The attitudes of physicians toward nurse prescribing rights: a cross-sectional study.

Background: Nursing prescribing rights have been proposed in many countries, with physicians' attitudes playing an important role. This study aimed to investigate the attitudes of physicians toward nurse prescribing rights.

Methods: A cross-sectional study of 112 Chinese physicians was conducted from January to March 2024.

Whose autonomy support is more effective in promoting exercise adherence in higher vocational college students - based on self-determined theory.

Objective: Based on the self-determination theory, the three types of autonomy support of parents, teachers and peers as a whole were included in the same research system to explore their effects on exercise adherence of higher vocational college students and their internal mechanisms.

Methods: The study used the exercise autonomy support scale, autonomous motivation scale and exercise adherence scale to construct and test the hypothesised pathways for promoting exercise adherence among students in higher vocational college. Using the data obtained from a survey of 436 higher vocational college students as the unit of analysis, and taking into account the variable of students' self-determined motivation.

CCDC154 knockdown inhibits growth of liver cancer via suppressing expression of Snail.

Objective: The effect of coiled-coil domain-containing 154 (CCDC154) in liver cancer (LC) remains unexplored. The objective of this study was to investigate the role of CCDC154 in LC and its underlying mechanism.

Methods: The analysis of CCDC154 expression and prognosis was performed using UALCAN, Human Protein Atlas and Kaplan-Meier plotter websites.

Assessing validity and reliability of the Transition Shock Scale for Undergraduate Nursing Students (TSS, Chinese version) in associate degree nursing students.

Background: The Transition Shock Scale for Undergraduate Nursing Students assesses transition to undergraduate nursing students. The TSS is a tool used in various countries and has been translated into Chinese; however, associate degree nurses dominate China's nursing workforce, it needs to be validated in associate degree nursing interns. This study aimed to analyze the TSS (Chinese version) validity and reliability in Chinese associate degree nursing interns.

Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer.

Background: CD3 + CD20 + T cells (T cells) are a subset of lymphocytes in the human body that are associated with inflammation. They originate from T cells interacting with B cells, and their levels are abnormally elevated in individuals with immune disorders, as well as in some cancer patients. The interplay between tumor immunity and inflammation is intricate, yet the specific involvement of T cells in local tumor immunity remains uncertain, with limited research on their subtypes.

Leadless pacemaker implantation in a patient with congenital azygos continuation of the inferior vena cava.

In case of venous route abnormality during a leadless pacemaker (LP) implantation, it can be challenging if we still performed via the predesigned femoral vein. We report a patient with normal preoperative laboratory and image results, but azygos continuation of the inferior vena cava (IVC) was suspected during the procedure. Then, we decided to change the implantation strategy, the LP implantation was successfully performed via right jugular vein instead of the classical IVC route.

The complete chloroplast genome sequences of monotypic genus Pseudogalium, and comparative analyses with its relative genera.

Background: Pseudogalium is a new monotypic genus with two subspecies in China and one in Japan, which holds a distinctive phylogenetic position and ecological significance within the tribe Rubieae. Chloroplast genomes contain abundant information for resolving phylogenetic relationships. To investigate the phylogenetics of P.

Indoor ventilation frequency and cognitive function among Chinese old adults: the multiple mediation effect of anxiety and self-rated health.

Background: China is experiencing an increasingly serious aging population. Cognitive function is an important factor and guarantee for the quality of life of older people. Therefore, to achieve healthy aging, this study aimed to examine the sequential multiple mediating effects of indoor ventilation frequency and cognitive function on anxiety and self-rated health in the Chinese older people population.

Amarogentin suppresses cell proliferation and EMT process through inducing ferroptosis in colorectal cancer.

Background: Colorectal cancer (CRC) is one common tumor with the high death rate, and badly affects the normal lives of CRC patients. Amarogentin (AG) has been found to exhibit regulatory roles and join into the progression of multiple diseases. However, the regulatory impacts and associated molecular mechanisms of AG in CRC progression keep unclear.

Induction by caterpillars of stored and emitted volatiles in terpene chemotypes from populations of wild cotton (Gossypium hirsutum).

Background: Upland cotton (Gossypium hirsutum) plants constitutively store volatile terpenes in their leaves, which are steadily emitted at low levels. Herbivory leads to a greater release of these stored volatiles. Additionally, damaged plants increase the accumulation of volatile terpenes in their leaves and begin to synthesize and emit other terpenes and additional compounds.

Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway.

Background: Ursodeoxycholic acid (UDCA), traditionally recognized for its hepatoprotective effects, has also shown potential in protecting kidney injury. This study aimed to evaluate the protective effects of UDCA against sepsis-induced acute kidney injury (AKI) and to elucidate the underlying mechanisms.

Methods: Sixty male C57BL/6 N mice were utilized to establish a sepsis-induced AKI model through intravenous injection of lipopolysaccharides (LPS, 10 mg/kg).

Effects of combined application of nitrogen, phosphorus, and potassium fertilizers on seed yield, seed quality and economic returns of Elymus nutans in alpine region.

The Qinghai-Tibetan Plateau (QTP), one of the most important ecological regions in the world, is experiencing a decline in ecological function as a result of severe grassland degradation. Elymus nutans is one of the ecological grass species for restoring degraded grasslands in QTP. The seed yield and seed quality are often limited by soil nutrients in QTP, so it is very important to optimize the application rates of fertilizer for E.

Change point detection in brucellosis time series from 2010 to 2023 in Xinjiang China using the BEAST algorithm.

Brucellosis is a significant global challenge, but there has been a lack of epidemiological studies on brucellosis in Xinjiang from a change point perspective. This study aims to bridge this gap by employing sequence decomposition and identifying significant change points, with datasets sourced from the Xinjiang Disease Prevention and Control Information System. This study employed the BEAST algorithm to decompose the brucellosis time series in Xinjiang from 2010 to 2023, while simultaneously identifying change points in the decomposed seasonal and trend components.

The impact of air pollution on career changes among Chinese workers.

The influence exerted by air pollution on interregional workforce migration has garnered considerable attention in ecological economics over time; however, relatively scant consideration has been given to its effects on occupational transition dynamics. This study presents an empirical examination of the influence of air pollution on job changes among the working population and seeks to understand the underlying causal mechanisms. By merging detailed micro-level survey data with regional Fine particulate matter (PM) data from Chinese counties spanning the years 1997 to 2015, we have constructed an extensive database to support our analysis.

Design and mechanical analysis of a novel modular bionic earthworm robot with upright functionality.

With the escalating demand for exploration within confined spaces, bionic design methodologies have attracted considerable attention from researchers, primarily due to the intrinsic limitations of human access to hazardous environments. However, contemporary bionic robots primarily attain linear motion through the axial radial deformation of their body segments, thereby lacking the upright functionality that is characteristic of these organisms. In response to the limitations associated with current bionic earthworm robots concerning upright capability and stiffness modulation, we propose an innovative bionic robot that incorporates upright functionality and programmable stiffness.

Equilibrium study of logistics demand and logistics resource allocation in Guangdong Province.

Logistics serve as a vital link between production and consumption. The balanced allocation of logistics demand and resources can promote the harmonious development of the logistics system, thereby fostering regional economic growth. As a leading region in China's reform and opening-up, Guangdong Province has experienced high economic growth.

Stable quantum droplets with high-order vorticity in zero-order Bessel lattice.

A theoretical framework is presented to investigate the stability of novel two-dimensional quantum droplets within zeroth-order Bessel lattices. The evolution of quantum droplets is studied by the Gross-Pitaevskii equations with Lee-Huang-Yang corrections. The circular groove structure inherent in the zeroth-order Bessel lattice potential facilitates the formation of distinct configurations, including stable zero-vorticity annular quantum droplets and annular quantum droplets featuring embedded vorticity.

Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia.

FMS-like tyrosine kinase-3 (FLT3), a class 3 receptor tyrosine kinase, can be activated by mutations of internal tandem duplication (FLT3-ITD) or point mutations in the tyrosine kinase domain (FLT3-TKD), leading to constitutive activation of downstream signaling cascades, including the JAK/STAT5, PI3K/AKT/mTOR and RAS/MAPK pathways, which promote the progression of leukemic cells. Despite the initial promise of FLT3 inhibitors, the discouraging outcomes in the treatment of FLT3-ITD-positive acute myeloid leukemia (AML) promote the pursuit of more potent and enduring therapeutic approaches. The histone acetyltransferase complex comprising the E1A binding protein P300 and its paralog CREB-binding protein (p300/CBP) is a promising therapeutic target, but the development of effective p300/CBP inhibitors faces challenges due to inherent resistance and low efficacy, often exacerbated by the absence of reliable clinical biomarkers for patient stratification.

Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade.

Previously, we demonstrated that natural host-defence peptide caerin 1.1/caerin 1.9 (F1/F3) increases the efficacy of anti-PD-1 and therapeutic vaccine, in a HPV16 + TC-1 tumour model, but the anti-tumor mechanism of F1/F3 is still unclear.