The enterprise scale, ownership nature, and regional economic differences influenced the effectiveness of the subsidy.

Visual analysis of research hotspots and trends in traditional Chinese medicine for depression in the 21st century: A bibliometric study based on citespace and VOSviewer.

Background And Objectives: Depression long been a key concern for scholars worldwide; however, the field of depression has not received sufficient attention in traditional Chinese medicine. It was not until the 21st century that research into depression gradually entered a period of rapid development, with an increasing number of academic studies published in major journals. However, one limitation of this field is that no scholars have yet summarised the development process and key research issues.

Shifting dynamics of Sino-American competition in multi-aligned Middle East.

The Middle East (ME) is one of the most volatile regions of the world where things can change in the blink of an eye. China, once an ordinary energy customer showing hardly any interest in the politics of the ME, has turned itself into a crucial player in rapidly transforming geopolitical landscape of the ME. The increasing footprints of China in the ME pose challenges to the US interests in the region.

Encapsulated FeC boosted electrocatalytic performance for oxygen reduction reaction of N-doped carbon nanotube.

The shortcomings of precious metal based catalysts have limited the development of novel energies. So, developing low-cost and high performance transition metal based catalysts is one of the most feasible way to substitute the precious metal based catalysts. In all of the developed catalysts for oxygen reduction reactions (ORR), the iron-based nitrogen doped carbon nanotube (N-CNT) show great promise.

Exploring the link between exposure to volatile organic chemicals and incidence of infertility:A cross-sectional study.

Background: Growing evidence suggests that environmental pollutants exert a detrimental impact on female fertility. Among these pollutants, volatile organic compounds (VOCs), easily encountered in the environment, have garnered significant attention as prevalent airborne contaminants. Nevertheless, a definitive consensus regarding the association between VOCs and the incidence of infertility remains elusive.

Prob-sparse self-attention extraction of time-aligned dynamic functional connectivity for ASD diagnosis.

Dynamic functional connectivity (DFC) has shown promise in the diagnosis of Autism Spectrum Disorder (ASD). However, extracting highly discriminative information from the complex DFC matrix remains a challenging task. In this paper, we propose an ASD classification framework PSA-FCN which is based on time-aligned DFC and Prob-Sparse Self-Attention to address this problem.