A novel ANN-based feature subset selection in multi-scale granular ball neighborhood decision tables.

As an effective data preprocessing method, feature subset selection has been widely explored in recent years. However, the feature subset selection for the Wu-Leung model and its extended model involves high time complexity. Therefore, we combine the granular ball neighborhood rough set with the Wu-Leung model.

SAR remote sensing image segmentation based on feature enhancement.

Synthetic aperture radar (SAR) images are crucial in remote sensing due to their ability to capture high-quality images regardless of environmental conditions. Though it has been studied for years, the following aspects still limit its further improvement. (1) Due to the unique imaging mechanism of SAR images, the influence of speckle noise cannot be avoided.

Multimodal cross-scale context clusters for classification of mental disorders using functional and structural MRI.

The brain is a complex system with multiple scales and hierarchies, making it challenging to identify abnormalities in individuals with mental disorders. The dynamic segregation and integration of activities across brain regions enable flexible switching between local and global information processing modes. Modeling these scale dynamics within and between brain regions can uncover hidden correlates of brain structure and function in mental disorders.

Paying more attention on backgrounds: Background-centric attention for UAV detection.

Under the advancement of artificial intelligence, Unmanned Aerial Vehicles (UAVs) exhibit efficient flexibility in military reconnaissance, traffic monitoring, and crop analysis. However, the UAV detection faces unique challenges due to the UAV's small size in images, high flight speeds, and limited computational resources. This paper introduces a novel Background-centric Attention Module (BAM) to address these challenges.

EHM: Exploring dynamic alignment and hierarchical clustering in unsupervised domain adaptation via high-order moment-guided contrastive learning.

Unsupervised domain adaptation (UDA) aims to annotate unlabeled target domain samples using transferable knowledge learned from the labeled source domain. Optimal transport (OT) is a widely adopted probability metric in transfer learning for quantifying domain discrepancy. However, many existing OT-based UDA methods usually employ an entropic regularization term to solve the OT optimization problem, inevitably resulting in a biased estimation of domain discrepancy.

Case report: Vulvar metastasis after lung metastasis in cervical squamous cell carcinoma, a case report and literature review.

Introduction And Importance: Cervical cancer is highly correlated with high-risk human papillomavirus (HPV) infection, accounting for approximately 70 % of cases. However, false-negative HPV test results can occur, complicating early detection.

Case Presentation: We introduce a rare case of cervical cancer with lung metastasis followed by vulvar metastasis.

Cepharanthine: A promising natural compound against feline infectious peritonitis virus infection and associated inflammation.

Feline infectious peritonitis (FIP), a fatal disease in cats caused by feline infectious peritonitis virus (FIPV), has limited treatment options and lacks effective vaccines. Cepharanthine (CEP), a natural isoquinoline alkaloid, possesses many medicinal properties, including antiviral activities. However, the role of CEP in management of FIPV infection remains poorly understood.

Improving hemodialysis patient depression outcomes with acupuncture: A randomized controlled trial.

Objective: To evaluate the efficacy and safety of acupuncture as a supplementary treatment for mild to moderate depression in hemodialysis patients.

Method: This multicenter, randomized, controlled, single-masked trial included 64 hemodialysis patients aged 18-75 divided into two groups. One group received genuine acupuncture, while the other received sham acupuncture over 12 weeks.

Difficult airway management in 25 hospitals across China: A multicenter cross-sectional study.

Study Objective: Difficult airway management is a significant challenge in clinical anesthesia, critical care, and emergency medicine. Inadequate management can lead to severe complications including organ damage and death. This study assessed the variability in difficult airway management across China and focused on how patient and operator factors influenced outcomes in operating rooms.

Mitigating cadmium stress in rice (Oryza sativa L.) using succinic and oxalic acids with focus on cellular integrity and antioxidant responses.

Soil contamination with toxic heavy metals [such as cadmium (Cd)] is becoming a serious global problem due to the rapid development of the social economy. Organic chelating agents such as succinic acid (SA) and oxalic acid (OA) are more efficient, environmentally friendly, and biodegradable compared to inorganic chelating agents and they enhance the solubility, absorption, and stability of metals. To investigate this, we conducted a pot experiment to assess the impact of SA (0.

An R2R3-MYB transcription factor PdbMYB6 enhances drought tolerance by mediating reactive oxygen species scavenging, osmotic balance, and stomatal opening.

Drought is a major environmental challenge that hinders the growth and development of plants. R2R3-MYB transcription factors (TFs) play a vital role in mediating responses to abiotic stress; however, their specific functions in Populus davidiana × Populus bolleana hybrid poplar plants remain underexplored. This study focused on PdbMYB6, a novel R2R3-MYB TF identified in P.

CmTGA8-CmAPX1/CmGSTU25 regulatory model involved in trehalose induced cold tolerance in oriental melon seedlings.

Plants have developed complex regulatory networks to adapt to various stresses, including cold stress. Trehalose (Tre), known as the "sugar of life," plays a crucial role in enhancing cold tolerance by triggering antioxidation. However, the underlying regulatory mechanisms remain unclear.

Wheat glutenin allele 1Ax2∗ improves dough and bread quality without compromising yield.

High yield and good quality are two predominant objectives of most of the wheat breeding programs. Modulating HMW-GS composition is an effective approach to improve grain quality without yield penalty. In this study, we first analyzed the background similarity of three near-isogenic lines (NILs) with 1Ax-null, 1Ax1 or 1Ax2∗ alleles in the background of cultivar Xiaoyan-22 at the protein and DNA levels.

Bacillus pumilus G5 combined with silicon enhanced flavonoid biosynthesis in drought-stressed Glycyrrhiza uralensis Fisch. by regulating jasmonate, gibberellin and ethylene crosstalk.

Drought stress poses a significant threat to global agricultural production, including the cultivation of medicinal plants. Plant growth-promoting bacteria (PGPB) and the eco-friendly element silicon (Si) are known to alleviate the adverse effects of drought stress. This study examines how inoculation with Bacillus pumilus G5 or/and Si influences plant hormone signaling and flavonoid biosynthesis pathways in drought-stressed Glycyrrhiza uralensis Fisch.

U(VI) removal by zerovalent manganese modified corn straw biochar in acidic wastewater: Efficiency, characteristics and mechanism.

The chemical and radiological toxicity of uranium can present a significant risk to both human health and environmental safety. Thus, ZVMn-BC was synthesized through borohydride reduction aimed at investigating its performance in removing U(VI) in acidic environment (pH = 3). Several batch experiments were conducted to assess the sorption capability under various operational conditions and the relevant experimental data were investigated by kinetics, isotherms and thermodynamic equations.

Modelling assisted phytoextraction of heavy metals from tannery origin leachate.

The toxic tannery solid waste leachate (TSWL) containing heavy metals is generated after the percolation of rainwater in openly dumped tannery solid waste (TSW) which poses a serious threat to the surroundings by leaching down and bioaccumulation. For its management, the phytoextraction potential of Pistia stratiotes L. and Spirodela polyrhiza L.

Nanomedicine-enabled concurrent regulations of ROS generation and copper metabolism for sonodynamic-amplified tumor therapy.

Sonodynamic therapy (SDT) shows substantial potentials in cancer treatment thanks to the deep tissue penetration of ultrasound. However, its clinical translation suffers from the potential damages to healthy tissues and the resistance of tumors, particularly from cancer stem-like cells (CSCs), to the ultrasound. To address these challenges, we designed a novel glutathione (GSH)-activated nanomedicine to simultaneously enhance the safety and efficacy of SDT by in situ regulating the generation of reactive oxygen species (ROS) and copper metabolism.

Anti-neuroinflammatory agent rhein lysinate-based self-assembled injectable hydrogel loaded with ZL006 for promoting post-stroke functional recovery.

The therapeutic agent-based self-assembled hydrogel is gaining interest for biomedical applications, because it overcomes the poor biodegradability and low therapeutic agent loading of conventional polymer gelator-based hydrogel. Here, we present rhein lysinate (RHL), a therapeutic agent that self-assembles to form a stable hydrogel through the π-π stacking and hydrogen bonding interactions, while also exerting anti-neuroinflammatory effect. As a small molecular hydrogelator, RHL has significantly improved water solubility and enhanced self-assembly and gelation capabilities compared to the natural anthraquinone rhein.

Injectable oxidized high-amylose starch hydrogel scaffold for macrophage-mediated glioblastoma therapy.

Glioblastoma, characterized by rapid proliferation and invasiveness, is largely resistant to current treatment modalities. A major obstacle is the blood-brain barrier (BBB), which restricts the delivery of therapeutic agents as well as the infiltration of effective immune cells into glioblastoma. In this study, we developed an injectable oxidized high-amylose starch hydrogel (OHASM) to serve as a biomaterial scaffold for the delivery of macrophages and macrophage-polarizing drugs, aiming to bypass the BBB and enhance glioblastoma treatment.

Photochemical bomb: Precision nuclear targeting to activate cGAS-STING pathway for enhanced bladder cancer immunotherapy.

Activating the cGAS-STING pathway presents a promising strategy to enhance the innate immunity and combat the immunosuppressive tumor microenvironment. One key mechanism for triggering this pathway involves the release of damaged DNA fragments caused by nuclear DNA damage. However, conventional cGAS-STING agonists often suffer from limited nucleus-targeting efficiency and potential biotoxicity.

Bioinspired nanofiber dressings with counter-transport of exudate and drug for treating heavily exuding wounds.

Heavily exuding wounds are difficult to heal due to the accumulation of a large amount of exudates and the difficulty in efficient delivery of drugs by conventional wound dressings. Herein, inspired by the microstructure and function of octopus sucker (OS) and tree trunk (TT), we propose a bioinspired strategy to fabricate novel bioinspired OS&TT bilayered wound dressing, assembled by a lower OS-like nanofiber membrane with concave convex arrays and an upper TT-like nanofiber sponge with vertically aligned pores. The integration of bioinspired concave arrays and vertically aligned pores endows the bioinspired OS&TT dressing with dual vertical suction property, enabling effective drainage of significant amount of accumulated liquid.

Enhanced chemiluminescence of luminol via InS/MXene composite as a novel Co-reactant accelerator for UV-filter Benzophenone-3 determination.

In this study, a novel In₂S₃/MXene composite was developed as a co-reactant accelerator to enhance the chemiluminescence (CL) performance of the classical luminol-H₂O₂ system. The In₂S₃ and MXene heterojunction catalyzed the CL reaction through synergistic effect, facilitating the generation of reactive oxygen species and increasing CL intensities. This enhanced system was applied for the first time to detect an ultraviolet (UV) filter-benzophenone-3 (BP-3) by leveraging its light absorption property.

Reliable and specific biosensing on single- and double-stranded aptamer functionalized remote dual-gate organic field-effect transistors: A comparison.

Organic field-effect transistors (OFETs) integrated with commercial transistors are promising sensing platforms characterized by enhanced device uniformity, functional diversity, and electrical output stability. Aptamers with charged backbones and a high affinity for target molecules are anticipated to mitigate the limitations imposed by Debye screening in physiological environments with high ionic strength, thereby facilitating specific biological recognition in complex surroundings. This study presents two reliable OFET aptasensors for vascular endothelial growth factor (VEGF) and offers a systematic comparison of their performance.

Artificial intelligence enhanced microfluidic system for multiplexed point-of-care-testing of biological thiols.

Cysteamine (CA) serves as a cystine-depleting agent employed in the management of cystinosis and a range of other medical conditions. Monitoring blood CA levels at the point of care is imperative due to the risk of toxicity associated with elevated CA dosages. An additional significant challenge is presented by the intricate composition of human plasma and the presence of various interfering biological thiols, which possess similar structures or properties.